Expression of VEGF in Fallopian tubes in Ovarian Ischemia-Reperfusion

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dc.contributor.authorToprak, Veysel
dc.contributor.authorDeveci, Engin
dc.date.accessioned2025-02-22T14:13:31Z
dc.date.available2025-02-22T14:13:31Z
dc.date.issued2023
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: Our aim was to investigate expression level of VEGF in tuba uterine in ovarian ischemia-reperfusion (I/R) by immunohistochemical techniques. Material and Methods: 30 Sprague Dawley female rats were categorized into three groups. Sham group: The abdomen was opened and closed without any treatment. Ischemia (I) group: 1-hour ischemia was allowed to create ischemic injury. Ischemia-reperfusion (I/R) group: 1-hour ischemia and then 3-hour reperfusion was allowed to create I/R injury. Results: MDA and MPO levels were increased after ischemia and IR while GSH content was decreased. Histological scores of follicular degeneration, inflammation, hemorrhage were high in I and IR groups. Normal histology of tuba uterine was observed in sham group. In I and IR group, degenerated cilia, desquamative epithelial cells impaired basement membrane leukocytes infiltration, apoptotic nuclei, vascular dilatation, thrombosis and inflammation and adenoma were observed. VEGF expression was mainly in sham group. In I and IR group, endothelial cells, adenoma structures, vessels, macrophage and inflammatory leukocyte cells and fibroblast cells showed positive VEGF expression. Conclusion: IR damage affected inflammation and angiogenesis, changes in implantation.en_US
dc.identifier.doi10.37990/medr.1240419
dc.identifier.endpage341en_US
dc.identifier.issn2687-4555
dc.identifier.issue2en_US
dc.identifier.startpage337en_US
dc.identifier.trdizinid1263470en_US
dc.identifier.urihttps://doi.org/10.37990/medr.1240419
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1263470
dc.identifier.urihttps://hdl.handle.net/11468/30039
dc.identifier.volume5en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofMedical records-international medical journal (Online)en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_TR_20250222
dc.subjectHistopathologyen_US
dc.subjectfallopian tubesen_US
dc.subjectVEGFen_US
dc.subjectischemia-reperfusionen_US
dc.titleExpression of VEGF in Fallopian tubes in Ovarian Ischemia-Reperfusionen_US
dc.typeArticleen_US

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