Pseudomonas aeruginosa; Virulence Factors and Host Defense Mechanisms
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Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Veysi AKPOLAT
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
As an opportunistic pathogen, Pseudomonas aeruginosa (P. aeruginosa) can cause both acute and chronic infections. Variable virulence components and antibiotic resistance markers in the bacterium's genome constitute the bacterium's pathogenic profile and provide the bacterium with outstanding metabolic adaptability to many conditions. The interactions of P. aeruginosa with the host are poorly understood, complicating the treatment of its infections and the development of vaccines against them. Despite decades of scientific research focusing specifically on this challenge, vaccines to prevent these dangerous infections still do not exist. The major virulence factors of P. aeruginosa and host immune responses against the bacteria are discussed in this review.
Açıklama
Anahtar Kelimeler
Pseudomonas aeruginosa, virulence factors, host immune response, Pseudomonas aeruginosa, virulence factors, host immune response
Kaynak
International Archives of Medical Research
WoS Q Değeri
Scopus Q Değeri
Cilt
15
Sayı
1
