Hypothalamus-anterior pituitary axis dysfunction in stroke: TSH responses to administration of IV TRH

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dc.authorid0000-0002-5299-9480en_US
dc.contributor.authorTaşdemir, Nebahat
dc.contributor.authorHaspolat, Yusuf Kenan
dc.contributor.authorTaşdemir, Mehmet
dc.date.accessioned2021-12-01T13:27:28Z
dc.date.available2021-12-01T13:27:28Z
dc.date.issued2006en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalıen_US
dc.description.abstractWe aimed to determine whether the lesion affected hypothalamus-anterior pituitary axis in 38 patients with cerebrovascular hemorrhage and infarct who did not have a thyroid disorder. For this purpose, we measured levels of serum thyroid hormones; T3 (triiodothyronin), T4 (tyroxin), FT3 (free T3), FT4 (free T4) and TSH (thyroid stimulating hormone) at 0 minute and TSH hormones were measured bu RIA (radioimmunoassay) at 20 and 60 minutes after administering IV 500 µg TRH at 8:00 am. Results were compared with the control group comprising 17 euthyroidic subjects. In stroke patients, responses of TSH to TRH were variable and 28.9% had low response (n=11), 5.3% extremely delayed response (n=2) and 65.8% normal responses (n=25). TSH parameters of 25 patients with stroke and 13 patients with axis dysfunction (case group) were compared with normal control group parameters. TSH values were found to be significantly lower in stroke patients compared to the control group (p<0.001, p<0.001 respectively).en_US
dc.identifier.citationTaşdemir, N., Haspolat, Y. K. ve Taşdemir, M. (2006). Hypothalamus-anterior pituitary axis dysfunction in stroke: TSH responses to administration of IV TRH. Biotechnology & Biotechnological Equipment, 20(2), 115-119.en_US
dc.identifier.doi10.1080/13102818.2006.10817352
dc.identifier.endpage119en_US
dc.identifier.issn1310-2818
dc.identifier.issn1314-3530
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-33745773993
dc.identifier.scopusqualityQ3
dc.identifier.startpage115en_US
dc.identifier.urihttps://www.tandfonline.com/doi/abs/10.1080/13102818.2006.10817352
dc.identifier.urihttps://hdl.handle.net/11468/8349
dc.identifier.volume20en_US
dc.indekslendigikaynakScopus
dc.institutionauthorTaşdemir, Nebahat
dc.institutionauthorHaspolat, Yusuf Kenan
dc.institutionauthorTaşdemir, Mehmet
dc.language.isoenen_US
dc.publisherTaylor & Francis Groupen_US
dc.relation.ispartofBiotechnology & Biotechnological Equipment
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHypothalamusen_US
dc.subjectHypothalamus-anterior pituitaryen_US
dc.subjectTSHen_US
dc.subjectIV TRHen_US
dc.titleHypothalamus-anterior pituitary axis dysfunction in stroke: TSH responses to administration of IV TRHen_US
dc.titleHypothalamus-anterior pituitary axis dysfunction in stroke: TSH responses to administration of IV TRH
dc.typeArticleen_US

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