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    Dosimetric comparison of prostate radiotherapy between pelvic node-positive and node-negative patients
    (IJRR-Iranian Journal Radiation Research, 2021) Zincircioğlu, Seyit Burhanedtin; Doğan, M. H.; Kaya, M. A.; Teke, Fatma;
    Background: The importance of dose in prostate radiotherapy is well known, and the dosimetric effects of radiotherapy in node-positive or node-negative patients with prostate cancer have become an important issue. Materials and Methods: Helical tomotherapy (TH) plans of 19 pelvic node-positive [THpn(+) plan] or node-negative [THpn(-) plan] patients with prostate cancer were retrospectively created in our clinic. In these plans, the beam angle was set to cover the planning target volume (PTV) of prostate cancer and minimize the dose to the organs at risk, including the bladder, rectum, femoral head, and bowel. Results: There were no differences in the conformity index, D-max, D-mean, and homogeneity index of PTV between the THpn (+) and THpn (-) plans (p>0.05). However, V95 in the THpn (+) plan was lower than that in the THpn (-) plan (p=0.017). Moreover, D-max, V75, V70, V65, V60, V50, V40, V30, and V20 for the rectum were not significantly different between the two plans (p>0.05), whereas D-mean was significantly different (p=0.025). D-max, V70, V65, and V60 for the bladder were not significantly different between the two plans (p>0.05), whereas V55, V50, V40, and V30 were significantly different (p<0.05). Finally, D-max and V50 for the femoral head and bowel were significantly different between the two plans (p<0.05). Conclusion: The THpn (+)] and [THpn(-) plans achieved acceptable target dose coverage in prostate radiotherapy.
  • [ X ]
    Öğe
    Dosimetric comparison of TomoDirect and TomoHelical plans in post-mastectomy chest wall radiation therapy
    (Ijrr-Iranian Journal Radiation Res, 2017) Teke, F.; Dogan, M. H.; Kaya, M. A.; Gumus, M.
    Background: The purpose of this study was to evaluate the characteristics of TomoDirect (TD) plans compared to conventional TomoHelical (TH) plans in chest wall irradiation in patients with breast cancer. Materials and Methods: TD and TH plans for only chest wall were retrospectively created for 30 patients previously treated with TH technique in our clinic. The beam angles were arranged to cover PTV chest wall and to minimize doses to OARs, ipsilateral lung and contralateral breast in TD plan. The prescribed dose was 50 Gy in 25 fractions. Results: The mean treatment times were similar in TH and TD (310.8 and 309 s, respectively, p>0.05). There was no difference between the values of CI and HI of both plans (p>0.05). The values of Dmean, V5 and V20 of the ipsilateral lung in TD plan was significantly lower than that in TH plan for all 30 patients (p<0.001, p<0.001 and p=0.001, respectively). V25 and V30 values of the heart were significantly lower in TH than those in TD plan in left-sided chest wall irradiation (p=0.006 and p<0.001, respectively). However, V5 values in TH was significantly higher than those in TD (p<0.001). In the right-sided, there was no difference between two plans for V25 and V30 values of heart (p>0.05). Conclusion: Both of TH and TD plans produce acceptable target dose coverage in chest wall RT. Considering the risk of low-dose radiation to the critical organs; TD mode improve dose distribution.