BRUCELLOSIS IS A MAJOR PROBLEM: A FIVE YEARS EXPERIENCE
dc.contributor.author | Dal, Tuba | |
dc.contributor.author | Celen, Mustafa Kemal | |
dc.contributor.author | Ayaz, Celal | |
dc.contributor.author | Dal, Mehmet Sinan | |
dc.contributor.author | Kalkanli, Sevgi | |
dc.contributor.author | Mert, Duygu | |
dc.contributor.author | Yildirim, Necmettin | |
dc.date.accessioned | 2024-04-24T17:47:35Z | |
dc.date.available | 2024-04-24T17:47:35Z | |
dc.date.issued | 2013 | |
dc.department | Dicle Üniversitesi | en_US |
dc.description.abstract | Brucellosis is a chronic granulomatous infection which is endemic in Mediterranean countries and Turkey. The aim of this study is to analyze the clinical, laboratory findings and therapeutic features in patients with brucellosis. A retrospective study was conducted with 91 patients who developed brucellosis between 2005 to 2009. The diagnosis was based on clinical findings compatible with brucellosis, serological tests positive, and/or isolation of Brucella species from blood, or other tissues. The mean age was 33 years (16-67 years). Sixty-threes of patients (69.2%) were male. Forty (44%) cases had an occupational history relevant for Brucella exposure and 85 (93%) cases consumption with contaminated animal product. The mean diagnostic delay was 15 days, much longer in focal brucellosis. A total of 77 (85 %) cases had acute brucellosis. The focal brucellosis complications were observed in 39 (42.8%) cases: osteoarticular involvement 32 (82%), epididymo-orchitis 4 (10%), and central nervous system involvement 3 (8%). Chronic brucellosis occurs in 3 (3.3%) cases. Clinical manifestations included non-specific symptoms such as fever (95%). sweats (90%), arthralgia and lower back pain (63%). Of the patients 84 (92%) had serological titre =1/160 and 28 (31%) blood cultures were positive. All of the patients were cured by antibiotic therapy (Doxycycline+rifampicin/streptomycine, streptomycine+rifampicin/Doxycycline, ceftiraxone/rifampicin). Relapse was observed in 5 (5.4%) patients. Brucellosis is an infection with multiple presentations. Its early diagnosis was mandatory to avoid severe complications. | en_US |
dc.identifier.endpage | 670 | en_US |
dc.identifier.issn | 0393-6384 | |
dc.identifier.issn | 2283-9720 | |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 665 | en_US |
dc.identifier.uri | https://hdl.handle.net/11468/22619 | |
dc.identifier.volume | 29 | en_US |
dc.identifier.wos | WOS:000330151200010 | |
dc.identifier.wosquality | Q4 | |
dc.indekslendigikaynak | Web of Science | |
dc.language.iso | en | en_US |
dc.publisher | Carbone Editore | en_US |
dc.relation.ispartof | Acta Medica Mediterranea | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Brucellosis | en_US |
dc.subject | Relapses | en_US |
dc.subject | Mediterranean | en_US |
dc.title | BRUCELLOSIS IS A MAJOR PROBLEM: A FIVE YEARS EXPERIENCE | en_US |
dc.title | BRUCELLOSIS IS A MAJOR PROBLEM: A FIVE YEARS EXPERIENCE | |
dc.type | Article | en_US |