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Öğe Association between saliva quantity and content parameters with caries intensity levels: A cross-sectional study among subcarpathian children(Association of Support to Oral Health Research (APESB), 2019) Bilyschuk, Liubov M.; Andrii, Keniuk; Goncharuk-Khomyn, Myroslav; Yavuz, İzzetObjective: To evaluate saliva quantity and content parameters among children of 7 and 12 years old, who permanently living on the territory of Subcarpathia with the registered territoryassociated fluoride deficiency in the water, and their association with the caries status of pediatric patients. Material and Methods: The study sample was formed of 48 children (22 of 7 years old and 26 of 12 years old). The content of calcium in the oral liquid was determined by the ocresolphthalein complexone method. Estimation of concentration rate and fluoride activity in the oral liquid was carried out by using the ion-selective electrode ELIS-131 F and ionometer EV-74. The content of inorganic phosphorus in saliva was determined using the phosphorus reaction with molybdic acid. Results: Among all study samples, 18.8% were registered with low caries intensity level (DMF = 1.55 ± 0.16), 33.3% with moderate caries intensity level (DMF = 3.94 ± 0.29), and 47.9% with high caries intensity level (DMF = 9.05 ± 1.11). During the comparison of calcium content and mineralization coefficient values between children with low and high caries intensity levels registered difference was statistically significant (p<0.05), while for salivary flow rate parameter such difference was no significant (p>0.05). Between children with normal salivary flow rate, and children with a lowered salivary flow rate there was no statistical difference in such parameters as fluoride concentration, calcium content, phosphorus content and calcium-phosphorus balance (p>0.05). Conclusion: Caries intensity levels were more statistically associated with parameters of calcium content in saliva and related mineralization coefficient, rather than with the average salivary flow rate.Öğe Cleidocranialdysplasia. Amolecularandclinicalreview(2018) Fortunato, Leonzio; Yavuz, İzzet; Plotino, Gianluca; Avendano, Andrea; Callea, Michele; Grande, Nicola Maria; Rizal, Mochamad FahleviCleidocranial dysplasia (CCD) is a rare autosomal dominant disorder characterized by skeletal and dental abnormalities primarily, short stature, aplasia or hypoplasia of clavicles, open fontanelles and supernumerary teeth. Heterozygous mutations of the runt-related transcription factor 2 (RUNX2) gene have been found in approximately 60-70% of cases,leaving a large number of cases with no defined genetic cause which ledus to delve into molecular mechanisms underlying CCD and thus to detect potential target genes to be explored in these patients. In this review,we also highlight very broadly the phenotypic characteristics of previously reported patients with CCD.Öğe Comparison of bacterial load parameters in subgingival plaque during peri-implantitis and periodontitis using the RT-PCR method(University of Zagreb, 2020) Nastych, Oksana; Goncharuk-Khomyn, Myroslav; Foros, Anatoliy; Cavalcanti, Alessandro; Yavuz, İzzet; Tsaryk, VladyslavObjective: To estimate the actual parameters of bacterial load in subgingival plaque during periodontitis and peri-implantitis pathologies using the RT-PCR (real-time polymerase chain reaction) method and evaluate their associations with clinical periodontal indicators. Materials and Methods: Five different groups of subjects were selected according to a formulated design of the study: with mild/ moderate periodontitis, with severe periodontitis, with peri-implantitis, healthy periodontal group and healthy peri-implant group. Subgingival plaque samples were formed with paper points inserted in the pocket/sulcus area for 30 seconds. A standardized test the “ParodontoScreen” was provided for identification of target opportunistic pathogens (A. actinomycetemcomitans, P. gingivalis, T. forsythia, P. intermedia, T. denticola) by the RT-PCR. Results: Bacterial load parameters demonstrated a significant tendency towards an increase within periodontitis progression and during the presence of peri-implantitis pathology. Each targeted mean bacterial load level was statistically associated with periodontitis or peri-implantitis pathology (p < 0, 05) according to the provided univariate analyses and upon condition that bacterial load parameters of healthy sites were used as reference for equiparation. The highest correlation values were found between periodontal probing depth and bacterial load parameters of A. actinomycetemcomitans (r=0, 37; p < 0, 05) and P. gingivalis (r=0, 28; p < 0, 05); and also between clinical attachment loss and bacterial load values of A. actinomycetemcomitans (r=0, 38; p < 0, 05) and P. gingivalis (r=0, 24; p < 0, 05). Conclusions: Periodontitis and peri-implantitis are associated with the same microbial pathogens even though the distribution pattern of their bacterial load and detection frequency parameters registered with RT-PCR could be distinct and linked to the individual patient-related conditions and the severity stage of pathology.Öğe Ectodermal dysplasia: A retrospective evaluation of the clinical findings of forty-four cases in the 0-16 years age(Uluslararası Diş Araştırmaları Birliği, 2022) Akleyin, Ebru; Sarıyıldız, Cansu Osmanoğulları; Yavuz, İzzet; Adıgüzel, ÖzkanAim: The aim of this study was to review the craniofacial anomaly results of children diagnosed with ectodermal dysplasia (ED) and to identify the oral requirements of ED cases. Methodology: The data of this study were obtained by taking clinical examinations and radiographs on forty-four (44) children (22 females and 22 males), 0-16 years aged, who were admitted to the Dicle University, Faculty of Dentistry due to dental problems and were diagnosed with ED. The number of affected siblings was ascertained, and systemic findings were evaluated. Malformations in the hair, nails, nose, skin, lips, and teeth were clinically examined. Results: The most common clinical findings were sparse hair, dry skin, sweating problems, respiratory difficulty, saddle nose, a history of fever, hearing loss, and deformation in the nails. In the intraoral and radiological examinations, findings were evaluated of conical teeth, protuberant lips, prosthetic rehabilitation, impacted teeth, and abnormal root resorption. The rates of ED in the siblings of the ED cases were determined as 39.2% in the siblings of male cases and 37.9% in the siblings of female cases. Conclusion: The frequency rates of the anomalies seen in ED obtained in this study can be considered important as a guide for further studies of individuals with ED. When multiple missing teeth and conical teeth are encountered, the dental practitioner should investigate whether or not there are other symptoms of ED, and it must not be forgotten that the dentist may be the first step in the diagnosis of this genetic irregularity.Öğe Effect of silver diamine fluoride application on fluoride concentration in saliva(Institute of Physics Publishing, 2018) Widianti, T. A.; Bahar, Armasastra; Maharani, Diah Ayu; Tümen, Emin Caner; Yavuz, İzzetSilver diaminefluoride can increase fluoride concentration in saliva, facilitate remineralization, and increase the bioavailability of fluoride in saliva. The purpose of this study was to analyze the difference in fluoride concentration in saliva before and after silver diaminefluoride application on enamel. Stimulated saliva of four subjects was collected, and the concentration of fluoride was measured. The results showed that there were significant differences in the fluoride concentration (p<0.05) before, immediately after, and one hour after silver diaminefluoride application on enamel. It can be concluded that fluoride concentration reached its peak immediately after silver diamine fluoride application on enamel and that it had returned to the baseline one hour after application.Öğe Efficacy of mouth rinse formulation based on cetylpyridinium chloride 0.1% in the control of dental calculus buildup(Innovare Academics Sciences Pvt. Ltd, 2017) Maharani, Diah Ayu; Ramadhani, Alia; Adiatman, Melissa; Wimardhani, Yuniardini Septorini; Kusdhany, Linda; Rahardjo, Anyon; Yavuz, İzzetObjective: This study aimed at comparing the antiplaque, anticalculus, and antigingivitis potentials of a mouth rinse containing essential oil, alcohol, zinc, and fluoride with a mouth rinse containing cetylpyridinium chloride (CPC) 0.1% over 1-, 2-, and 3-month periods. Methods: This study was a double-blind, parallel randomized clinical trial with a 3-day run-in phase. Respondents were asked to gargle twice daily with 15 ml of mouth rinse for 30 seconds after brushing teeth. Respondents were 80 females with a mean age of 21 years, and a single dental examiner was employed throughout the study to decrease the variance. Prophylaxis was performed for all respondents before the intervention. Three mouth rinses were tested: Group 1 with the mouth rinse containing CPC 0.1%, Group 2 as the negative control, and Group 3 as the positive control with a mouth rinse containing alcohol. Evaluations were conducted by plaque index, gingival index, calculus index, and CariScreen examinations. Results: The clinical trial showed that the mouth rinse with alcohol and the mouth rinse containing CPC 0.1% were effective in inhibiting bacterial buildup (antiplaque) and have anticalculus properties, but with no statistically significant antigingivitis effect. Conclusion: It was found that the mouth rinse containing alcohol has similar effectiveness with CPC 0.1% mouth rinse, but side effects, such as a burning sensation, were reported in the alcohol-containing mouth rinse. © 2017 The Authors. Published by Innovare Academic Sciences Pvt Ltd.Öğe Ektodermal displazili hastalarda protetik yaklaşımlar(2011) Ülkü, Başkan S.Zelal; Yavuz, İzzetUluslararası Ektodermal Displazi Kuruluşu (NFED) ektodermal displaziyi iki veya daha fazla sayıda ektoderm orijinli (deri, tırnak, saç, ter-yağ bezleri ve diş gibi) dokunun gelişim bozukluğuyla karakterize, nadir görülen kalıtsal bir hastalık olarak tanımlamaktadır. Hastalığın neredeyse 200’e yakın tipi tanımlanmıştır. Bu sendromun dental özelliği, süt veya sürekli dişlenmede anadonti veya hipodonti, hipoplastik konik dişler ve az gelişmiş alveolar sırtlar olarak tanımlanmaktadır. Kalıtsal/gelişimsel hastalık gösteren erken yaştaki hastalarda prostodontistin kompleks fonksiyonel ve estetik restoratif değişiklikler yapması gerekebilir. Dentisyonu normal gelişmeyen ED vakalarında hastaların yaşının çok genç olması nedeniyle protetik tedavi uygulaması önemli bir rol oynar. Aynı zamanda fizyolojik ve psikososyal nedenlerden dolayı da bu hastaların tedavisinin en erken dönemde yapılması çok önemlidir. Hastaya uygun kesin tedavi planı seçenekleri sabit protezler, hareketli bölümlü protezler, implant destekli protezler, tam protezler ve overdenture protezleri veya bunların kombinasyonlarını içermektedir. Bununla birlikte maddi kısıtlamalar veya diğer öncelikler bazen hastaya en uygun tedaviyi seçmeyi engelleyebilir. Tedavi amacı, hastalarda yatay ve dikey iskeletsel ilişkileri ve yüz estetiğini sağlayabilmek için en uygun prostodontik başlangıç noktasını yaratabilmektir. Bunun içinde tedaviyi yapacak olan hekimin hastayı, pedodontik, ortodontik, cerrahi ve protetik yönden değerlendirebilecek bilgiye sahip olması ve hastayla yakın ilişki kurabilmesi gereklidir. Bu derlemede, ED’li hastaların fonksiyonel ve estetik ihtiyaçlarını karşılayacak protetik tedavi seçeneklerinin anlatılması amaçlanmıştır.Öğe Ektodermal displazili olgularda klinik ve radyolojik bulguların incelenmesi(Fırat Üniversitesi Tıp Fakültesi, 2019) Doğan, Mehmet Sinan; Ataş, Osman; Yavuz, İzzet; Tekin, SametAmaç: Ektodermal displazi; deri, tırnak, saç, ter bezleri ve diş gibi ektoderm kaynaklı dokuları etkileyen ve nadir olarak rastlanan kalıtsal bir hastalıktır. Bu çalışmada fakülte hastanemize başvuran ektodermal displazili olgulardaki; sistemik ve dental bulguların klinik ve radyolojik olarak değerlendirilmesi amaçlanmıştır.Gereç ve Yöntem: Çalışmamızda 2006-2017 yılları arasında Dicle Üniversitesi Diş Hekimliği Fakültesi hastanesine diş eksikliği şikayetiyle başvuran, 49 ektodermal displazi olgusu retrospektif olarak değerlendirildi. Klinik değerlendirmede saç, tırnak, deri, diş, burun, ter bezleri ve benzeri malformasyonlar incelendi. Radyolojik muayenede; geleneksel radyografi ve konik ışınlı bilgisayarlı tomografi kullanılarak diş germleri, çene kemiği vediş köklerine bakıldı.Bulgular: Çalışmamızda yaş ortalaması 11,9±4,6 olan, 25’i kadın (%51,1), 24’ü erkek (%48,9) toplam 49 hasta değerlendirildi. Çalışmadaki ED’lihastaların oral bulguları ile ilgili olarak; %100 (n =49) diş eksikliği, %100 (n =49) mandibular protrüzyon ,%75,51 (n =37) konik diş, %6,12 (n =3)kök şekil anomalileri görülmüştür. Klinik muayenesinde ise terleme problemi %77.55 (n =38), saç-kıl anomalisi %95.91 (n =47), anormal parmak vetırnaklar %83.67 (n =41) belirlendi.Sonuç: ED’nin temel bulguları oral ve maksillofasiyal bölgede oluştuğundan, estetik ve çiğneme problemleri ortaya çıkmaktadır. Bu nedenle dişhekimliğinde multidisipliner tedavi gerektiren özel bir yere sahiptir. Bu hastalarda yaşam kalitesini artırmaya yönelik olarak tıp ve diş hekimlerininkoordineli çalışması oldukça önem kazanmaktadır.Öğe Estudio clínico y molecular en una familia con displasia cleidocraneal(Sociedad Argentina de Pediatria, 2017) Callea, Michele; Fattori, Fabiana; Bertini, Enrico Silvio; Yavuz, İzzet; Bellacchio, Emanuele; Avendaño, AndreaCleidocranial dysplasia is an uncommon bone dysplasia with an autosomal dominant inheritance pattern characterized by short stature, large fontanels, midface hypoplasia, absence or hypoplasia of clavicles and orodental alterations. This is produced by mutations in the RUNX2 gene located at 6p21.1. We report two male adolescents (cousins), with cleidocranial dysplasia who presented a heterozygous missense mutation (c.674G>A, p.R225Q) in the RUNX2 gene, characterized by severe phenotype, such as absent clavicles, but with variation in the delayed fontanel closure, dental abnormalities (anomalies in shape and number) and scoliosis, thus demonstrating intrafamilial variation in these patients with the same genotype.Öğe Evaluation of ectodermal dysplasia(Elsevier (Singapore) Pte Ltd, 2006) Başkan, Zelal; Yavuz, İzzet; Ülkü, Refik; Kaya, Sadullah; Yavuz, Yasemin; Başaran, Güvenç; Adıgüzel, Özkan; Özer, Torun; 0000-0001-6953-747X; 0000-0001-6953-747X; 0000-0001-6089-3013This case series report outlines possible cranio-maxillofacial deformation consequences associated with ectodermal dysplasia (ED) and embryonic malformations, including dental agenesis. Also described are the oral aspects and rehabilitation. A total of 14 ED patients (7 males and 7 females, aged 5-45 years) underwent clinical examination before assessment and treatment. Lateral cephalometric radiography, Steiner's analysis, and respiratory capacity tests were performed. Most of the patients had sparse or absent hair, a short face with an unusual facial concavity, a maxillary retrusion, and a relative mandible protrusion. Depending on age and orthopedic abnormalities, patients were treated with prosthodontic and orthodontic approaches or implant treatment. Therapists should take a comprehensive and multidisciplinary approach with these patients to improve their dental, masticatory, growth, and orthognathic conditions, as well as esthetic appearance.Öğe Identification of the main risk factors for the development of disorders of occlusive relationships.(Harran University, 2024) Shkarin, Vladimir; Yarygina, Elena; Alekseevna, Makedonova Yuliya; Dyachenko, Denis; Gavrikova, Lyudmila; Yavuz, İzzetIntroduction: Violations of occlusive relationships are an urgent problem in dental practice due to the high prevalence, complexity of diagnosis and treatment, as well as the connection with common somatic diseases. These pathologies reduce the quality of life of patients and complicate the process of medical rehabilitation. Prevention aimed at early detection of risk factors is especially important. The purpose of this study is to identify the main risk factors for the development of disorders of occlusive relationships. Materials and methods: A randomized controlled trial was conducted with 120 patients aged 18 to 44 years. The study did not include patients with acute infectious diseases, decompensated chronic diseases, oncology, mental disorders and periodontal inflammation. The assessment included clinical examination, cone beam computed tomography (CBCT), electromyography (EMG), ultrasound examination of the temporomandibular joint (TMJ) and occlusion analysis. Methods of 3D modeling and analysis of the symmetry of the skull were used, as well as the Hamburg test to assess the functional state of the TMJ. The results of the clinical examination were subjected to a hierarchical cluster analysis. Results and discussion: Based on the results of the survey, a group of key risk factors affecting the development of occlusive disorders was identified. The analysis of the data showed that the most significant components are the muscular, articular and jaw complexes, including electromyographic parameters, the size of the articular gap and occlusal contacts. The average value of the Hamburg test among patients was 3.79±0.73 points, which indicates a high prevalence of TMJ dysfunction. Cluster analysis made it possible to identify three main groups of risk factors, including muscle, joint and dental signs. Conclusion: The identification of risk factors for the development of occlusive disorders plays a key role in improving the diagnosis and treatment of patients. The use of cluster analysis and modern technologies, such as 3D modeling and artificial intelligence, makes it possible to increase the effectiveness of prevention and treatment of this pathology.Öğe Key aspects of dental diagnostics and treatment specifics in ectodermal dysplasia patients: Comprehensive literature review(Termedia Publishing House Ltd., 2020) Yavuz, İzzet; Goncharuk-Khomyn, Myroslav; Cavalcanti, Alessandro Leite; Boykiv, Alina B.; Nahirny, YaroslavIntroduction: Pathogenesis of ectodermal dysplasia (ED) is explained by alterations occurring within derivates of ectoderm, caused by different genetic violations. Objectives: The aim of this study was to provide critical comprehensive literature review considering diagnostic and treatment specifics among dental patients with ED. Material and methods: Comprehensive literature search was provided via PubMed database (https://pubmed. ncbi.nlm.nih.gov/) and Google Scholar search engine (https://scholar.google.com/). Systematized number of publications was evaluated as a subject of manual content analysis, categories of which included dental diagnostic and treatment aspects of patients with ED. . Results: Treatment approaches for remaining deciduous and permanent teeth under the condition of future prosthodontic rehabilitation planning differ in numbers of publications dedicated to the topic of dental care provision among ED patients. Such non-consistency could be explained by diversities in described prosthetic rehabilitation protocols, and initial variations of teeth’s form, structure, developmental stages, and their overall quantity registered during primary examination of ED dental patients, including possible alterations in enamel integrity, dispersions in pulp chamber volume, caries intensity levels, changes in root formation stages, and eruption phases during ED. Conclusions: The most prominent dental and oral signs of ED that potentially could be used as criteria for diagnostics with varying degree of diagnostic significance, include oligodontia, delayed eruption and development of teeth, changed tooth crown and/or root morphology, decreased salivary function, cleft lip and/or palate. However, there is no unified algorithm of ED dental patients’ rehabilitation, and planning of such should consider a number of initial clinical situation’s factors, ED manifestations, individual functional prognosis, and esthetic demands.Öğe Modern methods of diagnosis of occlusive imbalance in patients with temporomandibular myofascial pain syndrome(Harran University, 2024) Shkarin, Vladimir; Yarygina, Elena; Alekseevna, Makedonova Yuliya; Dyachenko, Denis; Gavrikova, Lyudmila; Yavuz, İzzetIntroduction. In recent years, there has been a growing interest in digital methods for diagnosing occlusive imbalance both in Russia and abroad. The development of technologies in this area opens up new prospects for improving the diagnosis and treatment of dental diseases. The purpose of this study is to analyze existing digital methods and devices for diagnosing occlusive imbalance, identify their advantages and disadvantages, and assess the prospects for their implementation in clinical practice. Materials and methods: To achieve this goal, a systematic review of 40 scientific publications covering the period from 2016 to 2024 was conducted. The study includes both domestic and international sources from leading scientific electronic libraries and databases. Data on various types of digital devices such as strain gauges, piezoresistive and piezoelectric transducers, pressure sensors and fiber optic sensors are analyzed. Methods of index evaluation of occlusal contacts have also been studied. Results and discussion: The analysis showed that existing digital technologies for the diagnosis of occlusive imbalance have significant potential to improve the accuracy and effectiveness of diagnosis. Load cells, piezoresistive and piezoelectric transducers, as well as pressure sensors and fiber optic sensors provide various approaches to measuring the occlusion force. Despite their high sensitivity and accuracy, the implementation of these technologies faces challenges such as the complexity of equipping clinics and the insufficient level of digital competencies among doctors. Conclusion: Digital diagnostic technologies for occlusal imbalance have significant potential to improve dental practice. However, for the successful implementation of these methods, it is necessary to overcome the existing difficulties associated with equipment and training of specialists. Further efforts in the field of digital technology development, process automation and advanced training of dentists can contribute to more effective diagnosis and treatment of occlusion disorders.Öğe A new biological approach to guided bone and tissue regeneration(2013) Montanari, Marco; Callea, Michele; Yavuz, İzzet; Maglione, MicheleThe purpose of this study was to determine the potential of platelet-rich fibrin (PRF) membranes used for guided bone and tissue regeneration. A patient with insufficient alveolar ridge width in aesthetic zone was enrolled. The patient' s blood was centrifuged to obtain PRF membranes. Autogenous bone graft was mixed with bovine hydroxyapatite, PRF particles and applied to fill the defect. Five PRF membranes were placed over the bone mix. After 4 months a cone-beam CT was performed to evaluate bone regeneration. The use of PRF as cover membrane permitted a rapid epithelisation and represented an effective barrier versus epithelial cell penetration. After 4 months the site appeared precociously healed and the bone volume increased. This new approach represents a predictable method of augmenting deficient alveolar ridges. Guided bone regeneration with PRF showed limitation compared with guided bone regeneration using collagen membrane in terms of bone gain. The association of collagen membrane and PRF could be a good association.Öğe A new phenotypic variant in cleidocranial dysplasia (CCD) associated with mutation c.391C>T of the RUNX2 gene(BMJ Publishing Group, 2012) Callea, Michele; Fattori, Fabiana; Yavuz, İzzet; Bertini, Enrico; 0000-0002-0683-1310The RUNX2 gene is a physiological regulatory gene implicated in the development of cleidocranial dysplasia (CCD). A 13-month-old child presented with clinical features of CCD. At the age of 3 years the diagnosis was corroborated by clinical genetic assessment and DNA analysis, revealing a missense mutation p.R131C (c.391C>T) in RUNX2. At the age of 8 years the child was found to have a unique dental phenotype, represented by lack of supernumerary teeth and congenital absence of one tooth. A simple therapeutic approach was adopted, consisting of interceptive orthodontic treatment. The presence of this specific missense mutation in RUNX2, associated with the lack of typical supernumerary teeth may suggest a phenotype-genotype association.Öğe Oral health and evaluation of skeletal development in children with renal disease(2008) Kaya, Sadullah; Hamamcı, Nihal; Yavuz, İzzet; Adıgüzel, Özkan; Tümen, Emin CanerThe aim of this study was to monitor the oral health of chidren with chronic renal disease and skeletal development in children with renal disease. Thirty-six children (aged 3-13 years) were given a ffill clinical and radiological dental examination to evaluate skeletal development and tooth changes. After the first diagnosis and careful examination, enamel defects were clinically detected in a total of 11 children (30.5%). Of these, eight children clinically affected (22.2% of all those examined) exhibited localized hypoplasia of the primary canines, which was determined in only 3% of healthy control children. This increased prevalence is probably due to disordered calcium and phosphate metabolism. Chronological ages were recorded and hand-wrist radiographs were taken in our clinic. Accordingto our results, skeletal developments is slower than chronological development and this is statistically significant. Dental and medical cafe should be closely integrated for children with renal disease in order to avoid undesirable dental sequelae.Öğe Oral manifestation of Goltz-Gorlin syndrome in a young girl(BioMed Central Ltd., 2012) Callea, M.; Yavuz, İzzet; Deroma, Laura; Montanari, Marco; Clarich, Gabriella; Maglione, Michele; Albertini, Enrico[No abstract available]Öğe Oral manifestations in a boy with X-linked reticulate pigmentary disorder(BioMed Central Ltd., 2012) Callea, M.; Maglione, Michele; Yavuz, İzzet; Deroma, Laura; Willoughby, Colin E.; Tadini, Gianluca[No abstract available]Öğe Post-trauma root fracture in teeth with incomplete root development: A case report(Innovare Academics Sciences Pvt. Ltd, 2017) Doğan, Mehmet Sinan; Maharani, Diah Ayu; Kusdhany, Lindawati S.; Adiatman, Melissa; Yavuz, İzzetObjective: Oblique root fractures consist of multiple, angled fracture lines extending from the root canal to the periodontal membrane along the long axis of the tooth. Oblique root fractures are injuries with poor prognosis which are rarely observed in teeth in which the root development is complete. Methods: A clinical and radiological inspection was performed of an eight-year-old patient who presented at our clinic for dental trauma. Luxation and oblique sectional root fractures in the maxillary incisors were found. The patient’s root development was incomplete. He was treated with dental reposition. Fixation to the adjacent primary canine teeth was carried out using a 0.4 mm full circle orthodontic wire for fractured teeth with a semi-rigid splint. Stabilization of the teeth was ensured to protect the vitality of the fractured teeth. A splint was inserted under local anaesthesia and removed a month later. Results: The absence of pathological symptoms was determined radiologically and clinically. It was shown during a radiological examination of the patient a year later that root development inthe teeth with a root fracture had continued. There were no pathological complications. Conclusion: The current study finding of high recovery potential in young permanent teeth with root fracture is supported by those of other studies in the literature. Recovery in this case was successful because the patient presented timeously at the clinic after the trauma, there was a lack of infection, and the splint was only in situ for a month.Öğe The protective effect of melatonin and Ganoderma lucidum against the negative effects of extremely low frequency electric and magnetic fields on pulp structure in rat teeth(Taylor and Francis Ltd., 2017) Doğan, Mehmet Sinan; Yavaş, Mehmet Cihan; Günay, Ayşe; Yavuz, İzzet; Deveci, Engin; Akkuş, Zeki; Tanık, Abdülsamet; Akdağ, Mehmet ZülküfBackground/aim: The aim of this study was to determine whether Extremely low frequency electric and magnetic field (ELF-EMF) had any harmful effects on dental pulp tissue and examine histologically whether melatonin (MLT) and Ganoderma lucidum (GL) play a protective role against these harmful effects. Material and method: A total of 56 adult, male Wistar Albino rats were used in the study. The rats were separated into 8 equal groups and were exposed to ELF-EMF, generated by high voltage source, for 8 hours/day for 26 days–Groups I, II and III and for 52 days-Groups V, VI and VII. For sham-control groups (Groups IV and VIII for 26 and 52 days), rats were placed into same experimental set-up as exposure groups and same procedure was applied except ELF-EMF exposure. GL (20 mg/kg/day) and MLT (10 mg/kg/day) were administered by oral gavage and the intraperitoneal route respectively. At the end of the study, the rats anterior teeth were examined immunohistochemicaly using vimentin and vascular endothelial growth factor (VEGF). Results: Degeneration in the odontoblast cells, inflammatory cell infiltration, dilatation of the blood vessels and haemorrhagic changes were determined in the pulp of the rats in Groups I and V. A statistically significant difference was determined in the groups treated with MLT and GL (p < 0.05). Conclusion: It was determined that exposure to ELF-EMF induced histological changes in the dental pulp of rats, the using of MLT and GL could have a protective effect against these effects.