Role of D-Dimer, Fibrinogen and D-Dimer/Fibrinogen Rate in the Diagnosis of Pulmonary Embolism

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dc.contributor.authorYilmaz, Sureyya
dc.contributor.authorTopcu, Fusun
dc.contributor.authorAtes, Gungor
dc.contributor.authorYildiz, Tekin
dc.contributor.authorBogatekin, Gulhan
dc.date.accessioned2024-04-24T17:49:47Z
dc.date.available2024-04-24T17:49:47Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: The migration of a blood clot from the systemic circulation to pulmonary veins is called pulmonary embolism (PE). Pulmonary embolism is difficult to diagnose. The aim of the present study is to investigate the utility and diagnostic contribution of d-dimer, fibrinogen level, and Ddimer/ Fibrinogen (D/F) rate which are quick, non-invasive, affordable and easily obtainable laboratory tests in PE. Methods: We have evaluated the diagnostic value of D/F rate in 118 patients who were suspected to have PE. Diagnosis of PE was made by computerized tomographic pulmonary angiography. D-dimer level was above normal in all patients. Initially, Wells clinical scoring was applied on the patients and their d-dimer and fibrinogen levels were measured. Results: Seventy seven patients were detected as PE positive (+) and 41 were detected as PE negative (-). Forty-eight of the cases (40.7%) were male; the average age was 49.77 +/- 19.46 (15-86) years. Between PE (+) and PE (-) patients, d-dimer, fibrinogen, and D/F rate median values and standard derivations were detected to be different and statistically significant. Conclusion: According to this study approach to the patients with suspected from PE, D/F ratio is valuable than d-dimer, and fibrinogen level is significantly lower in patients with PE (+) than patients with PE (-).en_US
dc.identifier.endpage91en_US
dc.identifier.issn1309-3878
dc.identifier.issue2en_US
dc.identifier.startpage86en_US
dc.identifier.urihttps://hdl.handle.net/11468/22938
dc.identifier.volume8en_US
dc.identifier.wosWOS:000375099700003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherDuzce Univen_US
dc.relation.ispartofKonuralp Tip Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPulmonary Embolismen_US
dc.subjectD-Dimeren_US
dc.subjectFibrinogenen_US
dc.titleRole of D-Dimer, Fibrinogen and D-Dimer/Fibrinogen Rate in the Diagnosis of Pulmonary Embolismen_US
dc.titleRole of D-Dimer, Fibrinogen and D-Dimer/Fibrinogen Rate in the Diagnosis of Pulmonary Embolism
dc.typeArticleen_US

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