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    Cranial duplication (Dicephalus) in a lamb
    (Tubitak Scientific & Technological Research Council Turkey, 2007) Unver, Ozkan; Kilinc, Mehmet; Ozyurtlu, Nihat
    A case of cranial duplication (Dicephalus) was described in a newborn lamb. The radiographic and macroscopic examination was performed after the cesarean section. The lamb's heads were not completely separated. A complete nasopharynx, oropharynx, laringopharynx, and normal tongue were present in each head. The lamb died shortly after birth.
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    Dose-dependent effects of propofol on expression ICAM-1 in rabbit aorta endothelial cells
    (Academic Journals, 2009) Ketani, M. Aydin; Kanay, Berna Ersoez; Ketani, Sennur; Unver, Ozkan; Kilinc, Mehmet
    The dose-dependent effects of propofol on expression intracellular adhesion molecule (ICAM-1) in rabbit aorta endothelial cells was examined. Twenty adult New Zeland albino rabbits were used in this study. One control and three experimantal groups were designed. In experimantal groups; for group I propofol was not applied, group II 0.5, group III 4.0 and group IV 8.0 mg/kg propofol were applied to rabbits by marginal ear vein. One hour after applying propofol, control and experimantal group rabbits were sacrificed and their aorta were removed. The sections were stained with APAAP immunohistochemical staining for evaluation using a light microscope. This marked ICAM-1 immunoreactivity was maintained in 8.0 mg/kg of propofol applied to rabbits of aorta endothelium, whereas mild stain was observed for other experimantal groups. The present study indicated that there is parallel relationship between endothelial cells ICAM-1 expression and different doses of propofol.
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    Effect of ovariectomy and female sex hormones administration upon gastric ulceration induced by cold and immobility restraint stress
    (Saudi Med J, 2007) Kurt, Dogan; Saruhan, Berna G.; Kanay, Zeki; Yokus, Beran; Kanay, Berna E.; Unver, Ozkan; Hatipoglu, Savas
    Objective: To investigate the protective effects of estrogen and progesterone administrations on gastric mucosal barrier of rats applied ovariectomy, cold and immobility stress. Methods: Seventy female Wistar rats, obtained from Medical Science Application and Research Center, Dicle University, Turkey on the year 2004, were divided into 10 separate groups (n=7). Nothing was applied to the animals of Group 1 (control); bilateral ovariectomy was performed on the animals of the Groups 2, 4, 5, 6, 7, 8, 9, and 10. Groups 5 and 6 was applied 5 mg/kg 17beta-estradiol and groups 7 and 8 was applied 10 mg/kg progesterone for 7 days. The animals in the Groups 9 and 10 were applied 2.5 mg/kg 17beta-estradiol and 5 mg/g progesterone during 7 days. The animals in the groups 3, 4, 6, 8 and 1 were exposed to cold and immobility stress for 4 hours at 4 degrees C. Results: The levels of mucus and phospholipids were decreased in the rats applied ovariectomy and stress as compared to the control groups (p<0.001). The increase determined the mucus and phospholipids levels in estrogen and progesterone administered rats as compared to stress applied group (p<0.001). While the cold and immobility stress causes important damages in gastric mucosa, estrogen and progesterone administrations has protective effects in ovariectomized rats. Conclusion: The estrogen and progesterone administration prevents the stress that caused decrease in the levels of mucus and phospholipids, thus females are more resistant to gastric ulcer rather than males due to their sex hormones.