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    Histological Changes in the Gingival Tissues of Rats Subjected to Surgical Extraction of the Adrenal Glands
    (Medwell Online, 2009) Dag, Ahmet; Ketani, Muzaffer Aydin; Zengingul, Ali Ihsan; Uysal, Ersin; Baskan, Zelal
    Hormones are specific regulatory molecules that have potent effects on the major determinants of the development and the integrity of the skeleton and oral cavity also including periodontal tissues. The aim of this study, is to investigate the effect of adrenalectomy on rat gingival tissue. Twenty-eight mature Wistar albino female and male rats divided randomly into 2 groups and in one group adrenalectomy was performed. After 21 days recovery period, Control and Experimental groups were sacrificed under Ketamin HCi anesthesia and clinical and histological observations were made. Microscopic findings, revealed significant changes in adrenalectomized rats. Hypertrophy and thickness of gingival epitelium was apparent in the gingival epithelium of ADX group. Increase in mitotic activity in stratum basale layer of gingival epitelium and increase in keratinisaton layer were observed in adrenalectomized rats. A decrease in collagen fibrils and irregularity of papilla was seen in adrenalectomized rats. Our findings demonstrate the importance of adrenal glands in the development of gingival tissue and suggest that adrenal glands deficiency is one mechanism, by which gingival disorder susceptibility may be increased.
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    Hypohidrotic ectodermal dysplasia: A case report
    (Quintessence Publishing Co Inc, 2008) Yavuz, Izzet; Kiralp, Suha; Baskan, Zelal
    Ectodermal dysplasias represent a large and complex group of diseases comprising more than 170 clinical conditions. They are caused by impaired development of the ectodermal appendages and characterized by a primary defect in at least one of the following tissues: nails, hair, sweat glands, or teeth. Ectodermal dysplasia has emotional consequences for affected individuals at early ages. This case report outlines a possible routine approach to restoring function and esthetics and aiding in the social interaction for a 9-year-old girl diagnosed with hypohidrotic ectodermal dysplasia at about 7 years of age.