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    Attitudes and perceptions of pharmacy students toward pharmacognosy and related competencies of the national core education program in Türkiye
    (İstanbul Üniversitesi, 2023) Şahin, Hasan; Gökkaya, İçim; Yazıcı, Nurdan
    Background and Aims: Competency-based education (CBE) and the use of natural health products have been increasingly discussed in pharmacy. The national core education program of Türkiye has 108 mandatory competencies. This study investigated pharmacy students’ thoughts about pharmacognosy and their preparedness to provide related competencies. Methods: A descriptive online survey consisting of a 35-item questionnaire was administered to pharmacy students in Türkiye between June and July 2023. A 3-point Likert scale was used to assess students’ opinions. Data were analyzed using SPSS 23.0 (P < 0.05). Results: A total of 404 students in the third, fourth, and fifth years from 19 different faculties participated in the study. The interest in pharmacognosy was high, and students attributed significant value and importance to the field. Most of the students believed that their pharmacognosy education (67.1%) is sufficient, particularly on herbal medicinal plants (62.4%) and traditional and complementary medicine (59.2%). However, their satisfaction rates with education on marine pharmacognosy (10.4%) and drugs sourced from animals (30.2%) and microorganisms and minerals (32.2%) were low. Students rated their preparedness toward related competencies at concerning levels. The lowest value was observed in homeopathy (21.0%). Students felt more confident in academic and industrial practices (52.4%) than in community and hospital pharmacy requirements (35.3%). The impacts of national accreditation status and the education model of the faculties were found to be limited. Conclusion: An overall review may be needed to adapt the field to outcome-based education or CBE.
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    Evaluation of Hedera species as herbal medicine raw materials
    (Taylor and Francis Ltd., 2024) Gökkaya, İçim; Yazıcı, Nurdan; Seyhan, Gökçe; Çakır, Oğuz; Yılmaz, Mustafa Abdullah; Barut, Burak; Renda, Gülin
    This study aimed to evaluate the potential of Hedera colchica as an alternative to Hedera helix species for the treatment of mild inflammatory conditions of the upper respiratory tract and chronic inflammatory bronchial diseases. The H. colchica extract with the highest saponin content (C3S; 468.19 ± 16.01 mg HE/g dry weight) and the extract with the highest total phenol content (C1F; 108.60 ± 5.61 mg GAE/g dry weight). Chemical analysis and standardisation of the extract with the highest selective COX-2 inhibitory effect was performed using the LC-MS/MS technique. It was determined that the substances found in the highest ratio in the C1F extract were quinic acid (45.909 µg/g extract) and hesperidin (37.077 µg/g extract). As a result, secondary metabolites, in addition to saponins, found in Hedera species may also contribute to the extract’s effectiveness, more potent extracts can be obtained compared to the total extract-containing preparations available in the market.