RELATIONSHIP BETWEEN SERUM LIPIDS AND COLON POLYPS: A PILOT STUDY
[ X ]
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Carbone Editore
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background/Aim: The relationship between dyslipidemia and various malignancies is still unclear. We therefore investigated the possible relationship between atherogenic dyslipidaemia and colon polyps and assessed the predictive role of dyslipidaemia in the development of colorectal cancer. Methods: The study involved patients evaluated at the Gastroenterology Clinic of HaydarpasaNumune Training and Research Hospital between October 2, 2011, and November 16, 2012. Data were collected from 74 patients with colon polyps (advanced and low-grade dysplasia [LGD]) and 57 healthy control subjects. Results: Triglyceride (p=0.001) and high-density lipoprotein (HDL)-cholesterol (p<0.01) concentrations were significantly higher in patients with advanced dysplasia (AD) than in the control group. Triglyceride (p=0.001) and HDL-cholesterol (p<0.01) concentrations were also significantly higher in patients with LGD than in the control group. Triglyceride and HDL-cholesterol concentrations, however, were similar in the AD and LGD groups. Conclusions: Atherogenic dyslipidaenzia is significantly associated with adenoma, suggesting that it could be involved in adenoma development. Atherogenic dyslipidaemia should not be ignored in colorectal cancer prevention programs.
Açıklama
Anahtar Kelimeler
Polyps, Dyslipidaemia, Triglyceride
Kaynak
Acta Medica Mediterranea
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
30
Sayı
1
