Are thyroid functions affected in children diagnosed with COVID-19?

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dc.authorid0000-0001-5137-0501en_US
dc.authorid0000-0002-9809-0977en_US
dc.contributor.authorYılmaz, Kamil
dc.contributor.authorÜnal, Edip
dc.date.accessioned2023-08-01T06:16:21Z
dc.date.available2023-08-01T06:16:21Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractIntroduction: In December 2019, a novel type of coronavirus infection (SARS-CoV-2) emerged in China and started to spread rapidly. It is unclear whether the thyroid gland is affected in patients with COVID-19. We aimed to investigate the changes in thyroid function in pediatric patients with COVID-19. Material and Method: This study enrolled 79 patients aged 0-18 years with confirmed COVID-19 and the control group consisted of 57 healthy children. All patients thyroid function tests and acute phase reactants were studied. Results: The median age was 132 months in the patient group and 108 months in the control group. TSH level was lower in the COVID-19 patients compared to the controls although the difference did not statistical significance (p=0.051). Free T3 level was significantly lower in the patient group compared to the control group (p<0.001). All patients with COVID-19 had normal TSH levels and fT3 was lower in 7 (8.8%) of 79 patients. Correlation analysis showed a negative correlation between fT3 level and CRP, procalcitonin levels. No significant correlation was found between disease severity and thyroid hormone levels. Conclusion: as far as we know, our study is the first to evaluate thyroid functions in children with COVID-19. As in many other severe disease states, ESS may develop in COVID-19. It can be concluded that the pituitary-thyroid axis is not severely affected in pediatric patients COVID-19, especially in those with asymptomatic or mildly symptomatic disease. It should be remembered that the disease course may be more severe particularly in patients who develop ESS.en_US
dc.identifier.citationYılmaz, K. ve Ünal, E. (2021). Are thyroid functions affected in children diagnosed with COVID-19?. Journal of Health Sciences and Medicine, 4(3), 257-261.en_US
dc.identifier.doi10.32322/jhsm.891646
dc.identifier.endpage261en_US
dc.identifier.issn2636-8579
dc.identifier.issue3en_US
dc.identifier.startpage257en_US
dc.identifier.trdizinid1154102
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1154102
dc.identifier.urihttps://hdl.handle.net/11468/12368
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1154102
dc.identifier.volume4en_US
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorYılmaz, Kamil
dc.institutionauthorÜnal, Edip
dc.language.isoenen_US
dc.publisherMediHealth Academy Yayıncılıken_US
dc.relation.ispartofJournal of Health Sciences and Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjectEuthyroid sick syndromeen_US
dc.subjectfT3en_US
dc.subjectThyroiden_US
dc.titleAre thyroid functions affected in children diagnosed with COVID-19?en_US
dc.titleAre thyroid functions affected in children diagnosed with COVID-19?
dc.typeArticleen_US

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