RELATIONSHIP BETWEEN SERUM LIPIDS AND COLON POLYPS: A PILOT STUDY
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Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
Carbone Editore
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Background/Aim: The relationship between dyslipidemia and various malignancies is still unclear. We therefore investigated the possible relationship between atherogenic dyslipidaemia and colon polyps and assessed the predictive role of dyslipidaemia in the development of colorectal cancer. Methods: The study involved patients evaluated at the Gastroenterology Clinic of HaydarpasaNumune Training and Research Hospital between October 2, 2011, and November 16, 2012. Data were collected from 74 patients with colon polyps (advanced and low-grade dysplasia [LGD]) and 57 healthy control subjects. Results: Triglyceride (p=0.001) and high-density lipoprotein (HDL)-cholesterol (p<0.01) concentrations were significantly higher in patients with advanced dysplasia (AD) than in the control group. Triglyceride (p=0.001) and HDL-cholesterol (p<0.01) concentrations were also significantly higher in patients with LGD than in the control group. Triglyceride and HDL-cholesterol concentrations, however, were similar in the AD and LGD groups. Conclusions: Atherogenic dyslipidaenzia is significantly associated with adenoma, suggesting that it could be involved in adenoma development. Atherogenic dyslipidaemia should not be ignored in colorectal cancer prevention programs.
Description
Keywords
Polyps, Dyslipidaemia, Triglyceride
Journal or Series
Acta Medica Mediterranea
WoS Q Value
Q4
Scopus Q Value
Volume
30
Issue
1
