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Öğe Evaluation Of T Peak-T End Interval In Patients With Chronic Obstructive Pulmonary Disease (COPD)(Amer Thoracic Soc, 2016) Karadeniz, G.; Ucsular, F.; Demir, M.; Kir, S. Bulac; Doruk, S.[Abstract Not Available]Öğe A novel predictor in patients undergoing heart valve surgery: systemic inflammation response index: a single center cross-sectional study(Verduci Publisher, 2023) Karacalilar, M.; Demir, M.OBJECTIVE: Inflammation plays a pivotal role in heart valve disease (HVD). This study aimed at evaluating the prognostic value of systemic inflammation response index (SIRI) after valve replacement surgery.SUBJECTS AND METHODS: The study en-rolled 90 patients who underwent valve replace-ment surgery. SIRI was calculated using labo-ratory data on admission. Receiver operating characteristic (ROC) analysis was used to calcu-late the optimal cutoff values of SIRI for predict-ing mortality. Univariable and multivariable COX analysis was used to assess the relationship of SIRI with clinical outcomes.RESULTS: 5-year mortality rate was high-er in SIRI >= 1.55 group than SIRI <1.55 group [16 (38.1%) vs. 9 (18.8%)]. In receiver operating char-acteristic analysis, the optimal cutoff values for SIRI were 1.55 (area under the curve 0.654, p: 0.025). Univariable analysis revealed that SIRI [OR: 1.41, 95%CI (1.13-1.75), p<0.001] was an in-dependent predictor of 5-years mortality. Multi -variable analysis revealed that glomerular filtra-tion rate (GFR) [OR: 0.98, 95%CI (0.97-0.99)] was an independent predictor of 5-years mortality.CONCLUSIONS: Although SIRI is a preferable parameter for the detection of long-term mortali-ty, it failed to predict in-hospital and 1-year mor-tality. Larger multi-center studies are needed to investigate effect of SIRI on prognosis.Öğe Predictive value of lymphocyte to monocyte ratio for cardiac syndrome X(Verduci Publisher, 2022) Akil, M. A.; Oylumlu, M.; Demir, M.; Ozbek, M.; Polat, N.; Acet, H.; Bilik, M. Z.OBJECTIVE: Cardiac syndrome X (CSX) is typically described with ischemia in stress tests in addition to angina-like chest pain and without stenosis in coronary angiography. We aimed at determining the relationship between LMR and CSX. PATIENTS AND METHODS: We retrospectively collected patients with CSX between January 2016 and December 2019. Patients with typical angina-like chest pain, normal 12-lead electro-cardiography at rest, a positive response to the exercise test (> 0.1 mV ST-segment depression at 80 ms after the J point in two or more contiguous leads) or ischemia on myocardial perfusion scintigraphy and normal coronary angiography were included in the study as CSX patients. RESULTS: This study consisted of 116 patients with CSX and 153 control groups. The mean age of the patients with CSX was 52.7 +/- 9.7 years, and the mean age of the control group was 53.7 +/- 10.6 years (p= 0.416). The patients with CSX were more likely to have higher monocyte counts and LMR. According to the Pearson correlation test, the CRP value negatively correlated with the LMR. In multivariate logistic regression analysis, LMR remained a significant predictor of CSX. In ROC analysis, LMR <4.1 had 64% sensitivity and 50% specificity (ROC area under curve: 0.587, 95% CI: 0.519-0.655, p=0.015) in accurately predicting a CSX diagnosis. CONCLUSIONS: We showed that lower LMR levels were associated with the presence of CSX.Öğe Prognostic importance of nutritional assessment in patients with acute ischemic stroke undergoing endovascular thrombectomy(Verduci Publisher, 2023) Ozbek, M.; Akil, M. A.; Demir, M.; Arik, B.; Demir, F.; Akil, E.- OBJECTIVE: The prevalence of malnutrition in patients with acute isch-emic stroke (AIS) can range from 8% to 34%. It has been shown that prognostic nutritional in-dex (PNI) and control nutritional status (CO -NUT) scores can provide an opportunity to make prognostic predictions in some disease groups. Previous studies have shown a close relationship between malnutrition scores and stroke prognosis. We evaluated the effect of nutritional scores on in-hospital and long-term mortality in AIS patients undergoing endovas-cular therapy (EVT).PATIENTS AND METHODS: 219 patients who underwent EVT for the AIS were included in this retrospective design and cross-sectional study. The primary endpoint of the study was accepted as all-cause death including in-hospital death, 1-year death, and 3-years death. RESULTS: A total of 57 patients died in the hospital. In-hospital mortality rate was higher in the high CONUT group [36 (49.3%), 10 (13.7%), 11 (15.1%), p<0.001]. A total of 78 patients died within one year, and 1-year mortality was higher in the high CONUT group [43 (58.9%), 21 (28.8), 14 (19.2), p<0.001]. At the end of the 3-year fol-low-up, 90 patients had died, and the 3-year mortality rate was significantly higher in groups with a high CONUT score than in those with a low CONUT score (p<0.001).CONCLUSIONS: A higher CONUT score, cal-culated easily by simple scoring with parame-ters studied from peripheral blood before the EVT procedure, is an independent predictor of in-hospital, 1-year, and 3-years all-cause mor-tality.Öğe Serum IL-2R, IL-6, Ig G, Ig G subgroups (IgG 1, 2, 3, 4) levels in iron deficiency anemia and ?-thalassemia carriers(Blackwell Publishing, 2006) Demir, M.; Canoruc, N.; Batun, S.; Kale, E.; Erdinc, L.; Kaplan, A.[Abstract Not Available]Öğe Sevoflurane induced diffuse alveolar haemorrhage in a young patient after orthopedic surgery: A case report(Wolters Kluwer Medknow Publications, 2020) Cengiz, O.; Kivrak, A.; Yegen, M.; Demir, M.We present a very rare case of Sevoflurane Induced Diffuse Alveolar Haemorrhage in a young male patient with a closed tibial fracture after direct trauma to the right cruris. The patient was operated for tibial fracture, but diffuse alveolar haemorrhage developed after sevoflurane inhalation in the postoperative period following general anesthesia. Diffuse alveolar haemorrhage (DAH) is associated with inhalation injury from halogenated gases and reported as a unique entity in the literature that practicing clinicians should be aware of and consider in post-operative cases of acute respiratory distress. As DAH usually presents with symptoms the presence of hemoptysis, anemia, dyspnoea and radiological alveolar infiltrates, rapid detection of the aetiology and initiation of cause-directed treatment are of great importance on survival.