Yazar "Aydin, M." seçeneğine göre listele

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    Association between the neutrophil to lymphocyte ratio and prehypertension
    (Aepress Sro, 2015) Aydin, M.; Yuksel, M.; Yildiz, A.; Polat, N.; Bilik, M. Z.; Akil, M. A.; Acet, H.
    OBJECTIVES: To explore the neutrophil-lymphocyte ratio (NLR) in patients with prehypertension (PHT). BACKGROUND: Inflammation plays an important role in the development of cardiovascular diseases. A pathophysiological link also exists between inflammation and PHT. NLR is a simple marker for the assessment of inflammatory status. There is a lack of data regarding the association between NLR and pre-hypertensive state. METHODS: The present cross-sectional study included 33 newly diagnosed PHT patients and 35 normotensive control subjects. Prehypertension was defined as a systolic blood pressure (BP) of 120-139 mm Hg and/or a diastolic BP of 80-89 mm Hg. RESULTS: Patients were divided into tertiles based on NLR values: 1.17 (0.9-1.42) in tertile 1; 1.57 (1.43-1.78) in tertile 2; and 2.40 (1.82-4.5) in tertile 3. The frequency of PHT was significantly higher for patients in the upper NLR tertile compared to the middle and lower NLR tertiles (21 (91.3 %), 7 (30.4 %), and 5 (22.7 %), respectively; p<0.001). Systolic BP and diastolic BP were significantly higher among patients in the upper NLR tertile than among those in the other NLR tertiles. CONCLUSION: An association exists between PHT and NLR. NLR measurement, as well as monocyte count, may be used to indicate increased risk of prehypertension (Tab. 2, Ref. 48). Text in PDF www.elis.sk.
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    The Association of Inteleukin (IL)-17 and IL-23 with rheumatic mitral stenosis
    (Oxford Univ Press, 2016) Bilik, M. Z.; Polat, N.; Kaplan, I.; Akil, M. A.; Halit, A.; Yuksel, M.; Aydin, M.
    [Abstract Not Available]
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    Electron paramagnetic resonance of ?-irradiated glycyl-L-glutamine monohydrate, iminodiacetic acid and methyliminodiacetic acid
    (Taylor & Francis Ltd, 2008) Aydin, M.; Osmanoglu, Y. E.; Baskan, M. H.
    The electron paramagnetic resonances of gamma-irradiated powders of glycyl- L- glutamine monohydrate, iminodiacetic acid and methyliminodiacetic acid were investigated at room temperature. The observed species in glycyl- L- glutamine monohydrate powders were attributed to the CH2<(C)over dot>NHCOOH radical; and those in iminodiacetic acid and methyliminodiacetic acid powders to the HN<(C)over dot>HCH2(COOH)(2) and H3CN<(C)over dot>HCH2(COOH)(2) radicals respectively. The spectra were computer simulated and the g values of the radicals and the hyperfine structure constants of the unpaired electron with nearby protons and N-14 nucleus were determined. The results were found to be in good agreement with the existing literature data.
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    EPICARDIAL ADIPOSE TISSUE THICKNESS IS ASSOCIATED WITH FREQUENT VENTRICULAR PREMATURE BEATS
    (Elsevier Ireland Ltd, 2013) Kiris, A.; Turan, O. E.; Kiris, G.; Ilter, A.; Ozturk, M.; Aydin, M.; Kaplan, S.
    [Abstract Not Available]
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    EPR STUDY OF FREE RADICALS IN AMINO ACIDS DERIVATIVES IRRADIATED BY GAMMA RAYS
    (Editura Acad Romane, 2011) Aydin, M.; Osmanoglu, Y. Emre
    Exposure of powders forms of DL-arginine hydrochloride and glycine hydrochloride to gamma radiation results in the formation of free radicals detected by electron paramagnetic resonance spectroscopy at room temperature. The observed radicals were assigned to be NH2(NH)NHCHCH2CH2CH(NH2)COOH and (NH3+) CHCOO- respectively. The g values and the hyperfine coupling constants of the unpaired electron with the environmental protons and N-14 nucleus were determined for these two radicals. These results were compared with the earlier studies on amino acid derivatives.
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    The impact of metabolic syndrome on carotid intima media thickness
    (Verduci Publisher, 2013) Aydin, M.; Bulur, S.; Alemdar, R.; Yalcin, S.; Turker, Y.; Basar, C.; Aslantas, Y.
    OBJECTIVES: Metabolic syndrome (MetS) is a cluster of metabolic abnormalities involving several cardiovascular risk factors. Carotid intima media thickness (CIMT) is an important early screening tool to assess subclinical manifestation of cardiovascular and metabolic diseases. We aimed to investigate the impact of MetS on CIMT in a large scaled community based study. METHODS: The study was conducted on 2102 participants. Carotid intima media thickness was measured in all of the participants. The study sample was divided into 4 groups; Group 1 subjects with a body mass index (BMI) < 25.0 kg/m(2) [n = 499 (MetS- = 488, MetS+ = 11)], Group 2 BMI between 25.0 and 29.9 kg/m(2) [n = 693 (MetS-= 559, MetS+ = 134)], Group 3 BMI between >= 30 kg/m(2) and 39.9 kg/m(2) [n = 822 (MetS-= 375, MetS+ = 477)], and Group 4 BMI >= 40 kg/m(2) [n = 88 (MetS-= 27, MetS+ = 61)]. RESULTS: Carotid intima media thickness was higher in the individuals with MetS compared to their normal counterparts. Furthermore, the sub-group analysis showed that CIMT values in Group 1 (0.55 +/- 0.18 vs 0.82 +/- 0.70; p < 0.001), Group 2 (0.59 +/- 0.20 vs 0.68 +/- 0.18; p < 0.001) and Group 3 (0.61 +/- 0.15 vs 0.65 +/- 0.18; p < 0.001) were significantly higher in subjects with MetS compared to their normal counterparts, whereas the values were similar in Group 4 (0.62 +/- 0.13 vs 0.65 +/- 0.17; p = 0.363). CONCLUSIONS: Carotid intima media thickness of overweight, obese and normal weight individuals without MetS were lower than their counterparts with MetS. MetS had no impact on CIMT in morbid obese individuals possibly due to established insulin resistance earlier than MetS.
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    Predictors of hypertension control in Turkey: the MELEN study
    (Verduci Publisher, 2013) Baltaci, D.; Erbilen, E.; Turker, Y.; Alemdar, R.; Aydin, M.; Kaya, A.; Celer, A.
    BACKGROUND: Hypertension is one of the most common causes of atherosclerosis, morbidity and mortality in adults. A total of 11 million hypertensive patients were estimated in Turkey. AIM: The aim of this study was to investigate the prevalence, awareness and control of hypertension in Duzce and compare the current data with the literature. PATIENTS AND METHODS: The visits were carried out in May and June, 2010 in Yigilca town health centre on 2298 participants (1471 female, 827 male with a mean age of 50). Data were obtained by a simple form, physical examination and sampling of blood. Hypertension was defined as a blood pressure 140 mmHg and/or 90 mmHg, and/or use of antihypertensive medication. The data of patients under control were compared with the patients who were not under control. RESULTS: Hypertension was detected in 964 participants. General prevalence was 42%. Hypertension awareness ratio was 70%, use of antihypertensive medication was 39% and the ratio of patients under control was 28%. Antihypertensive drug use, age and awareness were lower in the uncontrolled group. Logistic regression analysis revealed that only antihypertensive drug use and BMI < 30 were the independent predictors of hypertension under control [Odd's ratio (OR) = 3.43; 95% confidence interval (CI) = 2.54-4.64, p < 0.001 and OR = 1.69; 95% CI = 1.23-2.32, p = 0.01; respectively]. CONCLUSIONS: Hypertension is one of the most important public health problems in Turkey. According to the literature data the awareness of hypertension was increased significantly in the last five years. On the other hand, control ratio was increased very little compared with the previous studies.
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    The predictors of poor outcomes in patients with femoral artery injuries
    (Verduci Publisher, 2013) Yavuz, C.; Demirtas, S.; Caliskan, A.; Ertas, F.; Kaya, H.; Aydin, M.; Benli, E. D.
    PURPOSE: This study investigated the predictors of poor outcomes, including limb loss and death, in patients with femoral artery injuries. PATIENTS AND METHODS: The study included 158 patients aged 2-82 (mean age 28.4 +/- 16.5) with femoral arterial injury (common, deep, and superficial femoral artery) that were treated surgically between 2000 and 2010. Isolated venous injuries were excluded. Demographic and clinical data of the patients, including age, gender, admission time, pulse rate and blood pressure, hematocrit value, reason of injury, associated injury, and Mangled Extremity Severity Score (MESS) were recorded. RESULTS: Of the 158 patients, the death and amputation rates were 5.7% (9) and 5.1% (8), respectively. In logistic regression analysis, four variables (pulse rate, MESS, hematocrit, and bone trauma) were found to be independent predictors for poor outcomes. The Odd's ratios and confidence interval values of these variables were as follows: 7.24 (1.94-26.92), 21.75 (5.4187.48), 5.93 (3.04-11.54) and 7.46 (2.09-9.56), respectively. CONCLUSIONS: The MESS value, presence of bone fracture, hematocrit, and pulse rate on admission are predictive risk factors for poor outcomes in patients with femoral artery injury. Therefore, in these patients, prompt intervention by experienced surgeons is crucial for limb salvage and decreased mortality.
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    Radiation effect studies in single crystal of Trifluoroacetyl-?-Aminoisobutyric acid
    (Taylor & Francis Ltd, 2015) Baskan, M. Halim; Osmanoglu, Y. Emre; Sutcu, K.; Aydin, M.; Osmanoglu, S.
    In this study, electron paramagnetic resonance of -irradiated single crystals of N-Trifluoroacetyl--amino isobutyric acid (F3Ac-Aib-OH) was investigated at room temperature and analyzed for different orientations of the crystal in the magnetic field. The paramagnetic species in N-Trifluoroacetyl--aminoisobutyric acid was attributed to the CF2-R radical (R= CONHC(CH3)COOH). Hyperfine coupling constants and g value were also determined. In addition, the single crystal of F3Ac-Aib-OH was UV-irradiated and paramagnetic species formed was studied at room temperature. The effects of gamma irradiation on fluoroamino acid and stability were discussed.