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    Castleman's disease (giant lymph node hyperplasia) of the neck
    (Springer, 2001) Osma, Ü; Cureoglu, S; Yaldiz, M; Topcu, I
    Castleman's disease (giant lymph node hyperplasia) is an uncommon cause of neck mass. Its cause and pathogenesis ale still unknown. Giant lymph node hyperplasia (GLH) usually presents as all asymptomatic solitary mass and can occur anywhere in the head and neck. Diagnostic test results are always inconclusive. Excision and histopathological evaluation are the only ways to make a definitive diagnosis. The disease is curable by surgical excision. A case of GLH presenting as a solitary neck mass in a 68-year-old man is reported. There has been no recurrence during about 7 months.
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    Congenital cholesteatoma of the mastoid region
    (Headley Brothers Ltd, 2000) Cüreoglu, S; Osma, Ü; Oktay, MF; Nazaroglu, H; Meric, F; Topçu, I
    Congenital cholesteatoma may arise in the petrous apex, mastoid, middle ear, or external auditory canal. The least common site being the mastoid process. We present one case of primary mastoid cholesteatoma confirmed by clinical examination, surgical findings and radiological evaluation.
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    The effect of benzalkonium chloride on rabbit nasal mucosa in vivo
    (Springer-Verlag, 2002) Cüreoglu, S; Akkus, M; Osma, Ü; Yaldiz, M; Oktay, F; Can, B; Güven, C
    In this study we investigated the histopathological changes of nasal mucosa after the use of topical benzalkonium-chloride solution. In the study, 28 male New Zealand white rabbits were used. The animals were divided into two groups. In the first group, 50 mul of 0.001% benzalkonium-chloride solution was sprayed into the right nostril and 50 mul of 0.9% saline into the left twice daily for 14 days. In the second group, the same solutions were applied twice daily for 28 days. All of the biopsies from each nasal cavity were processed for electron microscopy. In the nostrils treated with 0.001% benzalkonium chloride, there were areas with obvious squamous cell metaplasia. Some cells showed broken cristae of the mitochondria. Degenerative changes in the supportive and olfactory cells, deformation of nuclei and the increase of heterochromatin were observed. The present investigation has shown that the application of topical benzalkonium chloride does induce degenerative morphologic changes in the nasal mucosa in rabbits in vivo.
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    Normal configuration of the anterior commissure of the glottis on magnetic resonance imaging
    (Springer Verlag, 2000) Cüreoglu, S; Osma, Ü; Ozates, M
    The purpose of this study was to evaluate the normal width of the anterior commissure of the glottis by measuring its dimensions in patients who had no laryngeal disease on magnetic resonance imaging (MRI), but had unrelated cervical pathology. In all, 27 patients were studied. Axial images through the arytenoid commissure at the level of the vocalis muscle and/or vocal process of the arytenoid cartilage were magnified on MRI. The anteroposterior width of the anterior commissure was measured by using an electronic ruler having 1-mm marks. The average width of the anterior commissure was 1.59 +/- 0.6 mm, varying from a minimum width of 1 mm to a maximum width of 3 mm. The width was less than or equal to 2 mm in 25 patients (92.5%). Our results showed that all of the patients studied had measurable mucosal thicknesses at the level of anterior commissure greater than or equal to 1.0 mm.
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    The results of septal button insertion in the management of nasal septal perforation
    (Headley Brothers Ltd, 1999) Osma, Ü; Cüreoglu, S; Akbulut, N; Meric, F; Topcu, I
    Nasal septal perforation may present with various symptoms. Perforations may be surgically closed or managed by obturation, inserting a prosthesis. We used a silicon septal button in the management of nasal septal perforation. In the follow-up period, although the insertion of the nasal septal button alleviated epistaxis, whistling during inspiration, and nasal obstruction, it could not control the production of crusting around the margin of the button.