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Öğe Are Primary Health Care Workers Aware of Cervical Cancer Risk?(Asian Pacific Organization Cancer Prevention, 2014) Can, Huseyin; Erdem, Ozgur; Oztekin, Coskun; Celik, Sercan Bulut; Onde, Mete; Celepkolu, Tahsin; Ongel, KurtulusBackground: We here examined the awareness of female health employees (doctors, nurses, midwives) working in primary health care service about cervical cancer and its risk factors. Additionally attitude and behavior for gynecologic examination and pap smear screening wwere researched. Materials and Methods: This cross-sectional, descriptive study con cerned female health employees working at primary health care services in two southern cities of Turkey, over a four month period in 2013. Participants were recently or previously sexually active research was explained and verbal informed consent was obtained face to face. The questionnaire consisted of two parts; socio-demographic characteristics and level of knowledge about cervical cancer and its risk factors. Results: The average age of the participants (midwives 43.7%, n=143; nurses 40.4%, n=132; doctors 6.4%, n=21; emergency medical technicians and others, 9.5%, n=31; total, n=327) was 30.9 +/- 6.41 years. 64.2% (n=210) were working in Diyarbakir and 35.8% (n=117) in Batman. A large proportion reported low knowledge and inadequate screening practice Conclusions: Health employees should be better informed about the importance of screening for cancers, given their preventive roles for the general population.Öğe THE EVALUATION OF NEPHROPATHY RISK FACTORS IN TYPE 2 DIABETES(Carbone Editore, 2014) Celepkolu, Tahsin; Tanriverdi, Mehmet Halis; Celk, Sercan Bulut; Bucaktepe, Pakize Gamze Erten; Can, Huseyin; Aslan, Ilknur; Kibrisli, ErkanIntroduction: The prevalence of diabetes has been increasing at an alarming rate worldwide. Thus, the complications of diabetes are increasingly prevalent and each year three million people die as a result of its chronic complications. In our study, we aimed to compare nephropathic and non neplzropathic patients according to socio-denzographic features, biochemical parameters, and proteinuria characteristics. Methods: Data of 923 type 2 diabetic patients, who were admitted to our Department between January 2000 and December 2008, were analysed retrospectively. The records of 378 patients were included in the study and classified as normoalbuminuric, microalbuminuric and macroalbumhzuric. These groups were compared in terms of demographic, clinical and laboratory findings to investigate the risk factors related to nephropathy. Results: Of the 378 patients, 224 were female (59%) and 154 were male (41%). The mean age was 58.9 +/- 9.7 years. A total of 100 patients (265%) with micro and macroalbuminuria were identified as nephropathic. In the nephropathic group, the levels of FBG (Fasting Blood Glucose), PBG (Postprandial Blood Glucose), HbAl c (Hemoglobin Al c= glycosylated hemoglobin), urea, and creatinine, and the duration of known diabetes were significantly increased when compared with the non-nephropathic group. Diastolic blood pressure and urea levels were significantly higher and creatinine clearance was significantly lower in the macroalbuminuric group. Conclusion: We found a significant relationship between nephropathy and HbAl c, an important indicator of blood glucose control. Therefore, it is essential to provide aggressive blood pressure management and long-term glycaeinic control in order to reduce cardiovascular risk, prevent the development of diabetic nephropathy and ESRF (End Stage Renal Failure), and reduce overall mortality and morbidity. Education of diabetic patients about the risks and complications of elevated blood pressure and poor glycaemic control is a critical component of clinical practice.Öğe THE EVALUATION OF Streptococcus Mutans COLONIZATION IN PRIVATE SCHOOL NURSERY-KINDERGARTEN CHILDREN's TOOTHBRUSH AT DIYARBAKIR REGION(2022) Bucaktepe, Pakize Gamze Erten; Toptancı, İsmet Rezani; Toptancı, Bırcan Çeken; Celepkolu, TahsinAIM: Disinfection of the toothbrush is an essential parameter for oral hygiene. As a result, especially children can not clean their toothbrushes sufficiently after brushing their teeth. The purpose of this study was to evaluate the accumulation level of Streptococcus mutans colonization at private school nursery-kindergarten children's toothbrushes and evaluate the effectiveness of chlorhexidine solution in four weeks for disinfection. METHODS: This study was approved by the local ethics committee. Two hundred thirty-four private school nursery-kindergarten children were selected for this study, who's aged between 24-72 months. These selected children for this study did not have any dental, antibiotic, antimycotic treatment in the last three months. Before the study, a survey was conducted about parents' education, employment, the income. A pediatric dentist made an oral examination of these children, dental caries, fillings, and missing teeth were determined. Children were divided into two groups; toothbrushes, toothpaste, and practical solutions distilled water and %0,12 chlorhexidine gluconate solution was given in a bottle for four weeks. In addition, the toothbrushes of children were collected every week. After incubation, Streptococcus mutans colonization was evaluated under stereomicroscope. All the collected data were statistically evaluated. RESULTS: The DMF-T scores were statistically significant when evaluated with parents' education and income (p<0,05), but there was no statistical relationship between parents' employment and DMF-T scores (p?0,05). Streptococcus mutans colony reduction at the Chlorhexidine group was statistically significant (p<0,05). CONCLUSION: From the first brushing, toothbrushes can be contaminated with bacteria. If the toothbrushes are not clean sufficiently, the bacteria taken from the oral environment have a chance to form a colony on the toothbrushes with the effect of moisture. In addition, Streptococcus Mutans is a bacteria that can stay on toothbrushes and cause re-infection. This study shows that toothbrush disinfection is essential to prevent bacteria from re-infection and contamination of oral flora.Öğe EVALUATION OF THE REACHING TARGET VALUES IN PATIENTS WITH HYPERTENSION AND IMPORTANCE OF TENSION FOLLOW-UP CARDS(Carbone Editore, 2014) Can, Huseyin; Celik, Sercan Bulut; Celepkolu, Tahsin; Akbayin, Zelal; Guclu, Yusuf Adnan; Ongel, Kurtulus; Cakir, LutfullahAim: To detect the efficiancy of the tension follow-up cards, which are used to follow tension, in achieving target values in the treatment of hypertensionl. Material and method: The research planned as a multicenteral, noninterventional observe and follow-up. was made in IS different Family Health Care units in different 7 cities, in Turkey, between November 2011 and April 2012. Patients diagnosed as essential hypertension and who were already taking at least one antihypertensive medicine, who were above 18 years old, were informed about the study and accepted 529 patients were involved into the study The patients involved were divided into two groups as experimental group and control group. The patients in the experimental group were given,a tension follow up card while the control group were not Both of the groups were given appoinments for control at the end of the fourth week. For statistical analysis, chi-square test, t-test and multiple variable logistic regression analysis were used. Results: Study was performed on 529 hypertensive patients; 247 (46.7%) were in the experimental, 282 (53.3%) were in the control group. In total; 332 patients (62.8%) were women and 197 patients (37.2%) were men. Mean age for the patients was 58.15 +/- 10.68 (mm 32 max:90) and mean body mass index was 30.76 +/- 5.18 (min:18.31 max 52.07) No statistical difference Was found between experimental and control groups for the begining tension values, except for the first visit first systole measurement. After one month, all measurements were repeated. For all measurements in the second visit, tension values of the experimental group were statistically lower than the control group (p<0.00 I). Conclusion: Patients who get treatment for hypertension but don't reach target blood pressure values constitudes high risk in the society. Data obtained from the study showed that; to control hypertension effectively, patients must be under control and must participate in the follow-up actively.Öğe Fibromyalgia incidence among patients with hepatitis B infection(Wiley, 2016) Yazmalar, Levent; Deveci, Ozcan; Batmaz, Ibrahim; Ipek, Davut; Celepkolu, Tahsin; Alpayci, Mahmut; Hattapoglu, ErkamAim: The purpose of our investigation was to evaluate the incidence of fibromyalgia syndrome (FMS) and identify FMS-related clinical symptoms in hepatitis B virus (HBV) patients. Methods: One hundred and eighteen HBV surface antigen (HbsAg)-positive patients (40 with chronic active hepatitis B, 40 hepatitis B carriers and 38, all of whom had been antiretroviral-treated for at least 3 months) were included in this study. In addition, 60 age- and gender-matched HbsAg-negative healthy controls were included in the study. Results: There was no significant difference in age, gender or body mass index (BMI) between the two groups (P > 0.05). Serum aspartate aminotransferase and alanine aminotransferase levels were significantly higher in HBV patients relative to the control group (P < 0.05). The incidence of FMS, widespread body pain, fatigue, sleep disturbance, anxiety, morning stiffness, arthralgia was significantly greater among HBV patients relative to the control group. Additionally, the mean tender point counts and the visual analog scale values were significantly higher among the HBV patients (P < 0.05). Conclusions: The results of the present study demonstrate that FMS incidence is greater among HBV patients relative to control subjects. However, there were no differences in FMS incidence among the subgroups of HBV diagnoses.Öğe Increased fibrinogen, D-dimer and galectin-3 levels in patients with migraine(Springer-Verlag Italia Srl, 2014) Yucel, Yavuz; Tanriverdi, Halis; Arikanoglu, Adalet; Varol, Sefer; Kaplan, Ibrahim; Akil, Esref; Celepkolu, TahsinThere are limited studies evaluating the fibrinogen levels in patients with migraine. It remains unknown whether the levels of the haematological marker of thromboembolism, d-dimer, and the levels of galectin-3, which plays an important role in inflammation as a proinflammatory mediator, change during the attacks in patients with migraine. The present study aims to compare galectin-3, fibrinogen and d-dimer levels in patients with migraine during the attacks and interictal periods, and to compare galectin-3, fibrinogen and d-dimer levels between patients with migraine and healthy controls to investigate the role of these parameters in the pathogenesis of migraine. Fifty-nine patients with migraine and 30 age-gender matched healthy control subjects were enrolled in the study. Blood galectin-3, fibrinogen and d-dimer levels were measured in patients with migraine. Patients with migraine had higher levels of galectin-3, fibrinogen and d-dimer compared to the healthy controls (p < 0.05). No statistically significant difference was found between galectin-3 and fibrinogen levels during the attacks and interictal period in the migraine group (p > 0.05). Migraine patients had higher d-dimer levels during the attacks compared to the patients in the interictal period in the migraine group (p = 0.05). In conclusion, we found increased levels of fibrinogen, d-dimer and galectin-3 in patients with migraine compared to the healthy control group. Furthermore, we showed increased galectin-3 levels in patients with migraine, and higher d-dimer levels during migraine attacks compared to the interictal periods for the first time. These findings may be associated with the hypercoagulability and neurogenic inflammation during migraine headaches.Öğe Investigation of Mean Platelet Volume and Platelet Count in the Blood of Patients with Migraine(Turkish Neurological Soc, 2013) Varol, Sefer; Akil, Esref; Cevik, Mehmet Ugur; Celepkolu, Tahsin; Yucel, Yavuz; Tanriverdi, Mehmet Halis; Aluclu, Mehmet UfukObjective: Mean platelet volume (MPV) is an indicator for platelet function and activation. Studies researching MPV and platelet level on the patients with migraine are insufficient. In this study, we aimed to find a difference in MPV and platelet count in individuals with migraine compared to healthy controls, which are indicators for platelet activation. Material and Method: We recruited 193 patients (female/male: 128/65, average age: 31.66 +/- 9.01) who are referred to the Neurology Clinic of Dicle University, Faculty of Medicine between January 2010 and January 2012 and have been diagnosed with migraine according to 2004 diagnostic criteria of International Headache Society (IHS) and 119 healthy individuals (female/male: 73/46, averge age: 32.27 +/- 9.88) who are referred to the Family Practice Clinic and Blood Bank. We compared MPV and platelet counts between the patients with migraine and healthy controls. Both groups were similar in terms of age and gender. Results: A statistically insignificant increase was found in MPV in patients with migraine (7.98 +/- 1.34 fL) when compared to the control group (7.85 +/- 0.96 fL) (p=0.34). Platelet levels were significantly lower in patients with migraine (367.6 +/- 74.2) than the platelet levels of the control group (286.9 +/- 68.3) (p=0.02). Discussion: We found lower platelet levels in the patients with migraine compared to the control group. There was also statistically insignificant increase in MPV in patients with migraine, suggesting that these findings may indicate an insignificant platelet activation in patients with migraine. New prospective studies are needed on this subject.Öğe Lipid panel with Non-HDL cholesterol and total cholesterol/HDL cholesterol ratio(Bolu Abant İzzet Baysal Üniversitesi, 2015) Yüksel, Hatice; Kaplan, İbrahim; Celepkolu, Tahsin; Toprak, Gülten; Aydeniz, Nurefşan; Etik, Emel; Çolpan, LeylaOBJECTIVE: In our study, the importance of the computational tests such as non-HDL cholesterol and Total cholesterol to HDL ratio for evaluating blood lipid levels were investigated.METHODS: The measured and calculated lipid parameters of 683 patients whose test inputs were done from Family Medicine Clinic were evaluated. The number of the patients were determined who had high Non-HDL cholesterol and total cholesterol / HDL cholesterol however the the routine lipid parameters were in the acceptable range.RESULTS: According to our results, 45 6.6% patients had high non-HDL cholesterol values and 127 %18,6 patients had high TC / HDL-cholesterol levels. Also, there were 11 1.6% patients with high non-HDL-cholesterol levels, and 39 %5,7 patients with high TC / HDL cholesterol ratio, while all routine lipid parameters were in acceptable limits. CONCLUSION: The addition of Non-HDL cholesterol and TC / HDL-cholesterol ratio to routine laboratory results would be beneficial because it can create an alert to clinicians in terms of lipid disorders.Öğe Low fetuin-A level in migraine: a case-control study(Springer-Verlag Italia Srl, 2014) Tanriverdi, Mehmet Halis; Varol, Sefer; Arikanoglu, Adalet; Bucaktepe, Pakize Gamze Erten; Celepkolu, Tahsin; Akil, Esref; Yuksel, HaticeMigraine is a type of primary headache which is caused by the alterations in trigeminovascular system. Migraine attacks are associated with neurovascular inflammation of the cerebral and extracerebral vessels, but its pathophysiological mechanisms have not still been fully delineated. Also, migraine has been found to be associated with higher risks for various metabolic disorders. Thus, we aimed to investigate the matrix metalloproteinases (MMP), fetuin-A, ghrelin, and omentin levels which have important roles in metabolic disorders and inflammation, and to examine their relationship with migraine subtypes and attack frequency. Forty-nine migraine patients and 30 age- and sex-matched healthy control subjects were enrolled. Migraine diagnosis was confirmed according to the International Classification of Headache Disorders-II diagnostic criteria. Analyses of MMP9,MMP3, ghrelin, omentin, and fetuin-A were performed by the ELISA method. Fetuin-A, MMP-9, and MMP-3 levels were significantly lower in migraine than controls (p < 0.05). There were no significant differences between groups with respect to omentin and ghrelin (p > 0.05). In migraine patients, serum fetuin-A levels were positively correlated with MMP-9 and negatively correlated with MMP-3. MMP-3, MMP-9, fetuin-A, omentin and ghrelin levels did not correlate with age, disease duration, or frequency of migraine headache (p > 0.05). Migraine patients have lower fetuin-A, MMP-3 and MMP-9 levels than healthy individuals. Migraine patients have low fetuin-A levels, which may be related to the pathogenesis of migraine. The importance and impact of our findings on the pathogenesis, characteristics, and treatment of migraine needs to be investigated in further detailed studies.Öğe A microbiological assessment of the oral hygiene of 24-72-month-old kindergarten children and disinfection of their toothbrushes(Biomed Central Ltd, 2014) Celepkolu, Tahsin; Toptanci, Ismet Rezani; Bucaktepe, Pakize Gamze Erten; Sen, Velat; Dogan, Mehmet Sinan; Kars, Veysel; Aslanhan, HamzaBackground: The objective of this study is to assess the index of decayed, missing and filled teeth (DMF-T), habit of brushing teeth, and the microbiological agents accumulating on the children's toothbrushes for 4 weeks and response of these agents to disinfection via a chlorhexidine solution, then compare those results with the education and income levels of the children's parents. Method: Included in the study were 187 children (96 in the control group and 91 in the experiment group - chlorhexidine) chosen randomly from 600 kindergarten children whose ages ranged from 24 months to 72 months. The children selected had not taken any antibiotics, antimicotics for three months and dental treatments during this trial. The distribution of these children to the groups was also done randomly. After performing a survey for the education, occupation, and income status of the parents, the children were examined and the number of decayed teeth was recorded. The children were given toothbrushes, toothpaste (with fluroide), and the solutions (including distilled water and chlorhexidine) for four weeks under the condition that toothbrushes were returned at the end of each week. The 14 different microbiological agents observed as a result of the assessment of the samples taken in the first week were also included in the assessments of the samples taken over the four-week period. Results: The decrease in the DMF-T index was found to be meaningful according to the differences in education, income, and occupation status of the parents. Of all the samples taken from the toothbrushes, the bacteria with the greatest rate of reproduction included Streptococcus mutans, Escherichia Coli, Pseudomonas aeuroginosa, Enterococcus spp, Staphylococcus epidermidis and Candida albicans. Except for Candida albicans, the other microorganisms taken as samples from the toothbrushes reproduced less overall. In the group using the solution with chlorhexidine, a meaningful decrease in bacterial reproduction was discovered compared to the control group. Conclusion: The findings of this study show that the education, occupation, and socioeconomic situations of the parents should be considered when discussing children's oral and dental health. Moreover, the study shows that disinfection of toothbrushes in order to prevent reinfection and contamination oral flora with the bacteria again is important in terms of preventive medicine and family-children health.Öğe Non-Valvular Atrial Fibrillation in the Elderly; Preliminary Results from the National AFTER (Atrial Fibrillation in Turkey: Epidemiologic Registry) Study(Elsevier Science Inc, 2013) Ertas, Faruk; Oylumlu, Mustafa; Akil, Mehmet Ata; Acet, Halit; Bilik, Mehmet Zihni; Celepkolu, Tahsin; Yildiz, Abdulkadir[Abstract Not Available]Öğe Novel FGF10 mutation in autosomal dominant aplasia of lacrimal and salivary glands(Springer Heidelberg, 2017) Seymen, Figen; Koruyucu, Mine; Toptanci, Ismet Rezani; Balsak, Selahattin; Dedeoglu, Serkan; Celepkolu, Tahsin; Shin, Teo JeonAplasia of lacrimal and salivary glands (ALSG) is a rare autosomal dominant inherited disease, characterized by aplasia, atresia, or hypoplasia of the lacrimal and salivary systems with variable expressivity. The purpose of this study was to identify genetic etiology of an ALSG family. We recruited a Turkish family with ALSG and performed a mutational analysis, based on the candidate gene approach, to clarify the molecular genetic etiology. The candidate gene sequencing of the FGF10 gene identified a novel heterozygous nonsense mutation (c.237G > A, p.Trp79*) in the exon 1. The identified novel mutation would result in a haploinsufficiency of the FGF10, because of nonsense-mediated mRNA decay caused by a premature stop codon. This report further confirms that ALSG is caused by the haploinsufficiency of functional FGF10. Identification of the genetic etiology of the ALSG will help both the family members and dentist understand the nature of the disorder. Therefore, it will positively motivate oral health care to avoid further destruction of the tooth due to the lack of salivary production.Öğe Protective Effect of Caffeic Acid Phenethyl Ester on Oxidative Stress in Diabetic Rat Sciatic Nerve(Asian Network Scientific Information-Ansinet, 2012) Yucel, Yavuz; Celepkolu, Tahsin; Kibrisli, Erkan; Kilinc, Faruk; Beyaz, Coskun; Aluclu, Mehmet Ufuk; Basarili, Mustafa KemalThere has been no report which investigates the effects of Caffeic Acid Phenethyl Ester (CAPE) on elevated levels of oxidative stress in sciatic nerve tissues of diabetic rats. Therefore, this study was undertaken to determine whether CAPE, by virtue of its antioxidant properties, could affect lipid peroxidation, nitric oxide (NO), Paraoxonase (PON-1) and the oxidant/antioxidant balance in the sciatic nerve of Streptozotocin (STZ)-induced diabetic rats. The rats were treated as follows: control; this group of rats (n = 9) received isotonic solution. Diabetic (STZ, untreated diabetic): STZ 50 mg kg(-1) b.wt. was given intraperitoneally for the induction to this group (n = 8). Diabetic+CAPE treatment (STZ+CAPE, CAPE-treated diabetic): diabetic rats (n = 8) received CAPE (10 mu mol/kg/day) for a period of 21 days beginning one week after the STZ administration. Biomarkers; Malondialdehyde (MDA), Total Oxidant Status (TOS), total antioxidant status (TAS), PON-1 and NO levels for oxidative stress in sciatic nerve of the rats were measured. We found a significant increase in MDA, NO and TOS levels along with a reduction in TAS levels and PON-1 activity in the sciatic nerves of the STZ-induced diabetic rats (at p<0.001). The MDA, TOS and NO levels in sciatic nerve were significantly reduced in the CAPE-treated diabetic group compared to the untreated diabetic group (at p<0.05). In conclusion, the results of this study demonstrated that CAPE exhibits protective effects against oxidative damage in the sciatic nerve tissues of diabetic rats.Öğe RADIOLOGICAL DAMAGE IN RHEUMATOID ARTHRITIS: RELATIONSHIP BETWEEN THE DURATION OF MORNING STIFFNESS, DEPRESSIVE SYMPTOMS, AND DISEASE DURATION(Carbone Editore, 2015) Celepkolu, Tahsin; Sariyildiz, Mustafa Akif; Yazmalar, Levent; Bucaktepe, P. Gamze Erten; Cetincakmak, Mehmet Guli; Satici, OmerAims: The aim of this study was to evaluate radiological damage and disease-related variables in patients with rheumatoid arthritis (RA). Material and methods: Ninety patients diagnosed with RA were enrolled in this cross-sectional and descriptive study. All of the patients were assessed using the Rheumatoid Arthritis Quality of Life and Health Assessment Questionnaire scales and the Beck Depression Inventory. The Disease Activity Score 28 scale was used to assess disease activity, and antibodies against mutated citrullinated vimentin (Anti MCV) were identified with an Enzyme-Linked Immuno Sorbent Assay. Radiological damage was calculated with the modified Larsen method. Results: According to the suggested Cut-off point for the Larsen score (scores >= 28), 35.5% (n=32) of the patients with RA had an erosive score. The patients with erosive RA had significantly higher Anti MCV, disease duration and Beck depression scores than did the non-erosive RA group. Multivariate regression analyses indicated that the Beck depression score, disease duration and duration of morning stiffness were independently associated with the radiological score. Conclusion: Radiological damage in RA patients is a result of multifactorial origins and is associated with disease-related variables such as disease duration, duration of morning stiffness, Anti- Cyclic citrullinated peptide levels and depressive symptoms.Öğe The Reasons of Vaccination Rejection during the Mop-up Oral Polio Vaccination Campaign: A Family Health Center Experience(Duzce Univ, 2017) Erdem, Ozgur; Toktas, Izzettin; Celepkolu, Tahsin; Demir, VasfiyeObjective: Mop-Up Polio Vaccination Campaign is a movement which goals to reach the target of eliminating polio. Our aim in this study is to determine the characteristics of the families who have rejected oral polio vaccination (OPV) of their children within the OPV Campaign in a family health center and to examine the reasons of rejecting the vaccination. Methods: The data was obtained through a survey in face-to-face interviews which were performed with the families who have rejected the vaccination of their children within the Mop-Up Oral polio vaccination campaign. The survey form consisted of 14 questions about the socio-demographic features of the families and children, and the reasons of refusing oral polio. Results: 1250 children were included in the vaccination program during the campaign. 38 families of the children (3.04%) declined vaccination during the campaign, the average age of the children were 23.2+/-17.7 months. The youngest one was three days old and the eldest one was 59 months old. Looking over the family members who took the survey, it is seen that 71 % of those were the mothers (n=27), 8% of those were the fathers (n=3) and 21% of those were the relatives (n=8). It was discovered that 94.7 % of the families of the children who rejected OPA vaccination got other vaccinations according to the Ministry of Health National Vaccination Calendar (n=36), whereas 5.3% of those children lacked of other vaccinations (n=2). Though 81.6% of the children were given OPA beforehand (n=31), 18.4% were not given at all (n=7). Conclusion: Levels of educational and awareness are important in reaching the targeted vaccination rates in the conduction of vaccination works. We believe that on the vaccination campaigns to be conducted, informing the families about vaccination and increasing their awareness will decrease the vaccination rejections.Öğe The Relationship between Obesity and Cardiovascular Risk in Postmenopausal Women(Duzce Univ, 2019) Bucaktepe, Pakize Gamze Erten; Celepkolu, Tahsin; Aslan, Ilknur; Tanriverdi, M. Halis; Yilmaz, Ahmet; Aslanhan, Hamza; Kars, VeyselObjective: The aim of this study was to investigate the relationship between obesity and cardiovascular risk in postmenopausal women. Methods: The study included 43 postmenopausal women who were admitted to Dicle University Medical School Family Medicine Outpatient Clinic. Body mass index (BMI), waist and hip circumferences, body fat mass and percentage, 24-hour arterial tension measurements, homocysteine (Hcy), lipid and vitamin B12 levels, and Framingham risk score (FRS) were compared between obese (BMI >= 30 kg/m(2)) and non-obese (BMI<30 kg/m(2)) patients. Results: The patients included 25 (58.1%) obese and 18 (41.9%) non-obese patients. Abdominal obesity was seen in 29 (67.4%) and truncal obesity in 18 (41.9%) participants. Family history of cardiac disease was seen in 25 (58.1%) women, most of whom were obese. Based on FRS, moderate cardiovascular risk was assessed in 21.6%, but none of the participants were at high risk. FRS was positively correlated with Hcy and waist/hip ratio. Conclusions: The results of this study indicate that age- and gender-dependent differences must be taken into consideration for cardiovascular risk assessments and postmenopausal women should be informed about obesity and hypertension in order to improve their quality of life.Öğe Sleep quality in patients with systemic sclerosis: relationship between the clinical variables, depressive symptoms, functional status, and the quality of life(Springer Heidelberg, 2013) Sariyildiz, Mustafa Akif; Batmaz, Ibrahim; Budulgan, Mahmut; Bozkurt, Mehtap; Yazmalar, Levent; Inanir, Ahmet; Celepkolu, TahsinThe aim of this study is to evaluate the relationship between the sleep quality and the disease-related variables, functional status, quality of life, and depressive symptoms in patients with systemic sclerosis (SSc). Forty-eight patients diagnosed with SSc and 42 healthy control subjects were enrolled in the study. The demographic and clinical characteristics of the patients such as the Raynaud's phenomenon, SSc subtype, digital ulcers, gastrointestinal and lung involvement, and disease activity were recorded. All patients were assessed using the short form 36 (SF-36) quality of life scale, the health assessment questionnaire and the beck depression inventory. Generalized pain and fatigue were assessed with the Visual Analoge Scale. For the evaluation of the sleep disturbance, the SSc and control groups were assessed with the help of the Pittsburgh Sleep Quality Index (PSQI). The patients with SSc had significantly higher scores in the subjective sleep quality, sleep latency, habitual sleep efficiency, sleep disturbance, daytime dysfunction domains, and in terms of the total PSQI score compared to the healthy control group (p < 0.05). According to the results of spearman's analysis, there was a significantly higher correlation between the generalised pain, fatigue, depressive symptoms, functional status, and physical score of the SF-36 and the sleep disturbance (p < 0.01). There was also a significantly lower correlation between the menopause status, dyspnoea, gastroesophageal reflux, dysphagia, the mental score of the SF-36, and the sleep disturbance (p < 0.05). The sleep quality is disturbed in patients with SSc. The lower quality of sleep is especially associated with the pain, fatigue, depressive symptoms, and functional status.Öğe Smoking habits of nurses and midwives and their attitudes tobacco control; a primary care based study from four major cities of Turkey(Drunpp-Sarajevo, 2012) Aydin, Leyla Yilmaz; Baltaci, Davut; Ozturk, Serkan; Saritas, Ayhan; Eroz, Recep; Celepkolu, Tahsin; Yilmaz, AylinIt was aimed to investigate smoking habits, knowledge about and attitudes towards tobacco control among nurses and midwifes at primary care settings in Turkey. A cross-sectional survey was applied to nurses/midwives at primary care settings. 1063 surveys were analyzed in the study. Mean age of nurses/midwives was 33.7 +/- 6.3. Current, former and never smokers' ratio among nurses/midwives were 30.1 %, 10.6 % and 59.3 %, respectively. Knowledge of nurses/midwives was observed as quite high. Majority of never smokers significantly marked as higher agreement with items related to knowledge level about smoking by than ever smokers. The lowest ratio was observed in agreement with item of Pharmacotherapy is efficient for smoking cessation (46.6 %). the highest ratio was observed in agreement with item of Health professionals should routinely advise patients to avoid smoking around their children (97.5 %). Significant differences were observed in statement of agreement with items related to attitudes of the nurses/midwives towards smoking and tobacco control between never and ever smokers. Almost all of the nurses/midwives had no any training course on smoking cessation practice (99.6 %). Majority of them were not competent for preparedness in smoking cessation (competent: 17.4 % vs. incompetent or somewhat: 82.6 %). In conclusion, knowledge and skills in smoking cessation practice and attitudes towards smoking and tobacco control in nurses/midwives were observed as low and somewhat high. Therefore, an appropriate education program should be instituted to increase motivation of them about their role in society and smoking cessation practice.
