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    Clinical and laboratory presentation of typhoid fever
    (2001) Yaramis A.; Yildirim I.; Katar S.; Özbek M.N.; Yalçin I.; Tas M.A.; Hosoglu S.
    A total of 314 children with clinical and/or laboratory diagnosis of typhoid fever admitted to the Dicle University Hospital pediatric infectious diseases ward were reviewed for demographic data such as age, sex, clinical features, and results of laboratory tests. There were 187 male and 127 female patients, with a mean age of 9.6 years ranging from 6 months to 16 years. Eleven of all the children were less than one year of age, while 23 were under the age of five years. Predominant symptoms were fever, abdominal pain, vomiting, and headache. Hepatomegaly was almost twice as frequently observed as splenomegaly. Common clinical signs of typhoid fever in adults such as relative bradycardia and spots were seldom documented. A febrile convulsion was the presenting symptom in nine of the patients, all of whom were under the age of five years. Intestinal perforation was present in five of the patients. Antibiotic susceptibility tests in 67 cases revealed resistance rates of 17% for ampicillin, 5% for trimethoprim-sulfamethoxazole, 4% for ceftriaxone, and 6% for sulbactam-ampicillin. No resistance was detected against the quinolones and chloramphenicol. Elevated serum alanine and aspartate aminotransferase (50 > /U/L) levels were observed in 32% of our patients. At presentation, 38% of all patients were anemic (Hb <12 g/dl), 10% were thrombocytopenic (<105/mm3). Except the two bacteriologically confirmed typhoid fever patients died during the period of observation, all patients survived from their severe illness completely.
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    The evaluation of gastroesophageal reflux incidence in children with various symptoms by cintigraphy [3]
    (1998) Yaramis A.; Gurkan F.; Haspolat K.; Dikici, Bünyamin; Derman O.; Soker M.; Yilmaz S.
    [No abstract available]
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    Intravenous immunoglobulin in the treatment of Guillain-Barre syndrome
    (1997) Elevli M.; Yaramis A.; Soker M.; Haspolat K.; Gunbey S.
    [No abstract available]
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    Microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure associated with acute brucellosis
    (2001) Söker M.; Devecioglu C.; Yaramis A.; Ipek S.; Özbek M.N.; Tüzün H.
    Microangiopathic hemolytic anemia and severe thrombocytopenia are rare in childhood brucellosis: there are few reported cases. We report our experience with a 9-year-old boy with brucella infection presenting at the onset as a microangiopathic hemolytic anemia, severe thrombocytopenia and acute renal failure with coexisting gastrointestinal bleeding and gross hematuria. Peripheral blood smear examination showed hemolytic anemia, thrombocytopenia, and leukopenia. Bone marrow aspiration specimen revealed hypercellularity, histiocytic proliferation, and hemophagocytosis of the typical features associated with Brucella infection. Results of agglutination tests for Brucella in CSF and serum were positive. The patient recovered completely after appropriate antimicrobial therapy (consisting of rifampin, doxycycline, gentamicin) and fresh-frozen plasma, platelet transfusion, and rehydration therapy. We suggest that brucellosis must be investigated when hemolytic uremic syndrome (HUS) like disease exists with no known etiology, especially in endemic countries.