Browsing by Author "Varisli, Lokman"

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Dissecting pharmacological effects of chloroquine in cancer treatment: interference with inflammatory signaling pathways

Varisli, Lokman; Cen, Osman; Vlahopoulos, Spiros (IMMUA, 2020)

Chloroquines are 4-aminoquinoline-based drugs mainly used to treat malaria. At pharmacological concentrations, they have significant effects on tissue homeostasis, targeting diverse signaling pathways in mammalian cells. ...
Increased ROS alters E-/N-cadherin levels and promotes migration in prostate cancer cells

Varisli, Lokman; Tolan, Veysel (Aepress, 2022)

Background: Increased ROS has been reported to cause a change in E- and N-cadherin levels, and consequently promotes migrative behaviors in pancreas and breast cancer cells. In this study, the effect of a sublethal dose ...