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  • [ X ]
    Öğe
    The accuracy and validity of a weekly point-prevalence survey for evaluating the trend of hospital-acquired infections in a university hospital in Turkey
    (Elsevier Sci Ltd, 2011) Ustun, Cemal; Hosoglu, Salih; Geyik, Mehmet Faruk; Parlak, Zafer; Ayaz, Celal
    Objective: To evaluate the validity of a weekly point-prevalence survey (WPS) by comparing it with a prospective-active incidence survey (PIS). Methods: WPS and PIS were conducted at a tertiary referral hospital between January and December 2006. Each Wednesday, an infection control team reviewed all clinical records of patients with hospital-acquired infections (HAIs) by WPS. Routine PIS was conducted with daily visits by the same team. The Rhame and Sudderth formula was used for converting the data between WPS and PIS. Results: During the study period, 1287 HAIs were detected in 37 466 patients by WPS. The mean observed prevalence and calculated prevalence were 5.42% and 5.45%, respectively. The reanimation intensive care unit (ICU) (49.4%) and burns unit (27.6%) had the highest prevalence rates. Pneumonia (0.94%) and urinary tract infections (0.37%) were the most frequent infections. Overall 602 HAIs were detected in 545 patients by PIS. The mean observed incidence and calculated incidence were 2.42/1000-admissions and 2.41/1000-admissions, respectively. The Critical care ICU (37.0/1000-admissions) and burns unit (24.8/1000-admissions) had the highest incidences of HAI. Pneumonia (0.64/1000-admissions) and urinary tract infections (0.37/1000-admissions) were the most frequent infections. Conclusions: This study confirms a close relationship between prevalence and incidence data. WPS may be a useful method for following HAIs when PIS cannot be performed. (C) 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
  • [ X ]
    Öğe
    Critical evaluation of antimicrobial use - A Turkish university hospital example
    (J Infection Developing Countries, 2013) Hosoglu, Salih; Parlak, Zafer; Geyik, Mehmet Faruk; Palanci, Yilmaz
    Introduction: Antimicrobials are being used unnecessarily for different reasons. The aims of this study were: assessment of the quality of antimicrobial use and determination of the factors related to correct use. Method: Antimicrobial practice at Dicle University Hospital (DUH) was evaluated with a point prevalence approach. Using a standardized data collection form, the patients' data (clinic, epidemiology, laboratory and antimicrobial use) was collected. Possible influential factors on antimicrobial use were examined. Results: In the surveillance study 1,350 inpatients were evaluated; 461 (34.1%) of them were using antimicrobials for treatment and 187 (13.9%) for prophylaxis. Antimicrobial indication was found in 355 of 461 patients (77.0%), and the number of antimicrobials was 1.8 per patient in the treatment group. The most common reason for antimicrobial use was community-acquired infection (57.9%). Pneumonia (20.4%), skin and soft tissue infections (9.11%) and urinary tract infections (7.9%) were the most common infectious diseases. Positive culture results were available for 39 patients (8.5.0%) when antimicrobial treatment started. All steps of antimicrobial use were found appropriate in 243 patients (52.7%). In multivariate analyses, clinical manifestation of infection at the beginning (p<0.001), presence of leukocyte counting (p<0.001) and prescription by an infectious disease specialist were found significantly positive factors for wholly appropriate antimicrobial use. Hospitalization with a diagnosis other than infection was found a significantly negative factor for appropriate antimicrobial use (p=0.001). Conclusion: The quality of antimicrobial use could be improved with better clinical and laboratory diagnosis and consultation with infectious diseases specialists
  • Küçük Resim
    Öğe
    Dicle Üniversitesi Hastanesi’nde yatan hastalarda antibiyotik kullanımının değerlendirilmesi
    (2017) Parlak, Zafer; Hoşoğlu, Salih
    [Özet Yok]
  • Küçük Resim
    Öğe
    İmipenem ilişkili konvülziyon: Olgu sunumu
    (Antibiyotik ve Kemoterapi Derneği, 2007) Üstün, Cemal; Geyik, Mehmet Faruk; Avcı, Alper; Parlak, Zafer; Ayaz, Celal
    Beta-laktam grubu antibiyotiklerinin nadir görülen yan etkilerinden biri de konvülziyondur. Acil servise yüksek atefl, öksürük ve solunum s›k›nt›s›yla gelen dokuz yafl›nda erkek hasta ampiyem tan›s›yla yat›r›lm›fl, ampiyem materyalinden yap›lan kültürde GSBL positif Pseudomonas aeruginosa üremifltir. Tedavide imipenem/silastatin ile birlikte amikasin verilmifltir. Klinik ve laboratuvar olarak düzelen hastada tedavinin 18. gününde tonik-klonik kas›lmalarla seyreden konvülziyon geliflmifl, konvülziyonlar imipenem/silastatin tedavisine ba¤lanm›fl ve antibiyoterapi kesilmifltir. Antiepileptik tedavi bafllanan hastada yap›lan incelemelerde konvülziyonu aç›klayacak baflka bir patoloji bulunamam›flt›r. Hasta yat›fl›n›n 21. gününde flifa ile tabucu edilmifltir.