Primary thyroid lymphoma: mucosa associated lymphoid tissue lymphoma case

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dc.contributor.authorAlabalik, Ulas
dc.contributor.authorKeles, Ayse Nur
dc.contributor.authorTurkcu, Gul
dc.contributor.authorKucukoner, Mehmet
dc.contributor.authorAvci, Yahya
dc.contributor.authorBuyukbayram, Huseyin
dc.date.accessioned2024-04-24T17:27:39Z
dc.date.available2024-04-24T17:27:39Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractPrimary thyroid lymphomas are lymphomas which are localized only to thyroid gland or thyroid gland and surrounding lymph nodes. Frequently these are mucosa associated lymphoid tissue (MALT) lymphomas with B cell origin. Our case is a 78-year-old female patient who admitted with a neck mass and had been operated with the suspicion of malignancy. Histopathological examination revealed diffuse proliferation of atypical lymphoid cells that consists of small to medium sized cells, with irregular nuclear contours, some of which resemble centrocytes. Immunohistochemical staining was positive for CD20, CD79alpha, CD43, and lambda while negative for CD3, CD30, CD15, bcl-2, bcl-6, CD68, CD138, CD5, and CD10. With these finding, the case was considered as primary thyroid MALT lymphoma. Thyroid MALT lymphomas are characterized with the presence of atypical lymphocytes that originate from the marginal zones of lymhoid follicles. Immunohistochemically, while these lymphomas express the B cell associated antibodies (CD20, CD22, CD79a), conversely CD5, CD10, and CD3 expressions are not seen.en_US
dc.identifier.doi10.5455/GMJ-30-39089
dc.identifier.endpage100en_US
dc.identifier.issn2564-7784
dc.identifier.issn2564-7040
dc.identifier.issue1en_US
dc.identifier.startpage98en_US
dc.identifier.urihttps://doi.org/10.5455/GMJ-30-39089
dc.identifier.urihttps://hdl.handle.net/11468/20119
dc.identifier.volume20en_US
dc.identifier.wosWOS:000439222100020
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherAves Press Ltden_US
dc.relation.ispartofEuropean Journal of Therapeutics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCd20en_US
dc.subjectMalt Lymphomaen_US
dc.subjectThroiden_US
dc.titlePrimary thyroid lymphoma: mucosa associated lymphoid tissue lymphoma caseen_US
dc.titlePrimary thyroid lymphoma: mucosa associated lymphoid tissue lymphoma case
dc.typeArticleen_US

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