Yazar "Ketani S." seçeneğine göre listele

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    The effects of exogenous epidermal growth factor on the sialoadenectomized rat liver
    (2009) Ketani S.
    The aim of the present study was to determine endogenous Epidermal Growth Factor (EGF) deficiency with sialoadenectomy and exogenous EGF administration effects on electron microscopic changes in a rat liver. After 27 days sialoadenectomy, transmission electron microscope evaluation indicated that the liver of sialoadenectomy plus exogenous EGF administration group had similar ultrastructural appearance as the control group. This study indicated that short term exogenous EGF supplementation in sialoadenectomized rats can relatively improve liver ultra structure.
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    Effects of propofol on expression ICAM-1 in rabbit gastric endothelial cells
    (2011) Ketani S.; Kanay B.E.; Sagsoz H.
    It was examined the dose-dependent effects of propofol on expression intracellular adhesion molecule (ICAM-1) in rabbit gastric endothelial cells. Twenty adult New Zeland albino rabbits were used in this study. One control and three experimantal groups designed. In experimantal groups 0.5, 4.0, 8.0 mg/kg propofol were applied to rabbits by marginal ear vein. One hour after applying propofol, control and experimantal group rabbits were sacrificed and their gaster were removed. The sections were stained with APAAP immunohistochemical staining for evaluation using a light microscope. No inflammatoric reactions were seen in sections of gastric endothelial cells of control and experimental groups.
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    Radio-protective effects of melatonin on the skin histology in the rat
    (University of Dicle, 2014) Cakir Z.U.; Demirel C.; Ugurlu P.; Saruhan B.G.; Ketani S.; Seker U.; Zincircioglu S.B.
    In this study, the protective effect of melatonin on the radiation-damaged skin was investigated and effectiveness of the protective effect of melatonin was compared with amifostine. Fort this purpose, 40 female Sparague Dawley rats were used. Animals were divided into 5 groups. Control group (C), radiation group (R), and 2 experimental groups (radiation + melatonin 25 mg/kg (R+M) and radiation + amifostin 200 mg/kg (R+WR). A single dose of 20 gy gamma radiation were exposed to the left legs of the rat groups of R, R+M,and R+WR. At the end of a four-week of experiment period, the skin on the left femur of each rat was dissected and routine histological procedures were applied. Nikon Eclipse 400 research microscopy was used for histological observations. All histological structures of the skin were found to be normal in the control group. However, we observed that reduction in thickness of the epidermis and the dermal papillae have disappeared, sweat glands, sebaceous glands and hair follicles atrophy was observed in radiation groups. Our findings showed that R+M group, the thickness of the epidermis, collagen synthesis, R and R+WR group was better with histological structure. As a result, the histological abnormalities of radiation is shaped to protect in the skin, it has been found that melatonin has a significant effect compared to Amifostine (WR2721).