Browsing by Author "Stringfellow, Thomas C."

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NMR and amber analysis of the neamine pharmacophore for the design of novel aminoglycoside antibiotics

Andac, Cenk A.; Stringfellow, Thomas C.; Hornemann, Ulfert; Noyanalpan, Ningur (Academic Press Inc Elsevier Science, 2011)

The dependence of the solution structure of neamine on pH was determined by NMR and AMBER molecular dynamics methods at pD 3.3, pD 6.5, and pD 7.4 in D2O at 25 degrees C. Unlike neamine structures at pD 3.3 and 6.5, which ...