Browsing by Author "Toprak, Gulten"
Now showing items 1-11 of 11
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Cytoprotective effects of amifostine, ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats
Akbulut, Sami; Elbe, Hulya; Eris, Cengiz; Dogan, Zumrut; Toprak, Gulten; Otan, Emrah; Erdemli, Erman (Baishideng Publishing Group Inc, 2014)AIM: To investigate the potential role of oxidative stress and the possible therapeutic effects of N-acetyl cysteine (NAC), amifostine (AMF) and ascorbic acid (ASC) in methotrexate (MTX)-induced hepatotoxicity. METHODS: ... -
Determination of dermatology life quality index, and serum C-reactive protein and plasma interleukin-6 levels in patients with chronic urticaria
Ucmak, Derya; Akkurt, Meltem; Toprak, Gulten; Yesilova, Yavuz; Turan, Enver; Yildiz, Ismail (Termedia Publishing House Ltd, 2013)Introduction: C-reactive protein (CRP) and interleukin-6 (IL-6), which is one of its most important simulators, were determined in great amounts in the sera of patients with chronic urticaria (CU). Aim: To determine the ... -
Effects of antioxidant agents against cyclosporine-induced hepatotoxicity
Akbulut, Sami; Elbe, Hulya; Eris, Cengiz; Dogan, Zumrut; Toprak, Gulten; Yalcin, Erhan; Otan, Emrah (Academic Press Inc Elsevier Science, 2015)Background: To investigate the potential protective antioxidant role of ursodeoxycholic acid (UDCA), melatonin, and allopurinol treatment in cyclosporine (CsA)-induced hepatotoxicity. Methods: Hepatotoxicity was established ... -
Effects of Storage Temperature and Time on Stability of Serum Tacrolimus and Cyclosporine A Levels in Whole Blood by LC-MS/MS
Kaplan, Ibrahim; Yuksel, Hatice; Evliyaoglu, Osman; Basarali, M. Kemal; Toprak, Gulten; Colpan, Leyla; Sen, Velat (Hindawi Ltd, 2015)Tacrolimus and cyclosporine A are immunosuppressant drugs with narrow therapeutic windows. The aim of this study was to investigate the stability of tacrolimus and cyclosporin A levels in whole blood samples under different ... -
Effects of Sublethal Doses of Thiacloprid, a Neonicotinoid Insecticide, on Learning and Memory Performance of Mice
Akkoc, Hasan; Acar, Abdullah; Toprak, Gulten; Uyar, Emre (Asian Network Scientific Information-Ansinet, 2020)Background and Objective: Thiacloprid (THI), a neonicotinoid insecticide, currently one of the most preferred insecticides worldwide. Although they are claimed to be less hazardous on mammals, late studies revealed the ... -
Evaluation of testosterone levels in men with metabolic syndrome
Iltumur, Kenan; Karabulut, Aziz; Toprak, Gulten; Yokus, Beran; Toprak, Nizamettin (Turkish Soc Cardiology, 2005)Objectives: Low plasma levels of testosterone in men are associated with increased risk for atherosclerosis. In this study, we assessed plasma testosterone levels in patients with metabolic syndrome (MS) and its relationship ... -
Investigating the Effects of Trolox on Behaviour and Biochemical Parameters in Mice Exposed to Immobilization Stress
Toprak, Gulten; Akkoc, Hasan; Uyar, Emre (Asian Network Scientific Information-Ansinet, 2019)Background and Objective: Stress is known to play a causal role in several neuropsychiatric disorders. Trolox has been reported to show potent antioxidant activity against reactive oxygen species. The aim of this study was ... -
Investigation of dermatology life quality index and serum prolactin and serum dehydroepiandrosterone sulphate levels in patients with chronic urticaria
Ucmak, Derya; Akkurt, Meltem; Ucmak, Feyzullah; Toprak, Gulten; Acar, Gurbet; Arica, Mustafa (Allergy Immunol Soc Thailand,, 2014)Background: Chronic urticaria (CU) is known to be one of the most disturbing diseases which significantly affect the quality of life. Prolactin (PRL) and DHEA-S (dehydroepiandrosterone sulfate) are stress-associated hormones ... -
An investigation of the effect of placental growth factor on intrapartum fetal compromise prediction in term-induced high risk pregnancies
Budak, Mehmet Sukru; Toprak, Gulten; Akgol, Sedat; Obut, Mehmet; Oglak, Cemil; Bagli, Ihsan; Kahramanoglu, Ilker (Via Medica, 2018)Objectives: To date, there is no available test to predict the risk of intrapartum fetal compromise (IFC) during labor, either starting spontaneously or induced due to obstetrics indications. The aim of this study was to ... -
Oxytocin Ameliorates Remote Liver Injury Induced by Renal Ischemia-Reperfusion in Rats
Hekimoglu, Askm Tas; Toprak, Gulten; Akkoc, Hasan; Evliyaoglu, Osman; Ozekinci, Selver; Kelle, Ilker (Korean Journal Of Physiology & Pharmacology, 2013)Renal ischemia-reperfusion (IR) causes remote liver damage. Oxytocin has anti-inflammatory and antioxidant effects. The main purpose of this study was to evaluate the protective function of oxytocin (OT) in remote liver ... -
A questionnaire study among nurses: awareness of blood and urine sample collection procedures
Yuksel, Hatice; Kaplan, Ibrahim; Toprak, Gulten; Evliyaoglu, Osman; Kus, Seyit; Azizoglu, Mustafa; Mete, Nuriye (Walter De Gruyter Gmbh, 2014)[Abstract Not Available]
