Yazar "Azizoǧlu, Mustafa" seçeneğine göre listele

Listeleniyor 1 - 4 / 4
  • Küçük Resim
    Öğe
    The cause of depression in adolescence: peer bullying
    (2023) Karabel, Müsemma Alagöz; Arslan, Serkan; Şimşek, Ş.; Azizoǧlu, Mustafa
    OBJECTIVE: Depression affects adolescents worldwide and often predicts more serious disease manifestations in later lifetimes. Peer victimization or bullying, another form of child abuse, increases symptoms of depression. In this paper, the relationship between peer bullying and depression in adolescence was investigated. SUBJECTS AND METHODS: Each adolescent who was admitted to the adolescent unit completed forms referred to as the ‘Depression Scale For Children’ and the ‘Multidimensional Peer Victimization Scale’. Sociodemographic features and results of the scales’ evaluation were studied. SPSS 16.0 program was used for statistical analysis. The p-value below 0.05 was considered statistically significant. RESULTS: 239 adolescents, 120 of whom were male, were investigated. A positive relationship was determined among total and subscale scores of peer victimization-determining scale and depression scale scores. A negative relationship was determined between height, weight, age of the child, and sub-scale score of threat/intimidation. Both the total score of the peer victimization-determining scale and subscale scores of ridicule, open attack, and relational attack pertaining to patients with depression proved to be significantly higher than in those without depression. CONCLUSIONS: The awareness of educators and parents, notably adolescents, must be raised in regard to peer victimization, and activities for increasing the communicative skills of adolescents and for allowing them to be able to express their emotions should also be performed. Identifying and preventing peer victimization, one of the causes of depression, and launching the treatment process for this are the first steps to be taken in terms of a healthy adulthood.
  • Küçük Resim
    Öğe
    Laparoscopic versus open portoenterostomy for treatment of biliary atresia: a meta-analysis
    (Springer Science and Business Media, 2023) Okur, Mehmet Hanifi; Aydoǧdu, Bahattin; Azizoǧlu, Mustafa; Bilici, Salim; Bayram, Salih; Salık, Fikret
    Objective: Our goal was to compare laparoscopic portoenterostomy versus open portoenterostomy for the treatment of biliary atresia. Materials and methods: Using the databases EMBASE, PubMed, and Cochrane, we carried out a thorough literature search up to 2022. Studies comparing laparoscopic and open surgery for the treatment of biliary atresia were included. Results: Twenty-three studies comparing laparoscopic portoenterostomy (LPE) (n = 689) and open portoenterostomy (OPE) (n = 818) were considered appropriate for meta-analysis. Age at surgery time was lower in the LPE group than OPE group (I2 = 84%), (WMD − 4.70, 95% CI − 9.14 to − 0.26; P = 0.04). Significantly decreased blood loss (I2 = 94%), (WMD − 17.85, 95% CI − 23.67 to − 12.02; P < 0.00001) and time to feed were found in the laparoscopic group (I2 = 97%), (WMD − 2.88, 95% CI − 4.71 to − 1.04; P = 0.002). Significantly decreased operative time was found in the open group (I2 = 85%), (WMD 32.52, 95% CI 15.65–49.39; P = 0.0002). Weight, transfusion rate, overall complication rate, cholangitis, time to drain removal, length of stay, jaundice clearance, and two-year transplant-free survival were not significantly different across the groups. Conclusions: Laparoscopic portoenterostomy provides advantages regarding operative bleeding and the time to begin feeding. No differences in remain characteristics. Based on the data presented to us by this meta-analysis, LPE is not superior to OPE in terms of overall results.
  • Küçük Resim
    Öğe
    Letter to the editor for comparison between two minimally invasive techniques for Hirschsprung disease: transanal endorectal pull?through (TERPT) versus laparoscopic?TERPT
    (Springer Science and Business Media Deutschland GmbH, 2023) Azizoǧlu, Mustafa; Okur, Mehmet Hanifi
    We have read with interest the article “Comparison between two minimally invasive techniques for Hirschsprung disease: transanal endorectal pull-through (TERPT) versus laparoscopic-TERPT” (study period 2007–2017) published by Cantone et al.
  • Küçük Resim
    Öğe
    Protective effects of Silymarin on testicular torsion/detorsion in rats
    (2023) Azizoǧlu, Mustafa; Arslan, Serkan; Özkorkmaz, Ebru Gökalp; Aşır, Fırat; Basuguy, Erol; Okur, Mehmet Hanifi; Aydoğdu, Bahattin; Karabel, M. Alagöz; Kaplan, İbrahim
    OBJECTIVE: The present research aimed to study the possible protective effects of Silymarin on testicular I/R injury in a rat model evaluated through histopathology and biochemical parameters. MATERIALS AND METHODS: This research investigated the impact of Silymarin on IR damage in male Wistar albino rats. Animals were divided into three groups: group 1 (sham), group 2 (IR), and group 3 (IR+Silymarin). RESULTS: There were no notable differences in the levels of malondialdehyde (MDA), myeloperoxidase (MPO), and glutathione (GSH) across the three groups (p=0.260, p=0.486 and p=0.803, respectively). Contrarily, the total antioxidant status (TAS) levels exhibited significant variations between groups (p=0.001). The total oxidant status (TOS) levels also differed significantly between groups (p=0.004). The tissue evaluations uncovered substantial differences in the Johnson score, which is used to gauge testicular damage. A distinct contrast was seen between Group 1 and Group 2, and also between Group 2 and Group 3, with an all-encompassing p-value lower than 0.01. The same significant disparities were found for the percentages of Bax and Annexin V immunostaining (p<0.01 for each), reflecting the inflammation and apoptosis brought about by ischemia-reperfusion and the protective effects of the treatment. CONCLUSIONS: The outcomes of the current investigation showed that Silymarin could be a valuable agent for reducing testicular tissue damage following I/R injury.