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    Effect of Ramadan fasting on platelet aggregation in healthy male subjects
    (Springer, 1996) Aybak, M; Turkoglu, A; Sermet, A; Denli, O
    The purpose of this study was to examine platelet aggregation during Ramadan fasting. A group of 20 healthy non-smoking male volunteers were studied, whose mean age was [21 (SD 2.4) years range 19-24]. The average fast was about 15 h. Venous blood samples were taken on 4 different days; 1 day before Ramadan (day 0), then on the 1st, 14th and 28th day of Ramadan, On each of these 4 days, blood samples were taken at 4 p.m. (1 h before the evening meal). Body mass index and platelet count did nor change during fasting. Bleeding and coagulation time had increased significantly by the end of Ramadan fasting (P < 0.05, P < 0.005 respectively), but these changes remained within physiological Limits. Ramadan fasting induced a reduction in platelet sensitivity to adenosine 5'-diphosphate (ADP) and collagen on days 14 (P < 0.05) and 28 (P < 0.05, P < 0.005 respectively). However, adrenaline-induced. platelet aggregation decreased only on day 25 (P < 0.05). This study indicated that Ramadan fasting led to a decrease in the platelet responses of different aggregating agents (ADP, adrenaline and collagen) in vitro. It also led to an increase in bleeding and coagulation time.
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    Öğe
    An investigation of the copper (Cu), zinc (Zn) and selenium (Se) levels of blood serum and the Cu and Zn levels of wool of Akkaraman ewes in the Diyarbakir region
    (Scientific Technical Research Council Turkey, 2001) Kurt, D; Denli, O; Kanay, Z; Güzel, C; Ceylan, K
    The aim of this study is to determine the copper, zinc and selenium levels of blood serum and the Cu and Zn levels of wool of healthy Akkaraman ewes grazed in the meadows in the Diyarbakir region. A total of 60 units of blood and wool samples from various villages in different counties of Diyarbakir (Bismil, Cinar, Ergani, Silvan, Kocakoy and some Diyarbakir villages] were studied. The Cu, Zn and Se levels of sera and the Cu and Zn levels of wool were analyzed by flameless atomic absorption spectrophotometer. We found significant differences in Cu and Se levels of sera, in Cu levels of wool (p<0.01) and in Zn levels of wool (p<0.05 ) in ewes from various counties, whereas no significant differences were observed in Zn levels of sera (p>0.05). Although there were considerable differences from county to county, the average values of these counties and herds that indicated the lowest Values in respect to Cu and Zn contents were found to be either similar to or just over the normal values. However, in the case of the selenium content, the average serum Se level of the Akkaraman ewes from various counties of Diyarbakir, except the central county, was found to be remarkably lower than the normal values. In the light of these findings, the rations of animals grazing in meadows are recommended to be reinforced with Se content.