Epidermal growth factor receptor (egfr) immunolocalization in the sialoadenectomized rat ovaries

Basit Öğe Kaydı
dc.contributor.authorKetani, Muzaffer
dc.contributor.authorKaloǧlu, Celal
dc.contributor.authorKetani, Şennur
dc.contributor.authorUysal, Ersin
dc.date.accessioned2024-04-24T17:56:18Z
dc.date.available2024-04-24T17:56:18Z
dc.date.issued2004
dc.departmentDicle Üniversitesi, Veteriner Fakültesi, Temel Bilimler Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalıen_US
dc.description.abstractIntra-ovarian regulation of follicular maturation is modulate by various factors. Among these, Epidermal growth factor (EGF) is vital factor. Epidermal growth factor (EGF) have potent mitogenic effects on granulosa and theca cells. The aim of present study was to investigate the effects of sialoadenectomy on the distrubution of immunoreactive epidermal growth factor receptor (EGFR) in the rat ovaries. Twenty Adult female Wistar albino rats were divided into two groups, a control and one experimental groups. The experimental groups of rats were subjected to sialoadenectomy in order to create EGF deficiency. After 60 days of sialoadenectomy (EGF deficiency) and control group rats were killed by pentobarbital and their ovaries removed. The sections were stained with APAAP immunohistochemical staining for evaluation using a light microscope. A statistically significant reduced body weight was noted in the experimental groups of rats when compared to the control group. This marked EGFR immunoreactivity was maintained in control rat ovaries, whereas it deacreased in sialoadenectomized rat ovaries. In conclusion, the present study indicated that there is paralel relationship between ovary follicule cells EGFR immunolocalization and EGF deficiency.en_US
dc.identifier.citationKetani, M., Kaloǧlu, C., Ketani, Ş. ve Uysal, E. (2004). Epidermal growth factor receptor (egfr) immunolocalization in the sialoadenectomized rat ovaries. Biotechnology and Biotechnological Equipment, 18(2), 135-140.
dc.identifier.doi10.1080/13102818.2004.10817101
dc.identifier.endpage140en_US
dc.identifier.issn1310-2818
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-3242699007
dc.identifier.scopusqualityQ3
dc.identifier.startpage135en_US
dc.identifier.urihttps://doi.org/10.1080/13102818.2004.10817101
dc.identifier.urihttps://hdl.handle.net/11468/23433
dc.identifier.urihttps://www.tandfonline.com/doi/abs/10.1080/13102818.2004.10817101
dc.identifier.volume18en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofBiotechnology and Biotechnological Equipment
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEpidermal growth factor receptor (egfr) immunolocalization in the sialoadenectomized rat ovariesen_US
dc.titleEpidermal growth factor receptor (egfr) immunolocalization in the sialoadenectomized rat ovaries
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Epidermal Growth Factor Receptor EGFR Immunolocalization in the Sialoadenectomized Rat Ovaries.pdf
Boyut:
2.14 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu