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Öğe Can intravenous cyclophosphamide be used for steroid-dependent nephrotic syndrome?(Springer Verlag, 1997) Bircan, Z; Soran, M; Kervancioglu, M; Gonlusen, G; Tuncer, I[Abstract Not Available]Öğe The effect of alternate-day low-dose prednisolone on bone age in children with steroid-dependent nephrotic syndrome(Springer Verlag, 1996) Bircan, Z; Soran, M; Yildirim, I; Dogan, M; Sahin, A; Bilici, A; Danaci, M[Abstract Not Available]Öğe Growth hormone stimulation tests in chronic renal failure with metabolic acidosis(Blackwell Publishing Asia, 1998) Bircan, Z; Kervancioglu, M; Soran, M; Yildirim, IMetabolic acidosis is one of the possible causes of growth retardation in chronic renal failure (CRF). Data about the effect of metabolic acidosis on growth hormone (GPI) secretion in CRF are limited. A study was carried out on eight CRF patients, hospitalized because of severe metabolic acidosis, and eight age-matched prepubertal healthy short children. Growth hormone stimulation tests were done with L-dopa and clonidine before or during acidosis therapy and after the correction of metabolic acidosis. The levels of GH were measured by radio-immunoassay. The mean of the peaks of both tests were used for each patient and statistical significance was tested by Mann-Whitney U and Wilcoxon tests. No difference was found between the GH peaks of the two groups during acidosis and after the correction of acidosis (Wilcoxon test, P > 0.05). In view of this data it was concluded that metabolic acidosis has little effect on GH stimulation tests.Öğe Serum levels of carnitine, apolipoprotein A I, and apolipoprotein B in children with nephrotic proteinuria(Springer Verlag, 1996) Bircan, Z; Kaplan, A; Soker, M; Batun, S; Sahin, A; Soran, M[Abstract Not Available]Öğe Sialic acid in childhood renal diseases: Correlation with clinical and laboratory indices(Blackwell Science, 1998) Bircan, Z; Batun, S; Kervancioglu, M; Soran, M; Kaplan, A; Onur, H; Demir, FThere are many kinds of glycoproteins that have sialic acid residues and it has been reported that these are elevated in some renal diseases and their significance in the pathogenesis of several renal diseases has been investigated. In the present study the serum and urine levels of sialic acid were measured in healthy controls and in children with either poststreptococcal acute glomerulonephritis (PSAGN) or minimal change nephrotic syndrome (MCNS) to test if there is any correlation with clinical and laboratory indices. In PSAGN and MCNS patients the serum and urine sialic acid concentrations at onset and relapse were significantly different from healthy controls (Mann-Whitney U-test P < 0.005). There was not a significant correlation between the clinical severity, serum creatinine and complement C-3 levels and serum sialic acid concentrations in PSAGN patients. Also there was not a significant correlation between edema, serum albumin, IgG, transferrin, alpha-1-antitrypsin and serum sialic acid concentrations in MCNS patients. Although high serum and urine sialic acid levels were found in both PSAGN and MCNS patients, it does not have any clinical significance nor is it important as a diagnostic or prognostic marker.Öğe Two cases of nephrotic syndrome and tertian malaria in south-eastern Anatolia(Springer Verlag, 1997) Bircan, Z; Kervancioglu, M; Soran, M; Gonlusen, G; Tuncer, ITertian malaria is endemic in south-eastern Anatolia. As in Europe and America, in south-eastern Anatolia, an etiological agent is seldom identified in nephrotic syndrome, Two patients with Plasmodium vivax and nephrotic syndrome are described here. The possible relationship between Plasmodium vivax and nephrotic syndrome should be explored in children in endemic malarial regions.