Effects of concentration and volume of ropivacaine in epidural anesthesia

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dc.contributor.authorTekeli T.
dc.contributor.authorÖlmez G.
dc.contributor.authorÖzyilmaz M.A.
dc.date.accessioned2024-04-24T17:58:36Z
dc.date.available2024-04-24T17:58:36Z
dc.date.issued2004
dc.departmentDicle Üniversitesien_US
dc.description.abstractEffect of local anesthetic concentration and volume on the epidural anesthetic properties is unclear. This study was performed to determine effects of a therefold difference in concentration and volume ropivacaine on epidural anesthesia. Sixty adult patients, ASA I-II, scheduled for lower limb surgery were included in this prospective, double blind study. Patients were randomly divided into three group with 20 in each. Group I received 1% ropivacaine in 10 mL volume (100 mg), Group II 0.5% ropivacaine in 10 mL volume (100 mg); and Group III 0.75% ropivacaine in 20 mL volume (150 mg) via epidural route. The groups compared with local anaesthetic properties, hemodinamic effects and adverse effects. Sensory anesthesia was adequate for surgery in all of the patients. The onset of sensorial analgesia at the T10 dermatome in groups III was faster than Group II (p<0.05). Times to regression of anesthesia to T10 and T12 dermatoma increased in Group III. These changes were not statistically significant. The degree of motor blockade at 20 min and 120 min by using the Bromage scale was higher than the other group (p<0.001). Cardiovascular changes were similar in all three groups. Finally; intensity of sensory and motor block from epidural anesthesia with ropivacaine appears to depend primarily on total milligram dose and ropivacaine 0.75% in a volume of 20 mL proved to be a very potent local anesthetic with moderate motor blockade.en_US
dc.identifier.endpage270en_US
dc.identifier.issn1300-0578
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-11944263730en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage265en_US
dc.identifier.urihttps://hdl.handle.net/11468/24009
dc.identifier.volume12en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.relation.ispartofAnestezi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEpidural Anaesthesiaen_US
dc.subjectRopivacaineen_US
dc.titleEffects of concentration and volume of ropivacaine in epidural anesthesiaen_US
dc.title.alternativeEpidural anestezi uygulamasinda ropivakainin doz ve volümünün etkilerien_US
dc.typeArticleen_US

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