THE RELATIONSHIP BETWEEN TRACE ELEMENTS AND CERULOPLASMIN WITH SEVERITY OF FASCIOLIASIS PATIENTS

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dc.contributor.authorBasarali, Mustafa Kemal
dc.contributor.authorKaplan, Ibrahim
dc.contributor.authorCicek, Mutalip
dc.contributor.authorCakir, Fatih
dc.date.accessioned2024-04-24T17:44:25Z
dc.date.available2024-04-24T17:44:25Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of our study is to evaluate the relationship between trace elements, as zinc (Zn) and copper (Cu), and acute phase reactant ceruloplasmin (CP) levels during fascioliasis hepatic infection. 45 patients with fascioliasis and 38 healthy controls were enrolled in the study. Fascioliasis was diagnosed with ELISA IgG, stool examination and radiologic imaging. Number of females and males were determined as 34111 and 3018 in patient and control groups respectively. Mean age was 38.1 +/- 11.7 and 358 +/- 16.9 years in patient and control groups, respectively. Blood samples were collected to determine plasma Zn, Cu, and CP levels. As a result of the study serum Cu (from 1.4 to 1.8) and CP (from 26.7 to 33.4) levels were rised in while Zn (from 1.1 to 1.9) level was decreased in patient group. We determinated significant correlation (r: 0.781) of fasciola titers with ceruloplasmine that increased by acute phase in the patients with fascioliasis. In conclusion, an high correlation between CP and Cu levels in patients suffering from fascioliasis can be noted. On the other hand, low Zn levels, especially in endemic areas of disease, suggested that Zn can be given in addition to medical treatment, or as a dietary supplement. This situation may lead the way in terms of increasing the efficiency of treatment of fascioliasis.en_US
dc.identifier.endpage181en_US
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue2en_US
dc.identifier.startpage177en_US
dc.identifier.urihttps://hdl.handle.net/11468/22042
dc.identifier.volume29en_US
dc.identifier.wosWOS:000337927100006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFascioliasisen_US
dc.subjectZincen_US
dc.subjectCopperen_US
dc.subjectCeruloplasminen_US
dc.titleTHE RELATIONSHIP BETWEEN TRACE ELEMENTS AND CERULOPLASMIN WITH SEVERITY OF FASCIOLIASIS PATIENTSen_US
dc.titleTHE RELATIONSHIP BETWEEN TRACE ELEMENTS AND CERULOPLASMIN WITH SEVERITY OF FASCIOLIASIS PATIENTS
dc.typeArticleen_US

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