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    Extrahepatic abdominal hydatid disease caused by Echinococcus granulosus
    (Amer Roentgen Ray Soc, 2007) Ilica, Ahmet Turan; Kocaoglu, Murat; Zeybek, Nazif; Guven, Suleyman; Adaletli, Ibrahim; Basgul, Alin; Coban, Hidayet
    OBJECTIVE. The classical findings in hydatid disease caused by Echinococcus granulosus with liver or lung involvement are well known. However, diagnosing hydatid disease at unusual locations may be challenging because of variable imaging appearances depending on the host reaction. The purpose of this pictorial essay is to review the sonographic, CT, and MRI features of extrahepatic abdominal hydatid disease including intraperitoneum, retroperitoneum, diaphragma, bone, and soft tissue of the abdomen. CONCLUSION. Extrahepatic abdominal hydatid lesions have nearly identical imaging features, including the presence of cyst wall calcification, daughter cysts, and membrane detachment. The combinations of radiologic and serologic tests especially in patients living in the endemic areas contribute to the diagnosis. Despite their rarity, being familiar with the spectrum of radiologic findings in these unusual sites is helpful to improve diagnostic accuracy.
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    Serum IL-6 Level May Have Role in the Pathophysiology of Unexplained Infertility
    (Wiley-Blackwell Publishing, Inc, 2009) Demir, Bulent; Guven, Suleyman; Guven, Emine Seda Guvendag; Atamer, Yildiz; Gul, Talip
    Problem The aim of this study was to compare the serum levels of interleukin (IL)-6 of women with unexplained infertility with fertile subjects. Method of study Serum IL-6, and tumor necrosis factor-alpha (TNF-alpha) levels of 45 infertile and 44 fertile women on day 3 of menstrual cycle were assessed and compared for this prospective controlled study. Results The mean serum IL-6 level was significantly higher in women with unexplained infertility, compared with fertile women (5.71 +/- 1.81 and 4.31 +/- 1.79, P < 0.001, Student's t-test). There was no significant difference in TNF-alpha level among the groups. Conclusion Significant difference in serum IL-6 levels between unexplained infertile and fertile women suggests that this cytokine may be involved in pathophysiology of unexplained infertility.
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    Serum leptin level in women with unexplained infertility
    (Elsevier Ireland Ltd, 2007) Demir, Bulent; Guven, Suleyman; Guven, Emie Seda Guvendag; Atamer, Yildiz; Gunalp, G. Serdar; Gul, Talip
    Introduction: The aim of this study was to compare serum levels of leptin in women with unexplained infertility with fertile subjects. Material and method: Serum leptin levels of 27 infertile and 30 fertile women on day 3 of the menstrual cycle were assessed and compared in this prospective age and body mass index (BMI) comparable controlled study. Results: The mean age in the infertile group was 29.3 (range, 23-38), while this figure was 28.9 (range, 19-39) in the fertile group; the mean BMIs were 24.5 (range, 20.6-27.8) and 25.0 (range, 21.8-28.7), respectively. The mean serum leptin level was significantly higher in women with unexplained infertility compared with fertile subjects. Considering normal weight subjects, mean serum leptin levels were increased significantly in the unexplained infertile group compared with the fertile group (7.2 (range, 4.3-10.4) versus 3.5 (range, 1.9-6.2) ng/ml, respectively;p < 0.0001, Mann-Whitney U-test). The significant increase in serum leptin levels was observed also in overweight patients (6.8 (range, 1.3-5.2) versus 3.3 (range, 4.2-8.9) ng/ml, respectively; p < 0.0001, Mann-Whitney U-test). Conclusion: A significant difference in serum leptin levels between unexplained infertile and fertile women suggests that this cytokine may be involved in pathophysiology of unexplained infertility. (c) 2007 Elsevier Ireland Ltd. All rights reserved.