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Öğe An Analysis on Aerodynamic and Acoustic Changes After Thyroidectomy(Int College Of Surgeons, 2016) Yilmaz, Beyhan; Bakir, Salih; Yilmaz, Edip Erdal; Senhul, Engin; Uslukaya, Omer; Gul, Aylin; Ozkurt, Fazil EmreThe purpose of this study was to investigate the aerodynamic and acoustic changes after thyroidectomy without laryngeal nerve injury by using objective methods. Voice samples of sustained /alpha/ recorded from 44 adults preoperatively and nearly 1 week and 3 months after thyroidectomy were analyzed for mean vocal fundamental frequency (Mean Fo, Hz), maximum fundamental frequency (Max Fo, Hz), minimum fundamental frequency (Min Fo, Hz), jitter, shimmer, glottal to noise excitation ratio (GNE), irregularity, noise, overall severity, S time, Z time, S/Z ratio, and maximum phonation time (MPT). Voice samples were analyzed using the lingWAVES software. The comparisons of preoperative and early and late postoperative acoustic parameters revealed significant differences in Mean F0, Max F0, MPT, and S Time between the early and late postoperative periods. The voice changes after thyroidectomy were not affected by age, sex, or surgical procedure, but they differed between the benign and malignant nature of the tumor. Patients with malignant tumors showed a greater decrease in Mean F0 and Max F0 compared with the patients with benign tumors, and this difference was statistically significant. Voice changes may occur after thyroidectomy even in the patients with no evidence of laryngeal nerve damage, and these changes can be assessed with objective measurement methods. This information should be explained to the patients during the preoperative counseling, and proper informed consent is ethically and legally required for all planned thyroidectomies.Öğe Commentary: Diagnostic importance of radiologic evaluation in deep neck infections(W B Saunders Co-Elsevier Inc, 2012) Bakir, Salih[Abstract Not Available]Öğe Course anomalies of extracranial internal carotid artery and their relationship with pharyngeal wall: an evaluation with multislice CT(Springer France, 2012) Ekici, Faysal; Tekbas, Guven; Onder, Hakan; Gumus, Hatice; Cetincakmak, Mehmet Guli; Palanci, Yilmaz; Bakir, SalihThe goal of our study was to measure the prevalence of anomalies in the extracranial segment of internal carotid artery (ICA), to measure the carotid-pharyngeal distance (CPD). Computed tomography (CT) angiography images of 607 patients were retrospectively examined. The course anomaly and CPD were obtained at different image plane. The patients were divided into four groups according to their age. The incidence of course anomaly in ICA was shown to be 60.3 %. Prevalence of course anomaly showed an increase with age (p < 0.001). Women had more ICAs with a course anomaly than men (p < 0.001). Mean CPD among all ICAs was found to be 11.13 mm. When CPD values were compared between the groups, group 1 and group 2 did not have a significant difference, however, there was a significant difference between other groups (p < 0.05). The CPD significantly decreased with age (p < 0.001). In ICAs that showed a straight course, the mean CPD was 13.0 mm, while in ICAs that showed course anomaly, the mean CPD was determined to be 9.49, showing a significant difference (p < 0.05). In conclusion, the number of ICAs that show a course anomaly increases with age, while the CPD decreases. The CPD is decreased in groups that show anomalies. The detection of a decreased CPD before surgery may lower the chance of a perioperative hemorrhage due to artery damage during pharyngeal procedures. Hence, while reporting neck CT angiographies, it may be valuable to also report the presence of ICA anomalies and CPD.Öğe Cultural adaptation of an olfactory test: the odour in bottle test (vol 52, pg 172, 2014)(Int Rhinologic Soc, 2014) Gul, Aylin; Akdag, Mehmet; Ozkurt, Fazil Emre; Yilmaz, Beyhan; Sengul, Engin; Bakir, Salih; Topcu, Ismail[Abstract Not Available]Öğe Deep neck space infections: a retrospective review of 173 cases(W B Saunders Co-Elsevier Inc, 2012) Bakir, Salih; Tanriverdi, M. Halis; Gun, Ramazan; Yorgancilar, A. Ediz; Yildirim, Muzeyyen; Tekbas, Guven; Palanci, YilmazPurpose: The purpose of this study is to review our recent experience with deep neck infections and emphasize the importance of radiologic evaluation and appropriate treatment selection in those patients. Materials and Methods: The records of 173 patients treated for deep neck infection at the Department of Otolaryngology and Head and Neck Surgery of Dicle University Hospital during the period from 2003 to 2010 were retrospectively reviewed. Their demography, symptoms, etiology, seasonal distribution, bacteriology, radiology, site of deep neck infection, durations of the hospital admission and hospital stay, treatment, complications, and outcomes were evaluated. The findings were compared to those in the available literature. Results: Dental infection was the most common cause of deep neck infection (48.6%). Peritonsillar infections (19.7%) and tuberculosis (6.9%) were the other most common cause. Pain, odynophagia, dysphagia, and fever were the most common presenting symptoms. Radiologic evaluation was performed on almost all of the patients (98.3%) to identify the location, extent, and character (cellulitis or abscesses) of the infections. Computed tomography was performed in 85.3% of patients. The most common involved site was the submandibular space (26.1%). In 29.5% of cases, the infection involved more than one space. All the patients were taken to intravenous antibiotic therapy. Surgical intervention was required in 95 patients (59.5%), whereas 78 patients (40.5%) were treated with intravenous antibiotic therapy alone. Life-threatening complications were developed in 13.8% of cases; 170 patients (98.3%) were discharged in stable condition. Conclusion: Despite the wide use of antibiotics, deep neck space infections are commonly seen. Today, complications of deep neck infections are often life threatening. Although surgical drainage remains the main method of treating deep neck abscesses, conservative medical treatment are effective in selective cases. (C) 2012 Elsevier Inc. All rights reserved.Öğe Does usage of a room air freshener affect the nasal mucosa?(Sage Publications Inc, 2014) Akdag, Mehmet; Bakir, Salih; Alabalik, Ulas; Ozkurt, Fazil Emre; Topcu, IsmailBackground: Effects of chemicals emitted from the room air freshener sprays (RAFSs) on nasal mucosa are still unclear. The purpose of this study was to investigate effects of RAFSs on the nasal mucosa of rats for different time intervals. Methods: Twenty-eight rats were randomly divided into four experimental groups: group 1 (n = 7) was the control group and not exposed to RAFS or other chemicals, group 2 (n = 7) was exposed to RAFS for 1 month, group 3 (n = 7) was exposed to RAFS for 2 months, and group 4 (n = 7) was exposed to RAFS for 3 months. Samples from the nasal septum were stained using hematoxylin and eosin solution, examined by a pathologist using a light microscope, and analyzed with Fisher's exact test. Results: We observed that distinct histopathological differences in the nasal mucosa of exposed rats depends on different time intervals (p < 0.05). Increased congestion was found after the 1st month of exposure (group 2). Although edema and mild inflammatory cell infiltration, including some eosinophils, was seen after the 2nd month (group 3), squamous metaplasia, numerous eosinophils, and intense inflammatory cell infiltration began after 3 months of exposure (group 4). Conclusion: Our results showed that continuous use of RAFS can cause inflammation and eosinophilic infiltration in rats, which begins after 2 months of exposure and may lead to metaplasia after 3 months. Because of differences in body size, geometry, and physiological responses of rats, the extrapolation of these results to humans is not straightforward. However, any such comparison should be made with caution. Finally, more performance is necessary to clarify this subject.Öğe Effect of cigarette smoking on nasal mucociliary transport rate: Rhinoscintigraphic evaluation with using 99mTc-macroaggregated albumin(Drunpp-Sarajevo, 2012) Dostbil, Zeki; Dag, Yusuf; Abakay, Abdurrahman; Bakir, Salih; Sezgi, Cengizhan; Abakay, Ozlem; Sen, HadiceObjectives: Cigarette smoking has harmful effects on mucociliary transport (MCT) in respiratory system. We aimed to investigate the association between nasal mucociliary transport rate (NMTR) and duration and amount of smoking in chronic cigarette smokers. Materials and Methods: Fifty four current cigarette smokers and 40 healthy non-smokers were included in this study. In all cases, we measured the NMTR using Tc-99m-macroaggregated albumin (Tc-99m-MAA) rhinoscintigraphy. Results: The mean NMTR of the smokers was lower than that of the healthy non-smoker controls (5.63 +/- 2.78; 9.44 +/- 2.09, respectively) (p<0.0001). There were not statistically significant correlation between NMTRs and year of smoking, and smoking pack-year in smokers (p>0.05; r=0.003, r=-0.2, respectively) whereas there was a statistically significant correlation between NMTRs and cigarettes per day in smokers (p=0.024; r=-0.307). Conclusions: Our findings demonstrated that cigarette smoking decreases the nasal NMTR in chronic term. Impaired mucociliary transport in respiratory system may have harmful effects on the human health. The degree of impairment in NMTRs in smokers may increase as the number of cigarettes per day increases.Öğe The Effect of Corticosteroid Against Streptomycin Ototoxicity(Lippincott Williams & Wilkins, 2013) Kinis, Vefa; Ozbay, Musa; Bakir, Salih; Sengul, Engin; Yorgancilar, Ediz; Keles, Aysenur; Alabalik, UlasThe aim of this experimental study was to determine the possible protective role of corticosteroid in prevention of streptomycin-induced ototoxicity. Twenty-eight adult Wistar albino rats were divided into 4 groups: control (n = 7), streptomycin (n = 7), corticosteroid (n = 7), and streptomycin + corticosteroid (n = 7). Rats were tested with distortion product otoacoustic emissions (DPOAEs) in the beginning and at the end of the study. The animals in all groups were killed under general anesthesia on the 45th day after the last DPOAE measurements. Hearing results were analyzed statistically to determine differences in amplitudes of DPOAE. In addition, the cochleas of each rat were evaluated by histopathologic and immunohistochemical examination. Significant difference was not observed in cochlear hair cells in the control and corticosteroid groups, whereas severe degeneration of hair cells and increased apoptotic cells were observed in the streptomycin group. Moderate degeneration was observed in the streptomycin + corticosteroid group. The hair cells were partially intact. DP-gram of the streptomycin and streptomycin + corticosteroid groups was significantly deteriorated (P < 0.05). The coadministration of steroids with streptomycin, which has a serious ototoxic effect, did not lead to a limitation of this harmful effect.Öğe The Effects of Hyperbaric Oxygen Therapy Against Streptomycin Ototoxicity(Derman Medical Publ, 2014) Bakir, Salih; Ozbay, Musa; Kinis, Vefa; Yorgancilar, Ediz; Gun, Ramazan; Gul, Aylin; Alabalik, UlasAim: Hyperbaric oxygen (HBO) is an important adjuvant therapy and being increasingly used in the treatment of various disorders because of having an important antioxidant activity. This experimental study was designed to determine the possible protective effect of HBO therapy on streptomycininduced ototoxicity. Material and Method: Twenty-eight adult Wistar albino rats were divided into four groups: Streptomycin (n= 7), saline (n= 7), HBO (n= 7), and streptomycin plus HBO (n= 7). The HBO administered rats were placed into a large pressure chamber and received 100% oxygene at 2.5 atmosphere absolute for 60 minutes per day in a period of seven days. Rats were tested with DPOAE (Distortion Product Otoacoustic Emissions) in the beginning and the end of study. The animals in all groups were sacrificed under general anesthesia on the seventh day. Biopsy specimens from inner ear were stored for histopathologic examination with hematoxylin and eosin (H& E) under light microscopy. Results: Outer hair cells shown by light microscopic images were mostly preserved in control and HBO group. DPOAE measurements revealed no significant differences between the beginning and the end (p> 0.05). Streptomycin and streptomycin plus HBO treated rats showed loss of hair cells and auditory functions significantly (p< 0.05). Between the groups of streptomycin and streptomycin plus HBO; there was no statistically significance according to the analysis of the histopathological scores and DPgram results (p> 0.05). Discussion: HBO has probably no harmful effect on hair cells. But it seems to be not beneficial in a streptomycin-induced cochlear damage rat model.Öğe EFFECTS OF HYPERBARIC OXYGEN THERAPY ON RAT NASAL MUCOSA(Diagnosis Press Ltd, 2012) Yorgancilar, Ediz; Tunik, Selcuk; Deveci, Engin; Gun, Ramazan; Bakir, Salih; Kinis, Vefa; Ayaz, ErcanThe objective of this study was to evaluate the histopathologic effects of hyperbaric oxygen (HBO) therapy on the rat nasal mucosa. Twelve adult Sprague-Dawley rats, each weighing 180-220 g, were used as experimental animals. The rats were divided into HBO (hyperbaric oxygen) and control group. The rats in the HBO group (n = 6) were placed into a 20-liter HBO chamber (2.5 atmospheres absolute LAW, 25-26 degrees C with 100 % oxygen) for 90 min per day. The rats received hyperbaric oxygen over a period of 7 days. The rats in the control group (n = 6) were not given HBO. All animals were sacrificed at the end of the study, and nasal tissue samples were prepared. The sections were stained with Haematoxylin and Eosin (H-E), Periodic acid-Schiff (PAS) and Trichrome-Masson to observe the under a light microscope. Immunoreactivity of pseudostratified epithelial cells of the nasal mucosa was assessed with E-cadherin expression by immunohistochemical staining. There were significant differences in the average histopathological score between the groups exposed and non-exposed to HBO. In the HBO group, degenerative changes in epithelial cells were observed. The goblet cells showed expansion of their structure. Mononuclear lymphocyte infiltration, dilation of blood vessels, and hemorrhage were observed in considerable areas of connective tissue. In the immunohistochemical evaluation of E-cadherin expression, there were no significant differences between the two groups. Biotechnol. & Biotechnol. Eq. 2012, 26(6), 3394-3396Öğe The Effects of Systemic Use of Nicotine on the Rat Nasal Mucosa: a Histopathologic and Immunohistochemical Study(Soc Chilena Anatomia, 2012) Yorgancilar, Ediz; Tunik, Selcuk; Deveci, Engin; Gun, Ramazan; Bakir, Salih; Kinis, Vefa; Ayaz, ErcanThe objective of this study was to evaluate the histopathologic effects of systemic use of nicotine on the rat nasal mucosa. Twelve adult Sprague-Dawley rats weighing 180-220 g, were used as experimental animals. The rats were divided into Nicotine and control groups. The rats of Nicotine groups (n=6) were administered 2mg/kg Nicotine sulphate for 28 days. The rats of control group (n=6) were only administered 1,5 ml physiologic saline solution subcutaneously for 28 days. All animals were sacrified at the end of the study and nasal tissue samples were removed and prepared for histologic examination. The sections were stained with Hematoxylin and Eosin (H-E) and Periodic acid-Schiff(PAS) and Trichrome-Masson were observed under light microscope. E-cadherin immunreactivity of pseudostrafied epithelial cells of nasal mucosa was assessed by immunohistochemical staining. There were significant differences in average histopathological score between the groups treated and non-treated to nicotine. In nicotine group, degenerative change of epithelial cells and hypertrophy of goblet cells were observed. Leukocytes infiltration was observed in significant areas of connective tissue. E-cadherin expression was significantly decreased in epithelial cells of the nasal mucosa of Nicotine group.Öğe Evaluation of Hyperactivity, Attention Deficit, and Impulsivity Before and After Adenoidectomy/Adenotonsillectomy Surgery(Lippincott Williams & Wilkins, 2013) Ayral, Muhammed; Baylan, Muzeyyen Yildirim; Kinis, Vefa; Bez, Yasin; Bakir, Salih; Ozbay, Musa; Yorgancilar, EdizObjective: The objective of this study was to determine the severity of attention deficit, hyperactivity, and impulsivity symptoms in patients with obstructive airway problems scheduled to undergo adenoidectomy or adenotonsillectomy operation. The effects of the surgical treatment on these symptoms will also be investigated in a case-control design. Methods: This prospective study included 63 patients (29 girls, 34 boys) who were operated on at the Department of Otorhinolaryngology, Dicle University Medical School, between January 2010 and May 2011 because of obstructive symptoms caused by adenoid or adenotonsillar hypertrophy. The age range of the patients was between 4 and 13 years. The control group consisted of 33 (17 girls, 16 boys) healthy children. Results: Among the patients, 15 children underwent adenoidectomy because of adenoid hypertrophy; 13 patients had adenotonsillectomy because of adenotonsillar hypertrophy, and the remaining patients underwent adenotonsillectomy related with chronic or recurrent tonsillitis with adenoid hypertrophy. Based on the preoperative data, statistically significant difference was observed between the patient and control groups. The patients' attention deficit, hyperactivity, and impulsivity symptoms preoperatively and postoperatively have shown statistically significant differences. Conclusions: Attention deficit, hyperactivity, and impulsivity symptoms were common among the children who show signs of airway obstruction due to adenotonsillar hypertrophy. Adenoidectomy or adenotonsillectomy operations were both observed to be associated with improvement in these symptoms.Öğe Evaluation of the nasal mucociliary transport rate by rhinoscintigraphy in marble workshop workers(Sage Publications Inc, 2011) Dostbil, Zeki; Polat, Cahit; Karakus, Askeri; Bakir, Salih; Yuce, SalimMarble workers are occupationally exposed to intense environmental marble dust in their workplace. We aimed to investigate the effect of occupational marble dust exposure on nasal mucociliary transport rate (NMTR). Seventeen marble workers and 18 healthy controls were studied. In all subjects, NMTRs were measured by Tc-99m-MAA rhinoscintigraphy. NMTRs of workers and control groups were compared by statistically. Mean NMTR was found as 9 +/- 1.8 mm/min in marble workers whereas mean NMTR of healthy controls was 9.6 +/- 2.2 mm/min. There was no statistically significant difference between NMTRs of workers and control groups (p > 0.05). This study has shown that occupationally exposured marble dusts may not cause functional impairment on NMTR in marble workshop workers.Öğe THE HISTOMORPHOLOGIC EFFECTS OF HYPERBARIC OXYGEN THERAPY ON SUBMANDIBULAR, THYROID GLANDS AND TRACHEA(Diagnosis Press Ltd, 2013) Akdag, Mehmet; Gul, Aylin; Bakir, Salih; Ozkurt, Fazil Emre; Alabalik, Ulas; Topcu, IsmailThe aim of this experimental study was to investigate the efficacy of hyperbaric oxygen (HBO) therapy in the neck region of rats based on morphologic changes induced in the exocrine and endocrine glands and trachea. Samples of submandibular glands, thyroid gland and trachea were collected following sacrifice and neck dissection of the animals. The samples were processed for light microscopy and morphometric analysis. HBO administered rats were placed into a large pressure chamber and received 100 % oxygen at 253.3125 kPa (2.5 ata) for 60 min per day for a period of seven days. HBO-treated rats showed no statistically significant differences from the control group, according to the analysis of the histopathological scores (p = 0.930). HBO could probably be considered as neither helpful, nor harmless, on the submandibular glands, thyroid glands and trachea in rats.Öğe HISTOPATHOLOGIC EFFECTS OF GLASS IONOMER BONE CEMENTS APPLICATION TO MAXILLOFACIAL AREA: AN EXPERIMENTAL STUDY IN RABBITS(Diagnosis Press Ltd, 2012) Yorgancilar, Ediz; Firat, Ugur; Gun, Ramazan; Bakir, Salih; Dasdag, Suleyman; Akkus, Zeki; Gokalp, OsmanReconstruction of the maxillofacial bone defects and fractures poses a challenge to the surgeons. Various alternatives and materials have been described for these defects and fractures. Glass ionomer bone cements (GICs) have been used extensively in dentistry but recently they have also been utilized in otolaryngology. We hypothesized that GIC can be an alternative material for maxillofacial reconstruction. However, their biocompatibility is of primary importance because this material will be in direct contact with the tissue for a prolonged tune and might affect it. Therefore the aim of this study was to investigate the tissue responses to GIG in the maxillofacial area in rabbits. The study was carried out on 16 New Zealand White rabbits, which were divided into study (n: 8) and control (n: 8) groups. Experimental defects and fractures were created in the nasal bone, maxilla and zygoma in both the study and the control group. The experimental fractures and defects were reconstructed by GIG in the study group. However, the rabbits in the control group were left to natural healing process. The inflammatory reaction and fibrosis in the rabbits of both the study and the control group were compared by using descriptive histopathological analysis 180 days after application. The tissue reactions were graded. GIG showed a slight inflammatory and fibrous reaction in the rabbit of the study group. Nevertheless, statistical difference between the groups was not observed in terms of inflammatory reaction and fibrosis (P>0.05). The results of this study indicated that GIG is a well tolerated material in maxillofacial reconstruction.Öğe Histopathologic results of long-term sildenafil administration on rat inner ear(W B Saunders Co-Elsevier Inc, 2012) Bakir, Salih; Firat, Ugur; Gun, Ramazan; Bozkurt, Yasar; Yorgancilar, Ediz; Kinis, Vefa; Penbegül, NecmettinObjectives: Sildenafil, a selective inhibitor of phosphodiesterase type 5, is widely used for the treatment of erectile dysfunction. Although cochlear effects of phosphodiesterase type 5 inhibitors remain still unclear because of inadequate data, some evidence that recently emerged indicates that these medications may be responsible for hearing impairment. In the present study, we aimed to examine the histopathologic effects of long-term sildenafil use on the cochlea in a rat model. Methods: The study was performed with adult male Wistar albino rats. The control group was fed on standard laboratory diet. The study group was applied orally with sildenafil therapy, 1.5 mg/kg once a day for 45 days. Rats were anesthetized and decapitated. Each temporal bone was dissected, and the cochleas were removed en bloc. The inner-ear biopsy specimens were examined histologically with hematoxylin and eosin and caspase 3 immunoreaction under light microscopy. Results: Hematoxylin and eosin staining showed no distinctive difference between the control group and the sildenafil group. With immunohistochemical examination, caspase 3 immunoreactivity was observed in the sildenafil group. In the control group, caspase 3 immunoreactivity was not observed. Conclusions: The caspase 3 immunoreactivity in the sildenafil group was strongly associated with an increase in apoptotic events in the cochlea. Long-term use of sildenafil can cause hearing impairment through increased apoptosis. (c) 2012 Elsevier Inc. All rights reserved.Öğe Is there Epithelial Tissue in Bone Pate? A Histopathology Study(Mediterranean Soc Otology & Audiology, 2012) Yorgancilar, Ediz; Firat, Ugur; Alabalik, Ulas; Gun, Ramazan; Yildirim, Muzeyyen; Bakir, Salih; Kinis, VefaObjectives: To evaluate the histology of bone pate collected during mastoidectomy in chronic suppurative otitis media (CSOM) patients with or without cholesteatoma. Study Design: Prospective controlled study. Materials and Methods: The study recruited 32 patients (15 males, 17 females; average age 25.3 (range 19-56 years) who underwent mastoidectomy for CSOM: 16 with cholesteatomas (group I) and 16 controls with granulation or polyp tissue (group II). In all patients, bone pate was collected separately from the mastoid cortex (Level 1), subcortical air cells (Level 2), and just before the antrum mastoideum (Level 3). All samples were stained with hematoxylin-eosin (H&E) and immunochemically with a monoclonal antibody against epithelial membrane antigen (EMA). The presence of squamous epithelium in the bone pate was examined under a light microscope. Results: In Group I, we detected epithelial cells in the bone pate samples obtained from the mastoid subcortex (two of 16 patients) and antrum (four of 16 patients) levels. However, no epithelial cells were observed in bone pate from the mastoid cortex. In the controls (group II), no epithelial tissue was observed in any sample from any level. Conclusions: Epithelial cells can inoculate bone pate collected from the subcortical and antral areas of the mastoid bone in patients with cholesteatomatous CSOM. To prevent epithelial cell inoculation, we recommended that bone pate be collected only from the cortical bone of the mastoid.Öğe Long-term Follow-up Results of the Patients Suffering from Sudden Hearing Loss(Mediterranean Soc Otology & Audiology, 2013) Akdag, Mehmet; Gul, Aylin; Bakir, Salih; Gun, Ramazan; Ozbay, Musa; Kinis, Vefa; Yorgancilar, EdizObjective: The aim of this follow-up study was to evaluate the time-dependent course of hearing recovery in idiopathic SHL patients. Materials and Methods: Forty-four unilateral idiopathic SHL patients treated with the same standard regimen for 10 days were retrospectively reviewed, then they were invited to return to our hospital for their last visit and last audiogram during the study period. Gender, age, duration and severity of hearing loss, the shape of the audiogram and, the presence of tinnitus were evaluated. Thus, the long-term audiometric data, the final hearing outcome and, the rates of hearing recovery was obtained. Results: There was a significant difference in the degree of hearing loss and the rates of hearing recovery between early stage and long-term follow-up (p<0,001). The most common audiogram shape was flat. Hearing was significantly worse in SHL patients with tinnitus compared to SHL patients without tinnitus (p<0,001). Conclusion: Our results revealed that even if the failure of an initial 10-day course of treatment, a delayed recovery continues and there may still be enough time for complete recovery except profound SHL. Tinnitus on presentation with SHL and profound SHL has been identified as a negative prognostic indicator.Öğe Management of Orbital Complications of Sinusitis in Pediatric Patients(Lippincott Williams & Wilkins, 2013) Kinis, Vefa; Ozbay, Musa; Bakir, Salih; Yorgancilar, Ediz; Gun, Ramazan; Akdag, Mehmet; Sahin, MuhammedThe most common reason of orbital infections is sinusitis. Orbital complications of sinusitis are mostly seen in children. Loss of vision and intracranial infections are among the complications of sinusitis. Prompt diagnosis and treatment is very important in the management of orbital complications. The orbital complication can be in the form of cellulitis or abscess. A retrospective review of 26 pediatric patients with orbital complications due to sinusitis was presented in this study. Of 26 patients, there were 13 cases of preseptal cellulitis, 2 cases of orbital cellulitis, and 11 cases of subperiosteal abscess. We grouped the preseptal and orbital cellulites in one category and the subperiosteal abscess in the other. All patients in the cellulitis group recovered by medical treatment. All the patients were treated by surgical drainage. Early diagnosis and appropriate treatment method are vital for the treatment of orbital complications secondary to sinusitis.Öğe Mental health and quality of life in patients with chronic otitis media(Springer, 2013) Bakir, Salih; Kinis, Vefa; Bez, Yasin; Gun, Ramazan; Yorgancilar, Ediz; Ozbay, Musa; Aguloglu, BulentThe present study focused on the comparison of mental health and quality of life (QoL) between chronic otitis media (COM) patients and the hearing population. The patients with chronic otitis media and healthy control group were enrolled in the study. The duration and severity of the auditory impairment were recorded. In addition to hearing loss (HL), the findings of each patient's other ear disorders (ear discharge and tinnitus) were also recorded. In both the groups, psychological symptom profile and health-related QoL were evaluated and compared using a sociodemographic questionnaire, the Symptom Check List 90-Revised Form (SCL-90-R), and the Short Form-36 (SF-36). According to SCL-90-R, somatization (p < 0.001), interpersonal sensitivity (p < 0.001), depression (p < 0.001), phobic anxiety (p < 0.001), and other subscores, and also global severity index score (p < 0.001) were significantly high in patient group when compared to the control group. The patients with COM reported significantly lower levels of QoL in terms of physical role difficulty (p < 0.001), general health perception (p < 0.004), social functioning (p < 0.001), and mental health (p < 0.017) than those of control subjects. Our results indicated that COM patients with mild or moderate HL have poorer life quality and higher psychological problems. Psychological well being should be also considered in assessment of COM patients in addition to the clinical evaluation and audiological tests.
