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Öğe Acute thrombus formation on an Occlutech ASD Occluder device during transcatheter closure: Case report(Ortadoğu Reklam Tanıtım Yayıncılık, 2016) Bilik, Mehmet Zihni; Akıl, Mehmet Ata; Acet, Halit; Kaya, Hasan; Ertaş, FarukAcute thrombosis during transcatheter device closure of atrial septal defect is a very rare but important complication. A 67-year-old woman with secundum type atrial septal defect underwent closure with the Occlutech Figula device. Acetilsalicylic acid and clopidogrel had been started one day before procedure and heparin was given at the beginning of the procedure. During the intervention a thrombus on the left atrial disk was detected by transesophageal echocardiography (TEE). The delivery system and thrombus were succesfully removed from circulation. Additional heparin bolus was given and the procedure was completed succesfully. The control TEE showed good device position and no thrombus formation on the device. The patient was discharged without any complication.Öğe Apelin Levels In Isolated Coronary Artery Ectasia(Korean Soc Cardiology, 2015) Bilik, Mehmet Zihni; Kaplan, Ibrahim; Yildiz, Abdulkadir; Akil, Mehmet Ata; Acet, Halit; Yuksel, Murat; Polat, NihatBackground and Objectives: The etiopathogenesis of coronary artery ectasia (CAE) is not known completely. In most of the cases, CAE is associated with atherosclerosis; however, isolated CAE has a nonatherosclerotic mechanism. The association between atherosclerotic coronary artery disease and apelin has been examined in previous studies. However, the role of plasma apelin in isolated coronary artery ectasia has not been studied. In this study, we investigated the relationship between plasma apelin levels and isolated coronary artery ectasia. Subjects and Methods: The study population included a total of 54 patients. Twenty-six patients had isolated CAE (53.6 +/- 8.1 years); 28 patients with normal coronary arteries (51.6 +/- 8.8 years) and with similar risk factors and demographic characteristics served as the control group. Apelin levels were measured using an enzyme-linked immunoassay kit. Results: Apelin level in the CAE group was significantly lower (apelin=0.181 +/- 0.159 ng/mL) than that in the control group (apelin=0.646 +/- 0.578 ng/mL) (p=0.033). Glucose, creatinine, total cholesterol, triglyceride, low density lipoprotein cholesterol, and high density lipoprotein cholesterol levels were not significantly different between the two groups. Conclusion: In this study, we showed that patients with isolated CAE have decreased plasma apelin levels compared with the control group. Based on the data, a relationship between plasma apelin and isolated CAE was determined.Öğe Assessment of atrial electromechanical delay and P-Wave dispersion in patients with Psoriasis(Echocardiography- A Journal Cardiovascular Ultrasound and Allied Techniques, 2014) Yildiz, Abdulkadir; Ucmak, Derya; Oylumlu, Mustafa; Akkurt, Meltem Z.; Yuksel, Murat; Akil, Mehmet Ata; Polat, Nihat; Aydin, Mesut; Bilik, M. Zihni; Acet, HalitBackground: In this study, we sought to evaluate atrial electromechanical properties and conduction homogeneity by tissue Doppler imaging and electrocardiography in patients with psoriasis. Methods: Thirty-four patients with psoriasis and 30 age-and gender-matched healthy controls were included in the study. Atrial electromechanical coupling intervals were assessed by means of tissue Doppler echocardiography and P-wave dispersion (Pd) was calculated from electrocardiogram. Results: A total of 64 subjects (33 male) with a mean age of 36.8 +/- 11.9 years were included in the study. Basal characteristics were similar between 2 groups. Intra-atrial (15 +/- 7 ms vs. 12 +/- 5 ms, P = 0.009) and inter-atrial (28 +/- 7 ms vs. 23 +/- 7 ms, P = 0.002) electromechanical delays were significantly higher in patients with psoriasis compared with control groups. P-maximum (112 +/- 16 ms vs. 103 +/- 8 ms, P = 0.006) and Pd (35 +/- 9 ms vs. 20 +/- 6 ms, P < 0.001) were also prolonged in patients with psoriasis. Conclusion: This study demonstrated that atrial electromechanical coupling intervals and P-wave dispersion were prolonged in patients with psoriasis, which may cause an increased risk of atrial fibrillation in this patient group.Öğe Assessment of Platelet to Lymphocyte Ratio to Predict Stent Thrombosis in Patients with ST Elevation Myocardial Infarction(Elsevier Science Inc, 2013) Yildiz, Abdulkadir; Yuksel, Murat; Oylumlu, Mustafa; Bilik, Mehmet Zihni; Acet, Halit; Akil, Mehmet Ata; Polat, Nihat[Abstract Not Available]Öğe The association between coronary slow flow and platelet distribution width among patients with stable angina pectoris(Termedia Publishing House Ltd, 2014) Ozyurtlu, Ferhat; Yavuz, Veysel; Cetin, Nurullah; Acet, Halit; Ayhan, Erkan; Isik, TurgayIntroduction: Coronary slow flow (CSF) is an angiographic phenomenon characterised by the delay of distal vessel opacification in the absence of significant stenosis of the epicardial coronary arteries. Some of the factors playing a role in CSF pathophysiology are increased thrombogenic activity and inflammation. Aim: To examine the relationship between platelet distribution width (PDW) and CSF. Material and methods: Taking into consideration the exclusion criteria, 136 patients with CSF and 152 patients with normal coronary angiographies (control group) were included in the study. The association between thrombolysis infarction frame count (TFC) in myocardial and laboratory and other clinical parameters were evaluated. Results: The stated parameters were significantly higher in the group with CSF than in the normal coronary angiography group (control group). The PDW (16.6 +/- 0.7 vs. 16.4 +/- 0.6, p = 0.002), neutrophil lymphocyte ratio (NLR) (3.1 +/- 3.4 vs. 2.4 +/- 1.1, p = 0.027), haemoglobin (Hb) (14.1 +/- 1.3 vs. 14.7 +/- 1.1, p < 0.001), and red cell distribution width (Row) (13.6 +/- 0.7 vs. 14.1 +/- 2.8, p = 0.026) were significantly higher in the CSF group than in the control group. Moreover, our study showed that PDW > 16.15 and Hb > 13.75 were predictors of the presence of CSF with sensitivities of 83% and 73% and specificities of 40% and 42%, respectively. Conclusions: This study has demonstrated that compared to normal coronary flow, PDW, Hb, NLR, and RDW are significantly higher in CSF patients. We believe that further studies are needed to clarify the role of PDW and Hb in patients with CSF.Öğe The Association between Neutrophil to Lymphocyte Ratio and Presence of Ventricular Premature Contractions(Elsevier Science Inc, 2013) Yildiz, Abdulkadir; Yuksel, Murat; Oylumlu, Mustafa; Polat, Nihat; Acet, Halit; Bilik, Mehmet Zihni; Aydin, Mesut[Abstract Not Available]Öğe The association between platelet/lymphocyte ratio and coronary artery disease severity(Turkish Society of Cardiology, 2015) Yüksel, Murat; Yıldız, Abdulkadir; Oylumlu, Mustafa; Akyüz, Abdurrahman; Aydın, Mesut; Kaya, Hasan; Acet, Halit; Polat, Nihat; Bilik, Mehmet Zihni; Alan, SaitObjective: In this study, we aimed to explore the association between platelet-to-lymphocyte ratio (PLR) and the severity of atherosclerosis in coronary artery disease (CAD). Methods: Clinical and laboratory data of 388 patients who underwent coronary angiography were evaluated retrospectively. Gensini score, which indicates the severity of atherosclerosis, was calculated for all of the patients. Patients with CAD were categorized as mild and severe atherosclerosis, according to their Gensini score. Eighty patients with normal coronary arteries formed the control group. Mean PLR values of the three study groups were compared. Also, PLR value was tested for whether it showed a positive correlation with Gensini score. Results: The mean PLR of the severe atherosclerosis group was significantly higher than that of the mild atherosclerosis and controls groups (p<0.001). Also, PLR was positively correlated with Gensini score in CAD patients. A cut-off value of 111 for PLR predicted severe atherosclerosis with 61% sensitivity and 59% specificity. Pre-procedural PLR level was found to be independently associated with Gensini score, together with WBC, age, and low HDL level, in the multivariate analysis. Conclusion: Our study suggests that high PLR appears to be additive to conventional risk factors and commonly used biomarkers in predicting severe atherosclerosis. (Anatol J Cardiol 2015; 15: 640-7).Öğe The Association Between the Neutrophil-to-Lymphocyte Ratio and the Presence of Ventricular Premature Contractions in Young Adults(Sage Publications Inc, 2015) Yildiz, Abdulkadir; Oylumlu, Mustafa; Yuksel, Murat; Aydin, Mesut; Polat, Nihat; Acet, Halit; Akil, Mehmet AtaInflammation has recently emerged in the pathogenesis of several cardiovascular disorders, including arrhythmias. The neutrophil-lymphocyte ratio (NLR) is a simple marker for the assessment of inflammatory status. Therefore, we aimed to investigate the relationship between the NLR and the ventricular premature contraction (VPC) existence. Patients aged between 18 and 40 years who were referred to the cardiology clinic were enrolled in the study. All patients' complete blood counts and 24-hour Holter recordings were analyzed. The NLR was higher within the VPC group compared to the control group (P < .001). According to the NLR tertiles, VPCs were more common in the higher NLR tertile (P < .001). A cutoff point of 1.80 for the NLR had 71% sensitivity and 60% specificity in predicting VPC in apparently healthy individuals. After multivariate analysis, only the NLR remained significant predictor of presence of VPC. In conclusion, the NLR is independently and significantly associated with VPC existence.Öğe The association between the neutrophil/lymphocyte ratio and functional capacity in patients with idiopathic dilated cardiomyopathy(Turkish Soc Cardiology, 2015) Yildiz, Abdulkadir; Yuksel, Murat; Oylumlu, Mustafa; Polat, Nihat; Akil, Mehmet Ata; Acet, HalitObjective: The neutrophil/lymphocyte ratio (NLR) is an inexpensive, readily available and reliable inflammatory marker, which has a predictor value in different cardiovascular disorders. Functional capacity is one of the most important prognostic factors in patients with heart failure, which is usually stated as metabolic equivalents (MET). The goal of the study was to investigate the relationship between the NLR and functional capacity (FC) in patients with idiopathic dilated cardiomyopathy (IDC). Methods: Treadmill test according to modified-Bruce protocol was performed in 37 patients with IDC (mean age 46.7 +/- 11.7 years, 81.1% male) to assess their functional capacity. Baseline clinical and echocardiographic variables were obtained. Hematological and biochemical parameters were measured using standard techniques. Results: The patients were divided into low (<5 MET, n=18) and high (>5 MET, n=19) FC groups according to their functional status in the exercise test. The 2 groups were similar regarding age, gender and the presence of hypertension and diabetes mellitus. There was no significant difference between groups regarding echocardiographic parameters such as left ventricular ejection fraction and diameters. However, the NLR was significantly higher in low FC group compared to high FC group (3.62 +/- 2.24 vs. 2.24 +/- 0.67, p=0.002; respectively). There were significant negative correlations between the NLR, MET and left ventricular ejection fraction (r=-0.405, p=0.013 and r=-0.028, p=0.028; respectively). Diastolic dysfunction was present in all the patients with low functional capacity. A cut-off point of 2.26 for the NLR had 83% sensitivity and 69% specificity in predicting poor FC. After multivariate analysis, only the NLR remained significant predictor of poor functional status. Conclusion: We detected a significant association between the NLR and low FC, both of which has predictive and prognostic value in patients with heart failure. Functional capacity may depend on diastolic function rather than left ventricular ejection fraction in patients with IDC.Öğe Association of Neutrophil-Lymphocyte Ratio With the Presence and Severity of Rheumatic Mitral Valve Stenosis(Sage Publications Inc, 2014) Polat, Nihat; Yildiz, Abdulkadir; Yuksel, Murat; Bilik, Mehmet Zihni; Aydin, Mesut; Acet, Halit; Akil, Mehmet AtaThe aim of the study is to investigate the association between the severity of rheumatic mitral valvular disease (RMVD) and the neutrophil-lymphocyte ratio (NLR). A total of 227 patients were enrolled in the study and divided into 3 groups. Patients in group 1 had rheumatic mitral stenosis (RMS), those in group 2 had RMVD without stenosis, and those in group 3 served as the control group. Group 1 was further divided into 2 groups, severe mitral stenosis (MS) and mild to moderate MS. The NLR was significantly higher in patients with severe MS when compared to those with mild to moderate MS (P = .002) while lymphocyte count was lower (P = .034). Using a cutoff level of 2.56, the NLR predicted severe RMS with a sensitivity of 75% and specificity of 74%. In conclusion, as an inexpensive, simple, and accessible marker of inflammation, the NLR may be useful in predicting the presence and severity of MS in patients with RMVD.Öğe Atropine-induced non-sustained polymorphic ventricular tachycardia: A rare case(Modestum Ltd., 2014) Aydın, Mesut; Yıldız, Abdulkadir; Polat, Nihat; Acet, Halit; İslamoğlu, YahyaA 40 years old male with history of unexplained recurrent presyncope and palpitation episodes referred to cardiology department. Patient had no past medical history. Subsequently, electrophysiology study was performed to detect any underlying atrioventricular nodal disease or inducible tachyarrhythmias. During this period, 1.0 mg of atropine was injected intravenously to performed stimulation and patient suddenly developed polymorphic ventricular tachycardia that could not be terminated with overdrive pacing. Ventricular tachycardia was terminated spontaneously, two minutes later. J Clin Exp Invest 2014; 5 (3): 449-451.Öğe The clinical significance of anticardiolipin antibody levels in patients with acute myocardial infarction: a regional study(Termedia Publishing House Ltd, 2013) Ertas, Faruk; Can, Oznur; Acet, Halit; Ozbakkaloglu, MertIntroduction: Acute myocardial infarction (AMI) will probably remain the most important cause of death over the next decades. Traditional risk factors of atherosclerosis could not exactly explain the development of acute coronary events such as AMI. Antiphospholipid antibody syndrome is a disorder characterized by the development of arterial and venous thrombosis. Aim: In this study, we investigated the relations between acute myocardial infarction and anti-phospholipid antibody syndrome in our population representing Aegean Region people characteristics. Material and methods: One hundred patients with acute myocardial infarction were consecutively included in the study (group I) and one hundred age and sex matched people with similar risk factors were enrolled in the study as a control group (group II). Anticardiolipin antibody (aCL) IgM and IgG levels were measured in the two groups. Levels of aCL IgG >= 48 U/ml and/or aCL IgM >= 44 U/ml were accepted as positive and significant. Results: In patients with acute myocardial infarction, 5 patients (5%) had positive IgM levels and 8 patients (8%) were found to have positive IgG levels. All cases in the control group had negative aCL IgM and IgG antibody levels. These results were accepted as significant for both aCL antibodies between patients and controls (p < 0.001). Conclusions: We concluded that aCL antibody levels are also higher in a small proportion of patients with acute myocardial infarction than controls in our region, also, and these results suggest that there may be an immune stimulus in the pathogenesis of acute coronary events.Öğe A co-anomaly: hourglass-like aorta and giant coronary arteries(Turkish Soc Cardiology, 2014) Akil, Mehmet Ata; Bilik, Mehmet Zihni; Acet, Halit; Ertas, Faruk; Yildiz, Abdulkadir[Abstract Not Available]Öğe Dependence of clinical outcomes on time of hospital admission in patients with ST-segment elevation myocardial infarction(King Faisal Specialist Hospital and Research Centre, 2023) Özbek, Mehmet; Ildirimli, Kamran; Arık, Baran; Aktan, Adem; Coşkun, Mehmet Sait; Evsen, Ali; Güzel, Tuncay; Acet, Halit; Demira, MuhammedBACKGROUND: There are conflicting results in studies investigating the effects of percutaneous coronary intervention (PCI) on the prognosis of patients with ST-segment elevation myocardial infarction (STEMI) during or outside of usual hospital working hours. While some researchers have reported higher mortality rates in STEMI patients admitted outside of working hours, others did not find a statistically significant difference. OBJECTIVES: Investigate the short-term endpoints and long-term outcomes of STEMI patients by time of admission. DESIGN: Retrospective SETTING: Tertiary percutaneous coronary intervention center. PATIENTS AND METHODS: Patients were grouped by admission, which consisted of four intervals: 06:00 to <12:00, 12:00 to <18:00, 18:00 to <24:00, and 24:00 to <06:00. We analyzed demographic, clinical and mortality by admission time interval and mortality by multivariate analyses, including the time intervals. MAIN OUTCOME MEASURES: Clinical data and mortality SAMPLE SIZE: 735 patients; median (IQR) age 62 (22) years; 215 (29.3%) women. RESULTS: Patients admitted at night were 1.37 times more likely to experience pulmonary edema than patients whose symptoms started in the daytime (P=.012); 32.9% of the patients whose symptoms started at night presented with Killip class II-IV, while during the daytime, 21.4% presented with Killip class II-IV (P=.001). Among the patients, the most common was inferior STEMI (38.6%). However, no-reflow was significantly higher during the daytime compared to the nighttime (P=.12). The risk of the cardiac arrest on admission was 1.2 times higher in patients admitted at night (P=.034). Neither time interval of admission nor several other variables had an effect on clinical outcome or mortality. CONCLUSIONS: While patients admitted at night presented with pulmonary edema and cardiogenic shock more frequently, no reflow was observed during the day after the procedure. Although patients admitted at night with STEMI presented with worse clinical conditions, similar results were observed between the groups in clinical outcomes. LIMITATIONS: More “real world” results might have been obtained if the study had replicated more typical referral conditions for PCI. CONFLICT OF INTEREST: None.Öğe Dev disekan aort anevrizmasına bağlı Ortner sendromu(2013) Tasal, Abdurrahman; Bilik, Mehmet Zihni; Acet, Halit; Özyurtlu, FerhatÖzet– Ortner senromu kardiyovasküler nedenlerle olu şan sol larenjeal reküren sinir basısına bağlı ses kısık lığıdır. Kardiyovasküler nedenler kalp kapak hastalıkları, torasik aort anevrizması, doğuştan kalp hastalıkları gibi geniş bir yelpazeye sahiptir. Bu yazıda, literatürde daha önce bildirilmemiş büyüklükte bir çapa (120 mm) ulaşan dev disekan aort anevrizmasına bağlı olarak gelişen Ort ner sendromu olgusu sunuldu. Yetmiş bir yaşındaki erkek hasta efor dispnesi, halsizlik ve ses kısıklığı yakınmaları ile başvurdu. İndirekt laringoskopik bakıda sol ses teli felci görülen hastanın göğüs radyografisinde sol üst zonu dol duran 120 mm’ye ulaşan kitle saptandı. Toraksın bigisa yarlı tomografisinde aort yayı düzeyinde çapı 120 mm’ye ulaşan diseksiyon gelişmiş aort anevrizması vardı. Öneri len cerrahi tedaviyi kabul etmeyen hasta izlemin 4. ayında kaybedildi.Öğe Distribution of Accessory Pathways in Atrioventricular Reentrant Tachycardia in Southeast Anatolian Region of Turkey(Duzce Univ, 2015) Aydin, Mesut; Polat, Nihat; Yuksel, Murat; Yildiz, Abdulkadir; Acet, Halit; Bilik, Mehmet Zihni; Akil, Mehmet AtaObjective: We aimed to evaluate distribution of accessory pathway (AP) in atrioventricular reentrant tachycardia (AVRT) in southeast Anatolian region of Turkey. Methods: The study was a retrospective cross-sectional design. Consecutive patients who underwent catheter ablation of AVRT between June 2012 and July 2014 were included in the study. All patients were taken to the electrophysiology laboratory in the non-sedated state and underwent an initial diagnostic study using three diagnostic catheters. The one of them was placed in coronary sinus. In those patients, in whom the AP was identified, ablation therapy was carried out using radiofrequency energy. We decided distribution of AP on fluoroscopy. Fluoroscopic images are obtained in and the left anterior oblique orientation. Results: The study population consisted of 64 AVRT patients (63% female; mean age 34 +/- 14). Among AVRT 20(31%) patients had concealed AVRT, 44 (69%) patients had Wolf Parkinson White syndrome. Distribution of AP was 59% at the left free wall, 34% at the posteroseptum, 6% at the right free wall, and 3% at the anteroseptum. The locations of APs were compared. There was no any statistically significant among groups. Conclusion: Distribution of AP location was in accordance with literature. The other characteristic of AVRT were similar with the current data.Öğe Distribution of Accessory Pathways in Atrioventricular Reentrant Tachycardia in Southeast Anatolian Region of Turkey(2015) İslamoğlu, Yahya; Özaydoğdu, Necdet; Polat, Nihat; Akıl, Mehmet Ata; Aydın, Mesut; Aktan, Adem; Acet, HalitAmaç: Güneydoğu Anadolu bölgesinde atriyoventriküler reentran taşikardilerdeki (AVRT) aksesuar yolları değerlendirmeyi amaçladık. Yöntem: Çalışma retrospektif kesitsel olarak yapıldı. Haziran 2012- Temmuz 2014 tarihleri arasında ardışık olarak AVRT nedeniyle ablasyon tedavisi yapılan hastaları çalışmaya dahil ettik. Bütün hastalar elektrofizyoloji laboratuvarına sedasyon yapılmadan alındı. 3 diyagnostik kateter kullanılarak elektrofizyolojik çalışma yapıldı. Koroner sinüse diyagnostik kateter yerleştirildi. Aksesuar yol tespit edildiğinde radyofrekans enerji kullanılarak tedavi yapıldı. Aksesuar yolların lokalizasyonu floroskopik olarak sol ön oblik pozisyonda belirlendi. Bulgular: Çalışmaya 64 AVRTli hasta dahil edildi (%63 kadın, yaş ortalaması 34±14). Atriyoventriküler reentran taşikardili hastaların 20 (%31)si gizli AVRT, 44 (%63)ü WPW sendromu olduğu saptandı. Aksesuar yolların bulunduğu yerlerin sol serbest duvar %59, posteroseptum %34, sağ serbest duvar %6 ve anteroseptum %3 olarak saptadık. Aksesuar yollar karşılaştırıldı. Gruplar arasında istatistiksel olarak herhangi bir fark yoktu. Sonuç: Aksesuar yolların bulunduğu bölgelerin dağılımı literatür ile benzer bulundu. Atriyoventriküler reentran taşikardiler arasında herhangi bir fark olmadığını belirlendi.Öğe An epidemiological study to evaluate the use of vitamin K antagonists and new oral anticoagulants among non-valvular atrial fibrillation patients in Turkey- AFTER*-2 study design(Türk Kardiyoloji Derneği, 2015) Ertaş, Faruk; Kaya, Hasan; Yıldız, Abdulkadir; Davutoğlu, Vedat; Kiriş, Abdulkadir; Dinç, Lale; Kafes, Habibe; Avcı, Anıl; Çalapkorur, Bekir; Ertaş, Gökhan; Gül, Mehmet; Ay, Nuray Kahraman; Bulur, Serkan; Durukan, Mine; Eren, Murat; İlhan, İbrahim; Küçük, Murathan; Özpelit, Ebru; Şimşek, Hakkı; Uçar, F. Mehmet; Yıldız, Ahmet; Şahin, Yıldıray; Ayhan, Erkan; Çağlayan, Emre; Güngör, Hasan; Özyurtlu, Ferhat; Şen, Nihat; Vatan, Bülent; Vatansever, Fahriye; Kobat, Mehmet Ali; Temiz, Ahmet; Taylan, Gökay; Dönmez, İbrahim; Erkuş, M. Emre; Söylemez, Selami; Zengin, Halit; Gündüz, Mahmut; Tuncez, Abdullah; Karavelioğlu, Yusuf; Gökdeniz, Tayyar; Koza, Yavuzer; Aktop, Ziyaeddin; Katlandur, Hüseyin; Özer, Pelin Karaca; Yüksel, Murat; Acet, Halit; Çil, Habib; Alan, Sait; Toprak, NizamettinObjectives: Atrial fibrillation (AF) is one of the most common causes of preventable ischemic stroke and is related to increased cardiovascular morbidity and mortality. There is a lack of data in Turkey on the use of new oral anticoagulants (NOACs), and time in therapeutic INR range (TTR) in vitamin K antagonist users and AF management modality. In this multi-center trial, we aimed to analyze, follow and evaluate the epidemiological data in non-valvular AF patients. Study design: Four thousand one hundred consecutive adult patients from 42 centers with at least one AF attack identified on electrocardiography will be included in the study. Patients with rheumatic mitral valve stenosis and prosthetic valve disease will be excluded from the study. At the end of one year, the patients will be evaluated in terms of major cardiac end points (death, transient ischemic attack, stroke, systemic thromboembolism, major bleeding and hospitalization). Results: First results are expected in June 2015. Data about major cardiovascular end-points will be available in January 2016. Conclusion: The rates and kind of oral anticoagulant use, TTR in vitamin K antagonist users and main management modality applied in non-valvular AF patients will be determined by AFTER-2 study. In addition, the rate of major adverse events (MACEs) and the independent predictors of these MACEs will be detected (AFTER-2 Study ClinicalTrials.gov number, NCT02354456.).Öğe Evaluation of fluid status related parameters in hemodialysis and peritoneal dialysis patients: Clinical usefulness of bioimpedance analysis(Elsevier Urban & Partner Sp. Z O O, 2014) Yilmaz, Zulfukar; Yildirim, Yasar; Aydin, Fatma Yilmaz; Aydin, Emre; Kadiroglu, Ali Kemal; Yilmaz, Mehmet Emin; Acet, HalitBackground and objective: Fluid overload is a common and serious problem that leads to severe complications in dialysis patients. We aimed to compare hydration status as measured with bioimpedance analysis (BIA) method in hemodialysis (HD) and peritoneal dialysis (PD) patients, as well as investigating the association between blood pressure, left ventricular mass index (LVMI) and hydration status. Materials and methods: We examined 43 HD and 33 PD patients. Blood pressure was recorded. In each group, echocardiographic examinations were performed on all patients. Hydration status was assessed using multifrequency bioelectrical impedance analysis. Overhydration was defined as an overhydration (OH)/extracellular water (ECW) ratio of >0.15. Results: The OH/ECW ratio was significantly higher in PD patients compared to post-HD patients. Overhydration was statistically more frequent in PD than in post-HD patients (30.3% vs. 11.6%, P = 0.043). Systolic blood pressure (SBP) in both post-HD and PD groups, and LVMI in the PD group were found to be significantly higher in overhydrated patients than non-overhydrated patients. In multiple linear regression analyses, increased OH/ECW ratio was independently associated with higher SBP and LVMI. Conclusions: Fluid overload may be an even more prevalent and serious problem in PD patients. Overhydration is closely associated with increased blood pressure and LVMI. OH/ECW ratio, a derived parameter of fluid load measured by BIA, was a significant and independent determinant of SBP and LVMI. (C) 2014 Lithuanian University of Health Sciences. Production and hosting by Elsevier Urban & Partner Sp. z o.o. All rights reserved.Öğe Evaluation of Platelet to Lymphocyte Ratio to Predict No-Reflow in Patients With Acute Myocardial Infarction(Elsevier Science Inc, 2013) Yildiz, Abdulkadir; Tuncez, Abdullah; Polat, Nihat; Acet, Halit; Oylumlu, Mustafa; Yuksel, Murat; Akyuz, Abdurrahman[Abstract Not Available]
