ANTI-TUBERCULOSIS DRUG RESISTANCE IN SOUTHEAST OF TURKEY

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dc.contributor.authorDal, Tuba
dc.contributor.authorOzcan, Nida
dc.contributor.authorTekin, Recep
dc.contributor.authorTekin, Alicem
dc.contributor.authorCelen, Mustafa Kemal
dc.contributor.authorOzekinci, Tuncer
dc.contributor.authorDal, T.
dc.date.accessioned2024-04-24T17:44:36Z
dc.date.available2024-04-24T17:44:36Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Tuberculosis is a globally prevalent life-threatening infectious disease. In this study we aimed to evaluate antibiotic suscebtibility rates of Mycobacterium tuberculosis complex strains. Materials and methods: A total of 150 culture-positive samples were included in. Among culture positive samples 86 were Mycobacterium tuberculosis complex and 64 were non-tuberculous mycobacterium. Of Mycobacterium tuberculosis complex isolated samples 45 were Ziehl-Neelsen positive. Of 64 non-tuberculous mycobacterium isolated samples 15 were Ziehl-Neelsen positive. Mean age of the patients with tuberculosis was 37.74 +/- 20.53 and non-tuberculous mycobacterium isolated patients was 46.80 +/- 23.32. Antibiotic susceptibility testing was performed for the four first-line anti-tuberculosis drugs by BACTEC MGIT-960 instrument (Becton Dickinson). Of M. tuberculosis strains 41 % was resistant to at least one or more of the drugs (isoniasid 27.9%, ethambutol 8.13%, streptomycin 12.79 %, rifampicine 9.3 %). Of the strains 5.8 % was resistant to two, 3.4 % to three and 3.4 % to four drugs. Conclusion: Mycobacterium tuberculosis complex and drug resistance of this microorganism continued to be a problem for our country and non-tuberculous mycobacterium species may become a problem in the future. We thought that a strong and cost-effective tuberculosis control programme contributes to reduce the incidence of drug resistance in the community.en_US
dc.identifier.endpage46en_US
dc.identifier.issn0393-6384
dc.identifier.issue1en_US
dc.identifier.startpage41en_US
dc.identifier.urihttps://hdl.handle.net/11468/22180
dc.identifier.volume29en_US
dc.identifier.wosWOS:000337927000006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMycobacterium Tuberculosisen_US
dc.subjectSusceptibilityen_US
dc.subjectFirst-Line Antibioticsen_US
dc.titleANTI-TUBERCULOSIS DRUG RESISTANCE IN SOUTHEAST OF TURKEYen_US
dc.titleANTI-TUBERCULOSIS DRUG RESISTANCE IN SOUTHEAST OF TURKEY
dc.typeArticleen_US

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