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Öğe Bioelectrical impedance analyses of patients with postmenopausal osteoporosis(Ios Press, 2008) Sert, Cemil; Altindag, Ozlem; Dasdag, Sueleyman; Akdag, M. ZulkufBody composition undergoes changes with aging and menopause. This study was planned to investigate the body composition in postmenopausal women. Total lean, fat mass and total body BMD were measured by dual-energy X-ray absorptiometry (DXA). All subjects with a T-score less than - 1.5 were called the patient group. Total lean, fat mass and other components of body composition were also assessed by bioelectrical impedance (BIA). Demographical and physical characteristics were recorded for each subject. Total lean mass was significantly lower and fat mass was higher in the patient group than in healthy controls ( p < 0.05). BMD values were positively correlated with lean mass ( r = 0.336, p < 0.05). There were no significant differences between patients and healthy controls with regard to body composition measured by DXA and BIA ( p < 0.05). These findings suggest that there is a difference between postmenopausal women with osteopenia/osteoporosis and healthy controls with regard to fat and lean mass. Total lean mass may be an important determinant of BMD in postmenopausal women. BIA might be an alternative method to DXA for the measurement of total body fat and lean mass.Öğe Expert opinion and key recommendations for the physical therapy and rehabilitation of patients with ankylosing spondylitis(Wiley, 2012) Ozgocmen, Salih; Akgul, Ozgur; Altay, Zuhal; Altindag, Ozlem; Baysal, Ozlem; Calis, Mustafa; Capkin, ErhanAim: Physiotherapy is an integral part of the management of ankylosing spondylitis (AS) and there is a need for recommendations which focus on the rehabilitation of patients with AS. We aimed to develop recommendations for the physical therapy and rehabilitation of patients with AS based on the evidence and expertise. Methods: The Anatolian Group for the Assessment in Rheumatic Diseases (ANGARD) is a scientific group of Turkish academicians (physiatrists and rheumatologists) who are experts in the rehabilitation of patients with AS. A systematic literature search summarizing the current available physiotherapy and rehabilitation trials in AS were presented to the experts before a special 2-day meeting. Experts attending this meeting first defined a framework based on the main principles and thereafter collectively constructed six major recommendations on physiotherapy and rehabilitation in AS. After the meeting an email survey was conducted to rate the strength of the recommendations. Results: Six key recommendations which cover the general principles of rehabilitation in AS in terms of early intervention, initial and follow-up assessments and monitoring, contraindications and precautions, key advice for physiotherapy methods and exercise were constructed. Conclusion: These recommendations were developed using evidence-based data and expert opinion. The implementation of these recommendations should encourage a more comprehensive and methodical approach in the rehabilitation of patients with AS. Regular lifelong exercise is the mainstay of rehabilitation and there is a considerable need for well-designed studies which will enlighten the role of physical therapy in the management of AS.Öğe Paraoxonase and arylesterase activities in fibromyalgia(Taylor & Francis Ltd, 2007) Altindag, Ozlem; Gur, Ali; Calgan, Nazife; Soran, Neslihan; Celik, Hakim; Selek, SahabettinPublished by Maney Publishing ( c) W. S. Maney & Son Limited We aimed to evaluate the association of serum paraoxonase and arylesterase activities and oxidative/ antioxidative status in patients with fibromyalgia. Forty-two patients with fibromyalgia and 53 healthy controls were included in the study. Serum paraoxonase and arylesterase activities were measured spectrophotometrically. Oxidative and antioxidative status were evaluated by measuring serum lipid hydroperoxide ( LOOH) levels, total antioxidant status ( TAS) and free sulfhydryl groups ( - SH = total thiol). Lipid parameters were determined by routine laboratory methods. Serum paraoxonase and arylesterase activities, and TAS were lower in patients with fibromyalgia than in controls ( P < 0.001, for all), and the - SH level was also lower in the patient group ( P = 0.03). LOOH levels were higher in the patient group than in controls ( P = 0.01). Our results suggest that patients with fibromyalgia were exposed to oxidative stress, and paraoxonase and arylesterase activities were decreased in these patients. Patients with fibromyalgia might be prone to development of atherosclerosis with reduced paraoxonase and arylesterase activities.Öğe The relationship between clinical parameters and depression level in patients with myofascial pain syndrome(Oxford Univ Press, 2008) Altindag, Ozlem; Gur, Ali; Altindag, AbdurrahmanObjective. Several studies and reviews have documented the high degree of comorbidity between depression and chronic pain. It was reported that chronic muscle pain is frequently accompanied by symptoms of depression. The purpose of this study was then to investigate the prevalence of major depression in chronic pain patients (CPP) with myofascial pain syndrome (MPS) and to investigate the relationship between some clinical parameters and level of depression, utilizing a healthy control group without MPS. Design/Setting/Patients. The study group consisted of 77 MPS patients (65 female, 12 male) and 72 healthy volunteers (60 female, 12 male). The diagnosis of MPS was based on clinical characteristics, examination findings, and ruling out other diagnoses. Major depressive disorder was diagnosed by a psychiatrist utilizing DSM-IV criteria. Levels of depression were obtained from the Beck Depression Inventory (BDI). Results. There was no significant difference between MPS patients and controls with respect to age and gender (P > 0.05). The mean age of the patients was 31.1 years (SD 9.8) and the mean age of controls was 29.7 years (SD 7.1). Major depression was more frequently found in CPPs with MPS (P < 0.001). BDI scores were higher in the MPS group than in controls (P < 0.001). There was a significant correlation between the severity of pain and depression level in patients with MPS (r = 0.654, P < 0.001). Conclusion. Major depression is found in MPS CPPs at a rate previously noted in the literature in mixed diagnoses CPPs. In addition, the severity of the depression may be related to perceived pain severity.
