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  • Küçük Resim
    Öğe
    Clinical and laboratory characteristics of children with Kawasaki disease
    (Dicle Üniversitesi, 2015) Akın, Fatih; Emiroğlu, Melike; Sert, Ahmet; Arslan, Şükrü; Solak, Ece Selma
    Objective: In this study, we aimed to evaluate clinical and laboratory characteristics of patients with Kawasaki disease (KD) in Konya region of Turkey. Methods: The hospital records of patients who were hospitalized with the diagnosis of KD in the Pediatrics Clinics of Konya Training and Research Hospital between May 2010 and June 2012 were reviewed retrospectively. Results: Seven cases were found to have the diagnosis of KD, two of whom were incomplete KD. Oropharynx changes were the most common (100%) feature in our patients. Five (71%) patients had bulbar conjunctivitis. Three (43%) patients had erythema at the site of BCG inoculation. Adenopathy was present in all of our patients with the classical form. A desquamation was observed in one case at the seventh day of fever. No cardiac manifestation was seen. Elevated erythrocyte sedimentation rate and thrombocytosis were present in all patients. All of the patients were received intravenous immunoglobulin in the first ten days of the fever. Conclusion: KD should be considered as a possible diagnosis in any child presenting with prolonged fever. BCG reaction can be attributed as a diagnostic criterion for incomplete form of the disease especially in countries where BCG vaccination is routinely performed. Early treatment is essential to prevent cardiovascular complications.
  • Küçük Resim
    Öğe
    Serotype distribution of Streptococcus pneumoniain children with invasive disease in Turkey: 2015-2018
    (Taylor & Francis, 2020) Ceyhan, Mehmet; Aykaç, Kübra; Gürler, Nezahat; Özsürekçi, Yasemin; Öksüz, Lütfiye; Akisoğlu, Özlem Altay; Öz, Fatma Nur; Emiroğlu, Melike; TürkDağı, Hatice; Yaman, Akgün; Söyletir, Güner; Öztürk, Candan; Akpolat, Nezahat; Özakın, Cüneyt; Aydın, Faruk; Aydemir, Şöhret; Kiremitçi, Abdurrahman; Gültekin, Meral; Camcıoğlu, Yıldız; Zer, Yasemin; Güdücüoğlu, Hüseyin; Gülay, Zeynep; Birinci, Asuman; Arabacı, Çiğdem; Karbuz, Adem; Devrim, İlker; Sorguç, Yelda; Baysan, Betil Özhak; Öncel, Eda Karadağ; Yılmaz, Nisel; Altıntop, Yasemin Ay
    Objectives: To determine the serotype distribution of pneumococcus causing invasive pneumococcal disease (meningitidis, bacteremia and empyema) in children in Turkey, and to observe potential changes in this distribution in time to guide effective vaccine strategies. Methods: We surveyed S. pneumoniae with conventional bacteriological techniques and with real-time polymerase chain reaction (RT-PCR) in samples of cerebrospinal fluid (CSF), blood and pleural fluid. S. pneumoniae strains were isolated from 33 different hospitals in Turkey, which are giving health services to approximately 60% of the Turkish population. Results: A total of 167 cases were diagnosed with invasive pneumococcal disease between 2015 and 2018. We diagnosed 52 (31.1%) patients with meningitis, 104 (62.2%) patients with bacteremia, and 11 (6.6%) patients with empyema. Thirty-three percent of them were less than 2 years old and 56% less than 5 years old. Overall PCV13 serotypes accounted for 56.2% (94/167). The most common serotypes were 19 F (11.9%), 1 (10.7%) and 3 (10.1%). Conclusions: Besides the increasing frequency of non-vaccine serotypes, vaccine serotypes continue to be a problem for Turkey despite routine and high-rate vaccination with PCV13 and significant reduction reported for the incidence of IPD in young children. Since new candidate pneumococcal conjugate vaccines with more serotype antigens are being developed, continuing IPD surveillance is a significant source of information for decision-making processes on pneumococcal vaccination.