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    Cesarean scar pregnancy: A tertiary center case series and literature review
    (Duzce University Medical School, 2015) Turgut A.; Özler A.; Goruk N.Y.; Tunç S.Y.; Başaranoğlu S.; Yalìnkaya A.
    Aim: To examine the characteristics, management and outcomes of cesarean scar pregnancies at a single tertiary obstetric centre over a three-year period. Method: A retrospective study was performed on 8 cases of cesarean scar pregnancy identified between January 2009 and June 2012 from the medical files. Results: The mean gestational age was 58.2 days (35-120). The average time for ?-hCG levels to return to normal values after treatment for cesarean scar pregnancy was 3.4 weeks (2-6). The mean number of previous cesarean sections was 1.9 (1-4) and the mean interval time after the last cesarean section was 20 months (10-48). Laparotomy with excision of the sac and primary repair (n=5) and methotrexate (n=3) were the modalities of management. Conclusion: Cesarean scar pregnancy is a potentially life-threatening complication of pregnancy that constitutes a diagnostic and therapeutic challenge. Decision on treatment modality should be determined on individualized basis depending on factors such as gestational age, ?-hCG levels, fetal cardiac activity, desire of future fertility and the experience and facilities available. Key words: Cesarean scar; complication; cesarean scar pregnancy; ectopic pregnancy. © 2012 Düzce Medical Journal.
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    Effects of adnexal torsion on the fallopian tube in rats: A histologic and immunohistochemical study
    (Science Printers and Publishers Inc., 2014) Tunç S.Y.; Ağaçayak E.; Yaman N.S.; Deveci E.; Kalkanli S.; Özler A.
    Objective: To investigate histopathological and immunohistochemical changes in the Fallopian tube structure following ovarian torsion. Study design: Thirty fertile, female, adult Wistar albino rats, weighing 200-220 g, were randomly divided into 3 equal groups (n=10): sham, torsion, and detorsion. In the torsion and detorsion groups, bilateral adnexal torsion (3-hour ischemia) was carried out. Bilateral adnexal detorsion (3-hour reperfusion) was performed in the detorsion group. Fallopian tube sections were stained hematoxylin and eosin, periodic acid-Schiff, Mallory-Azan and immunohistochemically-stained desmin, ? smooth actin, and CD68 antibodies. Results: In the sections of the ischemic group, degeneration of epithelium, loss of cilia, dilation of blood vessels, and hemorrhages were observed. Image analysis of the studied Fallopian section revealed a significant decrease in density of desmin in the torsion group. Moreover, strong positive cytoplasmic CD68 expression was observed in the torsion group. Conclusion: The use of effective antiinflammatory treatments may contribute to the conservative surgery in preservation of ovarian reserve and tubal structure. © Science Printers and Publishers, Inc.