Bir sığırcılık işletmesinde çoklu antibiyotik dirençli pseudomonas aeruginosa epidemisi
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Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Dicle Üniversitesi Veteriner Fakültesi
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
İthal holştayn ırkı sığırlardan oluşan 1000 başlık özel bir süt işletmesinde buzağılarda görülen enteritis, irinli deri yaraları, poliartritis, apse gibi klinik bozukluklar ve % 24 (60/250) oranındaki ölümler nedeniyle Harran Üniversitesi Veteriner Fakültesi Mikrobiyoloji Anabilim Dalı’na başvuruldu. Alınan klinik materyallerin bakteriyolojik muayenesi sonucunda etken P. aeruginosa olarak identifiye edildi. Elde edilen izolatın antibiyotik duyarlılığını saptamak için Kirby Bauer Disk Diffüzyon yöntemi ile ampisilin, amoksisilin, amokisilin/klavulanik asit, sefoksitin, siprofloksasin, eritromisin, gentamisin, imipenem, norfloksasin, oksasillin, penisilin, rifampin, streptomisin, tetrasiklin, trimetoprim-sulfametoksazol ve vankomisin test edildi. İmipenem duyarlı olarak saptanırken, diğer antibiyotiklerde zon oluşumu görülmedi ve dirençli olarak değerlendirildi. Sonuç olarak çoklu antibiyotik direncine sahip P. aeruginosa suşlarının neden olduğu infeksiyonların işletmelerde ciddi kayıplar oluşturabileceği, tedavide başarı sağlamak için laboratuvar muayeneleri ve antibiyotik duyarlılık testinin önemli olduğu kanısına varıldı.
It was applied to Harran University Veterinary Faculty Microbiology Department because of the fact that clinical disorders such as enteritis, purulent skin wounds, polyarthritis, and abscess and a 2424 %(60/250) mortality ratio seen among lambs in a private milk enterprise which was consisted of a 1000 imported Holstein cattle’s. Agent was identified as P. aeruginosa as a result of bacteriological examination of collected clinic materials. Ampicillin, amoxicillin, amoxicillin/clavulanic acid, cefoxitin, ciprofloxacin, erythromycin, gentamycin, imipenem, norfloxacin, oxacillin, penicillin, rifampin, streptomycine, tetracycline, trimethoprim-sulfamethoxazol ve vancomycin were tested by Kirby Bauer Disk Diffusion test for determining antibiotic sensitivity of the obtained isolate. While it was obtained sensitive to imipenem, any zone forming wasn’t seen to the rest of the antibiotics and it was accepted as resistant. As a result it was concluded that infections caused by P. aeruginosa which has multiple antibiotics resistivity can lead serious losses in bread stocks and laboratory examinations, and antibiotic sensitivity test are important for achieving treatment success.
It was applied to Harran University Veterinary Faculty Microbiology Department because of the fact that clinical disorders such as enteritis, purulent skin wounds, polyarthritis, and abscess and a 2424 %(60/250) mortality ratio seen among lambs in a private milk enterprise which was consisted of a 1000 imported Holstein cattle’s. Agent was identified as P. aeruginosa as a result of bacteriological examination of collected clinic materials. Ampicillin, amoxicillin, amoxicillin/clavulanic acid, cefoxitin, ciprofloxacin, erythromycin, gentamycin, imipenem, norfloxacin, oxacillin, penicillin, rifampin, streptomycine, tetracycline, trimethoprim-sulfamethoxazol ve vancomycin were tested by Kirby Bauer Disk Diffusion test for determining antibiotic sensitivity of the obtained isolate. While it was obtained sensitive to imipenem, any zone forming wasn’t seen to the rest of the antibiotics and it was accepted as resistant. As a result it was concluded that infections caused by P. aeruginosa which has multiple antibiotics resistivity can lead serious losses in bread stocks and laboratory examinations, and antibiotic sensitivity test are important for achieving treatment success.
Açıklama
Anahtar Kelimeler
Pseudomonas aeruginosa, Çoklu direnç, Sığır, Multiresistance, Cattle
Kaynak
Dicle Üniversitesi Veteriner Fakültesi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
1
Sayı
1
Künye
Keskin, O., Tel, O.Y. ve Arserim, N.B. (2012). Bir sığırcılık işletmesinde çoklu antibiyotik dirençli pseudomonas aeruginosa epidemisi. Dicle Üniversitesi Veteriner Fakültesi Dergisi, 1(1), 30-33.
