Determination of Antibacterial Efficacy of Lactoferrin Glycoprotein Obtained from Cow Colostrum

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dc.contributor.authorSabancılar, İlhan
dc.contributor.authorToprak, Gülten
dc.contributor.authorTemiz, Hakan
dc.date.accessioned2025-03-08T18:27:45Z
dc.date.available2025-03-08T18:27:45Z
dc.date.issued2023
dc.departmentDicle Üniversitesi
dc.descriptionTIP 20.029.
dc.description.abstractObjective: It was aimed to investigate the antibacterial effect levels of Lactoferrin protein in cow colostrum. The aim of the study was to evaluate the effect of lactoferrin protein obtained from a natural product on the growth of Escherichia coli, Pseudomonas aerugenosa and Staphylococcus aureus. Method: Lactoferrin at 4 different concentrations (100 mg/ml, 50 mg/ml, 25mg/ml and 12.5mg/ml) was impregnated on 6 mm discs prepared from filter paper and placed on the MHA plate and after incubation at 37°C for 24 hours, inhibition was evaluated. The antibacterial effect levels of naturally obtained lactoferrin at different concentrations were compared. Results: It was determined that the antibacterial activity of lactoferrin against Gram-negative bacteria Pseudomonas aeruginosa was higher than the other bacterial species in the study. It was determined that Lactoferrin at a concentration of 12.5mg/ml had the least inhibitory effect in the studied bacteria. It was concluded that E.coli and S. aureus were bacteria resistant to the antibacterial activity of lactoferrin. Conclusion: It was observed that this effect was limited in E.coli bacteria. In the light of these results, it was concluded that Lactoferrin, an antibacterial agent, has different antibacterial effects depending on the bacterial species and dose.
dc.description.sponsorship[TR] This study was supported by Dicle University Scientific Research Project Coordinator
dc.identifier.doi10.56484/iamr.1326284
dc.identifier.endpage34
dc.identifier.issn2146-6033
dc.identifier.issn2146-6033
dc.identifier.issue2
dc.identifier.startpage27
dc.identifier.urihttps://doi.org/10.56484/iamr.1326284
dc.identifier.urihttps://hdl.handle.net/11468/31188
dc.identifier.volume15
dc.language.isoen
dc.publisherVeysi AKPOLAT
dc.relation.ispartofInternational Archives of Medical Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_21250205
dc.subjectCow colostrum
dc.subjectlactoferrin
dc.subjectantibacterial effect and whey protein.
dc.titleDetermination of Antibacterial Efficacy of Lactoferrin Glycoprotein Obtained from Cow Colostrum
dc.typeArticle

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