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    Öğe
    Cardiac device-related infective endocarditis; analysis of 15 cases
    (Turkish Soc Cardiology, 2013) Elbey, Mehmet Ali; Eren, Nihan Kahya; Kalkan, Mehmet Emin; Demirtas, Sinan; Kahraman, Fatih; Sayin, Rasit; Oylumlu, Mustafa
    Objectives: We aimed to investigate the demographic and clinical characteristics, echocardiographic and microbiologic features, and outcomes of patients with permanent pacemaker (PM), and implantable cardioverter-defibrillator (ICD) - related endocarditis in this study. Study design: The study population consisted of 15 patients with permanent PM and ICD-related endocarditis. Data on patients'demographic characteristics, medications used, clinical, and microbiological data, echocardiographic findings, types, and outcomes of surgical treatments were recorded. Results: The mean age of the patients was 57+/-16. Seven patients (47%) were female. Of the 15 patients with permanent PM and ICD-related endocarditis, 5 died during in-hospital follow-up (33%). In four patients (27%) pulmonary embolism developed. Culture-negative endocarditis was detected in 5 cases (33%). Staphylococci were the most common causative organisms in 60% of the patients. Three (20%). patients underwent surgical treatment Conclusion: Cardiac device-related endocarditis remains a rare complication of intracardiac device implantation still with higher mortality rates.
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    Öğe
    Kardiyak cihazlara bağlı olarak gelişen enfektif endokardit; 15 olgunun analizi
    (2013) Eren, Nihan Kahya; Demirtaş, Sinan; Elbey, Mehmet Ali; Oylumlu, Mustafa; Kalkan, Mehmet Emin; Sayın, Muhammet Raşit; Kayan, Fethullah
    Amaç: Bu çalışmada, kalıcı pacemaker (PM) ve implante edilebilir kardiyoversiyon defibrilatörleri (ICD) ile ilişkili endokarditin demografik, klinik ekokardiyografik ve mikrobiyolojik özellikleri ve sonuçlarının araştırılması amaçlandı.Çalışma planı: Kalıcı PM ve ICD endokarditi tanısı olan 15 hasta çalışmaya alındı. Hastaların demografik özelikleri, kullandıkları ilaçlar, klinik ve mikrobiyolojik özellikleri, ekokardiyografi sonuçları, cerrahi tedavi ve sonuçları kaydedildi.Bulgular: Hastaların ortalama yaşı 57±16 ve 7si (%47) kadındı. Kalıcı PM ve ICDsi olan 15 hastadan 5i takip sırasında kaybedildi (%33). Dört hastada pulmoner emboli gelişti (%27). Kan kültürü 5 hastada (%33) negatif bulundu. Hastaların %60ında üretilen stafilokoklar en sık saptanan mikrobiyolojik ajanlardı. Üç hastaya (%20) cerrahi tedavi uygulandı.Sonuç: Kardiyak cihazlarla ile ilişkili endokardit, kardiyak cihaz implantasyonun nadir bir komplikasyonu olmasına rağmen mortalitesi halen yüksek olan bir hastalıktır.
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    Öğe
    A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis
    (Turkish Soc Cardiology, 2013) Elbey, Mehmet Ali; Akdag, Serkan; Kalkan, Mehmet Emin; Kaya, Mehmet G.; Sayin, M. Rasit; Karapinar, Hekim; Bulur, Serkan
    Objective: The aim of this retrospective multicenter study was to investigate the clinical manifestations, microbiological profile, echocardiographic findings and management strategies of infective endocarditis (IE) in Turkey. Methods: The study population consisted of 248 Turkish patients with IE treated at 13 major hospitals in Turkey from 2005 to 2012 retrospectively. All hospitals are tertiary referral centers, which receive patients from surrounding hospitals. Data were collected from the medical files of all patients hospitalized with IE diagnosed according to modified Duke Criteria. Results: One hundred thirty seven of the patients were males. Native valves were involved in 158 patients while in 75 participants there was prosthetic valve endocarditis. Vegetations were detected in 223 patients (89%) and 52 patients had multiple vegetations. Mitral valve was the most common site of vegetation (43%). The most common valvular pathology was mitral regurgitation. The most common predisposing factor was rheumatic valvular disease (28%). Positive culture rate was 65%. Staphylococci were the most frequent causative microorganisms isolated (29%) followed by enterococci (11%). In-hospital mortality rate was 33%. Conclusions: Compared to IE in developed countries younger age, higher prevalence of rheumatic heart disease, more frequent enterococci infection and higher rates of culture negativity were other important aspects of IE epidemiology in Turkey.
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    Öğe
    Predictors of mortality in patients with prosthetic valve infective endocarditis: A nation-wide multicenter study
    (Via Medica, 2013) Elbey, Mehmet Ali; Kalkan, Mehmet Emin; Akdag, Serkan; Ozbek, Kerem; Eren, Nihan Kahya; Demirtas, Sinan; Akil, Mehmet Ata
    Background: Our aim was to investigate the clinical and prognostic features of the patients with prosthetic valve endocarditis (PVE) in a multicenter nation-wide study. Methods: The present nation-wide study consisted of 75 consecutive patients with PVE treated at 13 major hospitals in Turkey from 2005 to 2012. Results: The patients who died during follow-up were significantly older than the survivors and had higher C-reactive protein (CRP), creatinine, poor NYHA functional class and large vegetations. High creatinine level (odds ratio [OR] 2.6, 95% confidence interval [CI] 1.14-6.13), poor functional status (OR 24.5; 95% CI 3.1-196.5) and high CRP (OR 1.02; 95% CI 1.00-1.03) measured on admission were independent risk associates for in-hospital mortality Conclusions: High creatinine level, poor functional status and high CRP measured on admission were independent risk associates for in-hospital mortality, whereas a NYHA class of III/IV and high CRP reflected independent risk for stroke/mortality end point.