Yazar "Ketani, MA" seçeneğine göre listele

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    The effect of chronic microwave irradiation on the rat sperm count and morphology
    (Pergamon-Elsevier Science Ltd, 1996) Akdag, Z; Celik, MS; Ketani, MA; Deniz, M; Dasdag, S
    [Abstract Not Available]
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    The effect of dexamethasone on gastric mucosal changes following sialoadenectomy in rat
    (Editrice Kurtis S R L, 2005) Elitok, B; Elitok, ÖM; Ketani, MA; Kurt, D; Kanay, Z
    In this study, dexamethasone-induced gastric lesions were studied in rats that had undergone sialoadenectomy. The ultrastructural changes developed during the study were detected by electron microscopically, while blood serum and stomach epidermal growth factor (EGF) concentrations were measured by RIA. The result of the study showed that gastric lesions were correlated with gastric mucus secretion and both serum and mucosa EGF levels. After the administration of dexamethasone, it was found that sialoadenectomy significantly (p < 0.01) raised the incidence of stomach lesions (p < 0.01), and a significant increase in mucus secretion was also found. Additionally, the serum and gastric mucosal EGF levels fell after sialoadenectomy when compared to normal rats. The most important gastric mucosal changes were observed in rats treated with dexamethasone and those both sialoadenectomised and treated with clexamethasone.
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    The effect of microwave on experimental orthodontic tooth movement
    (Pergamon-Elsevier Science Ltd, 1996) Karadede, I; Ketani, MA; Akdag, Z; Celik, S; Dasdag, S
    [Abstract Not Available]
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    The effect of microwave radiation on morphology of rat epididymidis
    (Pergamon-Elsevier Science Ltd, 1996) Akdag, Z; Celik, S; Nergiz, Y; Ketani, MA; Dasdag, S
    [Abstract Not Available]
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    The effect of microwave radiation on morphology of rat testis
    (Pergamon-Elsevier Science Ltd, 1996) Nergiz, Y; Akdag, Z; Celik, S; Ketani, MA; Dasdag, S
    [Abstract Not Available]
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    The effects of epidermal growth factor deficiency on ultrastructure of tongue epithelium of rat
    (Indian Veterinary Journal, 2006) Kilinc, M; Ketani, S; Zengingul, AI; Dag, A; Ketani, MA
    [Abstract Not Available]
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    Effects of tamoxifen administration in rat vaginas
    (I R O G Canada, Inc, 2002) Ketani, MA; Ketani, S; Kaloglu, C; Güney, B
    Background: Tamoxifen (TAM) inhibits the initiation of carcinogen induced rat mammary tumours and is administrered for extended periods after the initiation of carcinogenesis. It is also a widely used treatment for breast and gynaecological cancer. Objective: In this study, we aimed to investigate tamoxifen (TAM) administration on vagen development in rats. Material & Methods: Twenty sexually mature and pregnant Wistar albino rats were chosen as the animal model. They were divided into two groups. Group 1: Control group, Group II: Tamoxifen applied (between gestational day 16 and 21 days); 100 mug tamoxifen citrate (TAM) in 0.05 ml saline subcutaneously per day/animal. After birth, all female rats were sacrificed on the 60(th) day and were taken vaginal tissue. Transmission electron microscopy and light microscopy have been used to study changes to the vaginal epithelium. Results: A statistically significant reduction of birth body weight was noted in the experimental group of rats when compared to the control group (P<0.05). We saw increase in the thickness of the epithelium layer and irregularity and disappearance of microscopic papilla, cytoplasmic vacuolation in cells of the surface layer, thin and irregular basal membrane, lateral junction of cells were destroyed in the TAM treated groups. In conclusion, neonatal tamoxifen administration affects vagina epithelium and lead to decreasing birth,body weight and vaginal adenosis.
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    Intravesical oxybutynin application: Ultrastructural effects on bladder epithelium.
    (Mbr Press Inc, 1999) Ersay, A; Ketani, MA; Nergiz, Y; Demirtas, OC; Akkus, M; Otludil, B
    Intravesically applied oxybutynin, rapidly absorbs into the bloodstream, additional to profound local effect. Currently morphologic effects of oxybutynin on local bladder tissue relatively well established at light microscopic level, but not ultrastructural level. Thirty New Zealand White female rabbits were catheterized daily and intravesical instillation were performed with whether 1mg/kg oxybutynin solution or saline for 30 days. The local effects of the drug on bladder epithelium at electron microscopic level were examined comparing with saline administration. Urinary tract infection (UTI) incidence were similar in both saline and oxybutynin groups (9 vs. 10 of 15 animals respectively) (p>0.05). Interestingly, in 4 of 5 animals that received oxybutynin and never had UTI during the study, separation of zonula occludens intercellular junction was determinated by Jeol electron microscope. This observation can explain rapid absorption of oxybutynin through the bladder into the blood stream. Oxybutynin can damage bladder surface epithelium at ultrastructural level. This effect may lead to increase absorption of it, but not result in higher incidence of bacterial infection.
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    The investigation of the effect of microwave on rat TMJ
    (Pergamon-Elsevier Science Ltd, 1996) Karadede, I; Akdag, Z; Ketani, MA; Dasdag, S; Celik, S
    [Abstract Not Available]
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    The protective effect of sinusoidal electromagnetic field on the osteoporotic tibia of rat
    (Indian Veterinary Journal, 2003) Ketani, MA; Buyukbayram, H; Gur, A; Sert, C; Gunduz, S
    [Abstract Not Available]
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    The role of enzymatic antioxidant defense system and lipid peroxidation on gentamicin nephrotoxicity in rat renal tissues
    (Mbr Press Inc, 1998) Isik, FB; Erdinc, L; Mete, N; Erdinc, M; Ketani, MA; Yokus, B
    The activities of antioxidant enzymes, superoxide dismutase (SOD), Glutathione peroxidase (GSH-Px) and catalase (CAT), and the levels of malondialdehyde (MDA), an end product of lipid peroxidation, in kidney tissues were measured in rats treated with gentamicin alone (100 mg/kg/day subcutaneously (s.c.)) for 10 days or gentamicin together with vitamin E (300 mg/kg/day intraperitoneally (i.p)) for 10 days. Gentamicin caused depression in activities of the antioxidant enzymes (SOD, GSH-Px, CAT)) and elevation in MDA levels. These effects were highly significant when compared to the effects of placebo in control group (P < 0.001). Vitamin E was found to be ineffective for preventing gentamicin induced nephrotoxicity as determined both functionally and histopathologically. Although there was a borderline decrease of MDA levels (p < 0.05) in rats taking vitamin E, there was no difference in the activities of antioxidant enzymes between the rats taking gentamicin with or without vitamin E. Our finding suggests that gentamicin nephrotoxicity causes a decrease in the activities of antioxidant enzymes and an increase in the level of lipid peroxidation, and vitamin E do not has any preventive effect against gentamicin nephrotoxicity.
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    Whole-body microwave exposure emitted by cellular phones and testicular function of rats
    (Springer, 1999) Dasdag, S; Ketani, MA; Akdag, Z; Ersay, AR; Sari, I; Demirtas, ÖC; Celik, MS
    This study investigated whether there are adverse effects due to microwave exposure emitted by cellular phones in male rats. Eighteen Wistar Albino rats were separated into three groups, a sham group and two experimental groups. The rats were confined in Plexiglas cages and cellular phones were placed 0.5 cm under the cages. In the first experimental group, cellular phones were in standby position for 2 h. In the second experimental group. phones were turned to the speech position three times each for 1 min duration over 2 h. Rats in the first and second experimental groups were exposed to microwaves emitted by phones for 2 h/day for a duration of 1 month. After the last exposure the rats were killed. Brain, eyes, ears, liver, heart, lungs, stomach, kidneys, testes. small and large intestines and skill of the rats were observed histologically. The decrease of epididymal sperm counts in the speech groups were not found to be significant (P > 0.05). Differences in terms of normal and abnormal sperm forms were not observed (P > 0.05). Histological changes ut ru especially observed in the testes of rats of the speech groups. Seminiferous tubular diameter of rat testes in the standby and speech groups was found to be lower than the sham group (P < 0.05). Rectal temperatures of rats in the speech group were found to be higher than the sham and standby groups (P < 0.05). The rectal temperatures of rats before and after exposure were also found to be significantly higher in the speech group (P < 0.05). Specific absorption rate (SAR) was determined as 0.141 W/kg.