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Öğe Amelogenin knockout mice mimic physical tooth characteristics of human amelogenesis imperfecta.(Int Amer Assoc Dental Researchi A D R/A A D R, 2003) Kulkarni, G. V.; Hatakeyama, J.; Yavuz, I.; Rosca, G.; Khadivi, A.; Gibson, C. W.; Kulkarni, A. B.[Abstract Not Available]Öğe A case of Beckwith-Wiedemann syndrome with peculiar dental findings(Ariesdue Srl, 2016) Callea, M.; Yavuz, I.; Clarich, G.; Gunay, A.; Vinciguerra, A.; Unal, M.; Sahbaz, C.Background Beckwith-Wiedemann syndrome (BINS, OMIM 130650) is a rare genetic disorder characterised by overgrowth, tumor predisposition and congenital malformations. Few systemic manifestations and oral features have been reported so far. Case report We report on a case of BWS, describing all features expanding the knowledge on oro-dentofacial phenotypes, along with a review of the literature.Öğe Craniofacial and upper airway cephalometrics in hypohidrotic ectodermal dysplasia(British Inst Radiology, 2007) Arslan, S. Guenduez; Kama, J. Devecioglu; Ozer, T.; Yavuz, I.Objectives: The aim of this study was to evaluate the craniofacial and upper airway structures in patients with hypohidrotic ectodermal dysplasia (HED). Subjects and methods: Craniofacial and upper airway dimensions were measured on lateral cephalometric radiographs of ten HED patients (four females and six males) and ten normal class III patients as a control group. 21 dimensional measurements were used for cephalometric assessment. Craniofacial structures were compared with normal values and airway dimensions were compared with those of a control group with a similar skeletal pattern. Results: We found that the SNA degrees, SNB degrees, ANB degrees, SN-GoMe degrees and the distance between the lips and the S-line were lower than those in normal subjects, while soft tissue convexity angles were higher in HED patients. Statistically significant decreases occurred in tongue length, vertical airway length, hyoid bone mandibular plane length, hyoid bone C3 length, middle airway space and inferior airway space, while the soft palate length increased. Conclusions: The characteristic craniofacial features of HED patients are class III malocclusion with maxillary retrusion and deficiency in vertical, transversal and sagittal growth of the jaw and soft tissues. HED patients have smaller pharyngeal and upper airway dimensions, and the hyoid bone is positioned more posteriorly compared with class III control individuals.Öğe THE DETAILED EVALUATION OF SUPERNUMERARY TEETH WITH THE AID OF CONE BEAM COMPUTED TOMOGRAPHY(Taylor & Francis Ltd, 2010) Tumen, E. C.; Yavuz, I.; Tumen, D. S.; Hamamci, N.; Berber, G.; Atakul, F.; Uysal, E.The aim of this paper is to demonstrate the application of a recently developed three-dimensional imaging system, cone beam computed tomography, in the detailed evaluation of supernumerary teeth. Two-hundred and twenty three patients with supernumerary teeth (68 females and 155 males) were included in this study. Patients ranged in age from 12 to 25 years. Supernumerary teeth were detected by clinical examination and traditional radiographies. Moreover careful investigation for more details was made with the cone beam computed tomography. Supernumerary teeth which were detected with the examinations of the cone beam computed tomography images were classified according to the number location, shape and eruption rate. The prevalence of supernumerary teeth was determined to be 1.45% of the study population. Males were affected more than females in a ratio of 2.3:1. Supernumerary teeth were most frequently located in 86.2% of the cases in the maxilla; 10.1% in the mandible and 3.7% both in the maxilla and mandible. Supernumerary teeth were most commonly conical in shape (68.8%). One supernumerary tooth was present in 67.7% of the patients, 30.9% had two, and 1.4% had three supernumeraries. Definite and early diagnosis of the supernumerary teeth is very important. Detailed examinations and evaluations of these teeth with three-dimensional images is very benefical in terms of treatment planning and preventing complications which may occurÖğe Effect of extremely low frequency magnetic field on enamel microhardness in rats(Ariesdue Srl, 2011) Kargul, B.; Yavuz, I.; Akdag, M. Z.; Durhan, A.Aim The potential effects on human health of extremely low frequency magnetic field (ELF-MF) are of considerable concern. In the present study it was investigated the effect of long term ELF-MF exposure on microhardness of rat teeth. Materials and methods Thirty male Sprague-Dawley rats were divided into three groups. The first and second experimental groups (n=10) were exposed to 100 mu T and 500 mu T ELF-MF during 10 months, 2 hours a day respectively For the control group, nothing was applied to the rats and they completed their life cycle in the cage during the study period. After ELF-MF exposure, microhardness of enamel surface was determined for each group. Results The decrease in microhardness in the second experimental group was found to be statistically significant compared to the control group (P<0.05). However, no statistical difference was found between the first and second experimental groups (P>0.05). Conclusion From the results it can be concluded that 500 mu T level of magnetic field strengths may have a certain negative effect on enamel mineralisation. Further investigations are necessary to analyse the effect of ELF-MF on teeth.Öğe EFFECT OF MOBILE PHONES ON TRACE ELEMENTS CONTENT IN RAT TEETH(Taylor & Francis Ltd, 2008) Adiguzel, O.; Dasdag, S.; Akdag, M. Z.; Erdogan, S.; Kaya, S.; Yavuz, I.; Kaya, F. A.Widespread use of wireless communication made it necessary to investigate the long term effect of mobile phone, which is the most popular technological equipment in the earth. One of the important parts of body that absorbs, radiation emitted from mobile phones is oral tissue. However mobile phone users and also scientists usually do not pay attention on effect of mobile phone e exposure on oral tissue. Therefore, there is no epidemiological and experimental studies focused on this part of body. The aim of this study was to investigate the of GSM (Global System for Mobile Communication) -Modulated 900 MHz radiofrequency radiation 017 trace element content of rat teeth. Thirty one Wistar Albino adult male rats were divided into three groups: experimental group (each, n=14), shame group (n=7), and cage control group (n=10). Head of the rats in the experimental group were & exposed to GSH-Modulated 900 MHz radiofrequency radiation for 2 hours per day during ten months. At the end of the exposure period, the contents of some trace elements as Ca, Mg, Zn, and P were measured in the oral tissue. The measurements were performed by Atomic Absorption Spectrophotometry (AAS). However phosphorus content of teeth was measured h.); ultraviolet spectrophotometer (UVS). Changes of Mg, and Zn contents in the experimental group were found to be statistically significant according to the sham and cage control groups. Ca and P contents in the (experimental group were higher than the sham and cage control groups. Difference between the groups was not statistically significant (p>0.05). The results of the study showed that GSM-Modulated 900 MHz radiofrequency radiation can be a factor to alter the teeth trace elements' densities. However further studies are necessary to know whether GSM-Modulated 900 MHz radiofrequency, radiations affects the oral tissues such as the teeth.Öğe The effectiveness of a three-stage routing scheme for patients with lichen planus of the oral mucosa(Clinical Dentistry LLC, 2022) Shkarin, V. V.; Makedonova, Yu A.; Dyachenko, Svetlana V.; Gavrikova, Lyudmila M.; Belonozhkina, Darya A.; Yavuz, I.The problem of effective routing of patients with lichen planus of the oral mucosa remains relevant. The goal is to supplement and systematize the routing scheme of patients with this pathology and evaluate its effectiveness. Materials and methods. The study involved 32 patients who applied to dental medical organizations (StMO) of level I, 36 patients observed in StMO of level II, 46 patients from StMO of level III who were randomized into 3 groups: Group I - patients who applied to StMO of level I and to whom generally accepted methods of patient management were applied; Group II - monitoring of patients was carried out in StMO level II with the use of conventional treatment, group III - patients from StMO level III, to whom their own original management methodology was applied. Results. On the 3rd day of therapy, the severity of pain syndrome (1.43 points) was significantly lower in group III both in relation to the indicators before treatment (2.84 points) and relative to the indicators of the control group (1.85 points, p<0.05). There was also a difference in the severity of the intensity of edema and hyperemia, which in patients of group III became 1.2 times less from the start of treatment and 1.05 times less than in patients of the control group. This trend continued at all periods of observation. When monitoring the course of lichen planus in patients observed at the place of residence, positive dynamics was revealed, however, 38 patients due to the ineffectiveness of treatment, according to the routing scheme, were sent to dental medical organizations of the III level, where clinical stabilization of the process was achieved using digital monitoring and treatment methods. Conclusion. A comparative clinical study determined the effectiveness of the routing scheme to improve the quality of dental care for patients with lichen planus of the oral mucosa.Öğe The effects of antibacterial solutions on microorganisms isolated from infected root canals in vivo(2006) Ercan, Ertuǧrul; Dülgergil, Türksel Çoruh; Yavuz, I.; 0000-0002-4753-6553; 0000-0001-6953-747XObjective: This study assessed the in vivo antimicrobial activity of NaOCl, Chx, Ca(OH)2, and H2O2 against five different microorganisms: Enterococcus faecalis, Porphyromonas endodontalis, Streptococcus salivarius, Lactobacillus sp., and S. aureus. Study design: Eighty infected teeth in seventy patients with pulpal or periapical pathology were studied. After preparing a standard access cavity. Sterilized paper points were used to take samples from the root canals. These were incubated in test tubes at 37°C for 72 hours. Of the resulting bacteria, the five most frequent strains were examined. The teeth were divided into four equal groups. After preparing the root canal using the step-back technique until a number 55 file, each group was subjected to one of the following irrigation solutions: 2% chlorhexidine gluconate (Chx), 5% NaOCl, Ca(OH)2 in distilled-water, or 3% H2O2. After irrigation, a temporary filling was placed in each cavity. The same irrigation procedure was repeated three and six days later. Then, the microbiologic sampling was also repeated. The chi-squared test was used for statistical comparisons. Results: Of the irrigants tested in this in vivo study, chlorhexidine was the most effective against all the microorganisms isolated from infected root canals, followed by NaOCl, Ca(OH)2, and H2O2. However, differences among the three groups were not statistically significant, except against Enterococcus faecalis (p>0.05). Conclusions: Our results did highly confirm the fact from previous studies that chx with 2% percent is the most effective antibacterial agent after three consecutive irrigations. Furthermore, in vitro and in vivo studies are necessary to assess whether the Chx imparted substantive dissolve organic material.Öğe The effects of extremly low frequency magnetic field and mangan to the oral tissues(Diagnosis Press Ltd, 2008) Kaya, S.; Celik, M. S.; Akdag, M. Z.; Adiguzel, O.; Yavuz, I.; Turnen, E. C.; Ulku, S. Z.Exposure to extremely low frequency magnetic field (ELFMF) originating from daily electrical-electronic appliances and electric lines, is a common thing. Recently, the discussions focused on the topic whether ELFMF had any harmful effects over health or not. Several previous studies displayed that ELFMF significantly increased bone mineral density. The aim of the present study was to investigate the influence of ELFMF and manganese over mineral accumulation in head and jaw bones of rats. Previous studies showed that manganese plays a significant role over normal development of enamel and dentin alongside contributing to the calcium and phosphorous association. In the present study, the effects of exposure to ELFMF and manganese on mineral density and histology of teeth, were investigated. In the present study, 64 male Wistar albino rats were divided into 8 groups. Amount of mineral elevations were determined in head and jaw bones of the first 6 groups (p <.05) and histologic alterations were found in teeth of rats. The obtained results indicated that ELFMF plays an important role over mineral density and histologic structure of cranial and jaw bones in rats. In conclusion, further epidemiological and experimental laboratory studies are required for more detailed evaluation of the effects of ELFMF on cranial and jaw bones of rats.Öğe Efficacy test of a toothpaste in reducing extrinsic dental stain(Iop Publishing Ltd, 2017) Agustanti, A.; Ramadhani, S. A.; Adiatman, M.; Rahardjo, A.; Callea, M.; Yavuz, I.; Maharani, D. A.This clinical trial compared the external dental stain reduction achieved by tested toothpaste versus placebo in adult patients. In this double-blind, parallel, randomised clinical trial, 45 female volunteers with a mean age of 20 years old were included. All study subjects front teeth were topically applicated with Silver Diamine Fluoride (SDF) to create external dental stains. Subjects were randomized into test (n=22) and control (n=23) groups. Toothpastes were used for two days to analyse the effects of removing external stains on the labial surfaces of all anterior teeth. VITA Easyshade Advance 4.0 was used to measure dental extrinsic stains changes. The analysis showed statistically significant efficacy of the tested toothpaste in reducing external dental stain caused by SDF, comparing to the placebo toothpaste, after one and two days of usage. The tested toothpaste was effective in reducing dental stain.Öğe Incisor trauma in a Turkish preschool population: Prevalence and socio-economic risk factors(F D I World Dental Press Ltd, 2011) Tumen, E. C.; Adiguzel, O.; Kaya, S.; Uysal, E.; Yavuz, I.; Ozdemir, E.; Atakul, F.Objective: This study aimed to assess the prevalence of traumatic injuries of the primary incisors in preschool children from 2 to 5 years old in South-Eastern Anatolia, Turkey. Additionally, the relationship between traumatic dental injuries, parents' education level, family income, size of incisal overjet and the presence of anterior open bite were examined. Basic research design: A cross-sectional survey Clinical settings: Data were collected through oral examinations and structured interviews, and included socio-economic indicators. Participants: A total of 727 children of both genders were included in the study. 122 of these children were aged 2; 183 aged 3; 178 aged 4 and 186 aged 5. Results: The prevalence of dental injuries was 8.0% (n=58). The highest frequency of trauma in the primary teeth was observed at the age of 4. Boys experienced more dental injuries than girls, 12.2% and 4.0%, respectively. The most common crown fracture was in enamel only (57%) followed by crown fracture of enamel and dentin (19%). Conclusion: The prevalence of dental injuries in Turkish preschool children was very low. The children with incisal overjet greater than 5mm and anterior open bite experienced more dental injuries in primary teeth than their counterparts with normal occlusion. Socio-economic indicators were not statistically significantly associated with the occurrence of traumatic dental injuries.Öğe Investigation of microorganisms in infected dental root canals(2006) Ercan, Ertuǧrul; Dallı, Mehmet; Yavuz, I.; Özekinci, Tuncer; 0000-0002-4753-6553; 0000-0001-6953-747XObjective: The purpose of this study is to investigate the type of microorganisms isolated from necrotic pulp tissues and from failed endodontic treatments in infected root canals. Methods: This study is based on an experiment conducted on 90 patients between November, 2002 and November, 2003 using a sampling. One hundred single root canals were microbiologically sampled from these patients by using sterile paper points. Among 100 canals sampled, 61 had primary infection and 39 had a history of secondary infection. Microorganisms were isolated and identified by using established advanced microbiologic techniques for anaerobic species. Results: A total of 197 cultivable isolates were recovered, the microbial findings in both types of canals, such as the number of species isolated, the 68.0% of Gram-positives and 27.9% gram-negatives, the 52.8% of facultative and 43.1 % strict anaerobic microorganisms 4.1% fungi and so on. Ten canals presented no microbial growth. Conclusions: The prevalence of bacteria and fungi found in 100 root canals is the prevalence of the microbial genera in primary and secondary endodontic infection. Peptostreptococcus spp was the most predominantly isolated microbial genera, followed by Streptococcus spp (14.2%), Porphyromonas spp (12.2%), E. faecalis (9.6%), Staphylococcus salivarius (8.6%), Prevotella spp (8.1%), Lactobacillus spp (7.1%), Actinomyces spp (7.1%), Candida albicans (4.1%), Fusobacterium spp (3.6%) Veillonella spp (2.5%), Eubacterium spp (2.5%), Bacillus spp (2.0%), and Escherichial coli (1.6%) were other types of bacteria recovered.Öğe New method for measurement of surface areas of microleakage at the primary teeth by biomolecule characteristics of methilene blue(2005) Yavuz, I.; Aydın, A. Haluk; 0000-0001-6953-747XThis study was planned to investigate the feasibility of a different approach as an alternative to the methods for determining the microleakages caused by the dental restorations. Several different methods are currently being implemented to determine the microleakage. Our method, utilizes the molecular characteristics of the methylene blue in which pH adjusted to 6.98, and the surface area covered by the methylene blue dye adsorbed in the areas where leakages have occured subsequent to the thermal conversion similar to the traditional methods. Within the framework of this study, 20 primary molars were divided into two groups, and restorations were made in one group with the glass ionomer cement plus amalgam while the other group of teeth was treated with glass ionomer cement and composite. These two groups were evaluated for surface area measurements using the Mann-Whitney U test with SPSS 10.0 statistical package, and were found to be statisticaly different (p<0.001). It is therefore concluded that this method may be used as a new technique for the determination of microleakage and that it may even be further developed.Öğe New technique: Measurement of microleakage volume in the marginal gaps of the dental restorations(2005) Yavuz, I.; Aydın, A. Haluk; Ülkü, Refik; Dülgergil, Türksel Çoruh; Akdaǧ, Mehmet Zülküf; 0000-0001-6953-747XThis study investigates the feasibility of a different approach to determining the microleakage volume associated with dental restorations and the relative marginal adaptation deficiency of dog, bovine and human primary teeth in in vitro conditions. It was also researched the appropriateness of using dog and bovine teeth in in vitro studies instead of human teeth. Our method utilizes the molecular characteristics of methylene blue (MB). Within the framework of this study, 60 permanent teeth (20 human, 20 dog and 20 bovine) were used. Class V cavities were prepared in all human, dog and bovine primary teeth and all restorations were made by Composite. These groups were evaluated statistically for dye penetration and microleakage volume measurements using Kruskal-Wallis non-parametric test (p>0.05) and One Way ANOVA, both of which indicated no statistically significant differences (p>0.05). This preliminary investigation showed that the new microleakage volume measurement method might be a valuable tool for the in vitro study of microleakage dynamics around dental restorations. However, this method can be used as a new technique for the determination of microleakage volume. As a result of this study; dog and bovine teeth can be used instead of human teeth.Öğe A novel INDEL mutation in the EDA gene resulting in a distinct X- linked hypohidrotic ectodermal dysplasia phenotype in an Italian family(Wiley-Blackwell, 2016) Callea, M.; Nieminen, P.; Willoughby, C. E.; Clarich, G.; Yavuz, I.; Vinciguerra, A.; Di Stazio, M.[Abstract Not Available]Öğe The possible usability of three-dimensional cone beam computed dental tomography in dental research(Iop Publishing Ltd, 2017) Yavuz, I.; Rizal, M. F.; Kiswanjaya, B.The innovations and advantages of three-dimensional cone beam computed dental tomography (3D CBCT) are continually growing for its potential use in dental research. Imaging techniques are important for planning research in dentistry. Newly improved 3D CBCT imaging systems and accessory computer programs have recently been proven effective for use in dental research. The aim of this study is to introduce 3D CBCT and open a window for future research possibilities that should be given attention in dental research.Öğe Prevalence of Traumatic Dental Injuries and Associated Factors Among 8 to 12-years-old Schoolchildren in Diyarbakir, Turkey(Wolters Kluwer Medknow Publications, 2017) Tumen, E. C.; Yavuz, I.; Kayd, S.; Uysal, E.; Tumen, D. S.; Ay, Y.; Basaran, G.Background and objectives: This study aimed to assess the prevalence of traumatic injuries of the permanent incisors in public primary schoolchildren from 8 to 12 years old in South-Eastern Anatolia, Turkey. Additionally, the relationship between traumatic dental injuries, parents' education level, family income, size of incisal overjet and the presence of anterior open bite were examined. Materials and methods: Data were collected through oral examinations and structured interviews, and included socio-economic indicators. A total of 2907 children of both genders (1498 boys, 1409 girls) were included in the study. The response rate was 97%. Results: The prevalence of dental injuries was 4.6% (n = 135). The highest frequency of trauma in permanent teeth was observed at the age of 12 (8%). Boys experienced more dental injuries than girls, 5.9% and 3.3% (p = 0.001), respectively. The most commonly reported cause of injuries to the permanent incisors was falls (71.8%), followed by collision with objects or people (17.8%). Maxillary central incisors were the most affected by dental injuries (154, 84.6%). The most common crown fracture was in enamel only (67.58%) followed by crown fracture of enamel and dentin (22.52%). Conclusion: Socio-economic indicators and parents' level of education were not statistically significantly associated with the occurrence of traumatic dental injuries. Factors associated with increased risk of dental injuries in permanent teeth were age, gender, having an incisal overjet greater than 5mm and anterior open bite.Öğe The reliability of microleakage studies using dog and bovine primary teeth instead of human primary teeth(Ariesdue Srl, 2013) Yavuz, I.; Tumen, E. C.; Kaya, C. A.; Dogan, M. S.; Gunay, A.; Unal, M.; Toptanci, I. R.Aim This was to investigate if dental restorations on human, dog and bovine primary teeth are equatable for microleakage analysis, and the respective marginal adaptation deficiency in in vitro conditions. Materials and methods In order to determine the level of microleakage in Class V polyacid-modified composite restorations of human, dog and bovine primary teeth, samples were evaluated by dye-leakage method in sections of the inner area of the restorations. Results We found no leakage in 6 out of 10 (60%) human restorations, in 7 out of 10 (70%) of dog and in 7 out of 10 (70%) of bovine teeth. The levels of dye-microleakage were tested with Kruskal-Wallis one-way variant analysis method. The relative leackage differences were not statistically significant among all species (p>0.05). Conclusion We concluded that dog and bovine primary teeth might be suitable for in vitro studies instead of human ones.Öğe REVEAL BY BIOTECHNOLOGICAL EQUIPMENT TO THE BILATERAL NONFUNCTIONAL SUBMANDIBULAR GLANDS IN ECTODERMAL DYSPLASIA(Taylor & Francis Ltd, 2008) Yildirim, M.; Oktay, M. F.; Ozmen, C.; Yavuz, I.; Topcu, I.We reported a different presentation of ectodermal dysplasia in which bilateral submandibulary glands were nonfunctional. We also reviewed the literature about the ectodermal dysplasia and related submandibular gland abnormalities. In this case report a 22-years-old female with ectodermal dysplasia is presented, complaining of dryness of her mouth, difficulty of chewing, dysphagia and recurrent upper respiratory tract infections. Further investigations consisted of an ultrasound scan fit and small size submandibular salivary glands. Computed tomography confirmed that showed normal left and right parotid glands and small that both submandibular glands were hypoblastic. A 99mTc-pertechnetate scintigraphy showed normal uptake in the parotid glands. However, no functioning submandibular, glands were shown. Although the submandibular gland abnormalities can be rarely seen in ectodermal dysplasia, to our knowledge, this is the first report which presents nonfunctioning submandibular glands in an ectodermal dysplasia case.
