Genetic Polymorphisms of Cyp19 and Myostatin Genes in Turkish Indigenous Sheep Breeds

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dc.contributor.authorAkis, I
dc.contributor.authorGursel, Esen F.
dc.contributor.authorCakmak, Hacihasanoglu N.
dc.contributor.authorAtmaca, G.
dc.contributor.authorYardibi, H.
dc.contributor.authorAtes, A.
dc.contributor.authorDurak, M. H.
dc.date.accessioned2024-04-24T17:48:14Z
dc.date.available2024-04-24T17:48:14Z
dc.date.issued2017
dc.departmentDicle Üniversitesien_US
dc.description.abstractGrowth and meat production traits are very important in sheep breeding. Cyp19 gene has a major role in reproductive activity and growth due to its function in estrogen synthesis. Another gene affecting growth traits is Myostatin (MSTN) gene, which mainly regulates skeletal muscle growth. In this study allele frequencies of genetic polymorphism in Cyp19 and Myostatin genes were identified by PCR-RFLP method in five indigenous Turkish sheep breeds, Chiose, Imroz, Kivircik, Zom and Morkaraman. Digestion of Cyp19 gene with HaeIII only revealed uncut AA genotype and digestion of MSTN with DraI also revealed only uncut AA genotype. Both loci analyzed in this study were found to be monomorphic in five Turkish indigenous sheep breeds. These highly conserved parts of the two genes can be useful for molecular evolutionary studies in sheep. Further studies regarding association analysis of Cyp19 and MSTN in sheep should be conducted.en_US
dc.description.sponsorshipIstanbul University, Faculty of Veterinary Medicine [VET-TB-16-1, VET-TB-16-2, BEK-2016-22550, BEK-2017-24900]en_US
dc.description.sponsorshipThis study was supported by Istanbul University, Faculty of Veterinary Medicine with project numbers VET-TB-16-1, VET-TB-16-2, BEK-2016-22550 and BEK-2017-24900en_US
dc.identifier.endpage318en_US
dc.identifier.issn1792-2720
dc.identifier.issue3en_US
dc.identifier.startpage313en_US
dc.identifier.urihttps://hdl.handle.net/11468/22935
dc.identifier.volume68en_US
dc.identifier.wosWOS:000418954600008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherHellenic Veterinary Medical Socen_US
dc.relation.ispartofJournal of The Hellenic Veterinary Medical Society
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCyp19en_US
dc.subjectMyostatinen_US
dc.subjectSheepen_US
dc.subjectSnpen_US
dc.subjectPcr-Rflpen_US
dc.titleGenetic Polymorphisms of Cyp19 and Myostatin Genes in Turkish Indigenous Sheep Breedsen_US
dc.titleGenetic Polymorphisms of Cyp19 and Myostatin Genes in Turkish Indigenous Sheep Breeds
dc.typeArticleen_US

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