The prevalence and epidemiological characteristics of hepatitis B virus and hepatitis C virus coinfection in Turkey

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dc.contributor.authorAygen B.
dc.contributor.authorÇelen M.K.
dc.contributor.authorKöksal I.
dc.contributor.authorTosun S.
dc.contributor.authorKarabay O.
dc.contributor.authorYamazhan T.
dc.contributor.authorYildiz O.
dc.date.accessioned2024-04-24T17:58:24Z
dc.date.available2024-04-24T17:58:24Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractWe aimed to determine prevalence and epidemiological characteristics of cases coinfected with hepatitis B virus (HBV)/hepatitis C virus (HCV) in Turkey. Material and Methods: The data for this study was obtained from Turk-Hepatitis Registry (HEP-NET) Project, which includes real-life cohort of hepatitis patients from 15 centers in Turkey, and is supported by Viral Hepatitis Society. In the project, 10,165 hepatitis cases were evaluated in 10 hospitals. Results: According to initial visit results, HBV/HCV coinfection was detected in 99 patients. The ratio was 974/100 000. The mean age of the cases was 40.9+21.7 years, 56.6% of them were males and 43.4% were females,. The major risk factors were dental therapy, any surgical procedure, hemodialysis and blood transfusion. The mean alanine aminotransferase (ALT) levels were 70.9±49.1 IU/L in coinfected patients. In 12% of cases HBeAg was positive. The median HCV RNA level was found 0 IU/mL (minimum: 50-maximum: 2.18x107 IU/mL), and the median HBV DNA level was found 2.50x102 IU/mL (minimum: 12-maximum: 1.70x108 IU/mL). In 8.1% of the patients both HCV RNA and HBV DNA were positive, and in 87.5% of cases HCV infection was dominant. The most important risk factor was hemodialysis (25%) in this group. Conclusion: This is the most detailed study which evaluates the prevalence of HBV/HCV coinfection in Turkey. HBV/HCV coinfection prevalence was not higher than HBV or HCV monoinfections. In cases where both HCV RNA and HBV DNA were positive, HCV was predominant. © 2013 by Türkiye Klinikleri.en_US
dc.identifier.doi10.5336/medsci.2012-32319
dc.identifier.endpage1249en_US
dc.identifier.issn1300-0292
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-84888147017en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1245en_US
dc.identifier.urihttps://doi.org/10.5336/medsci.2012-32319
dc.identifier.urihttps://hdl.handle.net/11468/23901
dc.identifier.volume33en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherTurkiye Kliniklerien_US
dc.relation.ispartofTurkiye Klinikleri Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoinfectionen_US
dc.subjectEpidemiologyen_US
dc.subjectHepatitis Ben_US
dc.subjectHepatitis Cen_US
dc.titleThe prevalence and epidemiological characteristics of hepatitis B virus and hepatitis C virus coinfection in Turkeyen_US
dc.title.alternativeTürkiye'de hepatit B virüs ve hepatit C virus koenfeksiyonu prevalansi{dotless} ve epidemiyolojik özelliklerien_US
dc.typeArticleen_US

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