The relationship between coagulation factor XI levels and cardiac syndrome X in patients with diabetes mellitus

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dc.contributor.authorYazicioglu M.V.
dc.contributor.authorYuksel M.
dc.contributor.authorBatgerel U.
dc.contributor.authorAcar G.
dc.contributor.authorAvci A.
dc.contributor.authorSimsek Z.
dc.contributor.authorTabakci M.M.
dc.date.accessioned2024-04-24T18:46:12Z
dc.date.available2024-04-24T18:46:12Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractCardiac syndrome X (CSX) is a characterized with normal epicardial coronary arteries and exertional angina pectoris. The aim of this study was to measure the levels of coagulation factor XI (F XI) and XII (F XII) to compare the intrinsic coagulation pathway activities in DM patients with and without CSX. A total of 50 Type 2 DM patients with CSX diagnosed by non-invasive tests accompanied with coronary angiography, and control group of 51 Type 2 DM patients matching with the CSX group in terms of age and sex were included in the study. F XII levels were tended to be higher in patient group than controls [107 ± 26 vs 99 ± 21 IU/dL; p = 0.124, respectively]. Moreover F XI levels were found to be significantly higher in CSX patient group compared to the controls [130 ± 23 IU/dL vs 118 ± 17 IU/dL; p = 0.005, respectively]. This study demonstrates that intrinsic coagulation pathway of DM patients with CSX is more active than those without CSX. It is also suggested that hypercoagulability may play an important role in the pathogenesis of CSX.en_US
dc.identifier.endpage3165en_US
dc.identifier.issn1205-6626
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-84902299959
dc.identifier.scopusqualityN/A
dc.identifier.startpage3159en_US
dc.identifier.urihttps://hdl.handle.net/11468/25104
dc.identifier.volume20en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherCardiology Academic Pressen_US
dc.relation.ispartofExperimental and Clinical Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAngina Pectorisen_US
dc.subjectCardiac Syndrome Xen_US
dc.subjectCoagulation Factorsen_US
dc.subjectCoronary Angiographyen_US
dc.subjectDiabetesen_US
dc.subjectHypercoagulabilityen_US
dc.titleThe relationship between coagulation factor XI levels and cardiac syndrome X in patients with diabetes mellitusen_US
dc.titleThe relationship between coagulation factor XI levels and cardiac syndrome X in patients with diabetes mellitus
dc.typeArticleen_US

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