Browsing by Author "Kandemir, Sevgi İrtegün"
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Bazı Salvia (Ada Çayı) Türlerinin HPLC-IT-TOF-MS ile Taranması, Sekonder Metabolitlerinin Saflaştırılması ve Antikanser Özelliklerinin Belirlenmesi
Yılmaz, Mustafa Abdullah; Yener, İsmail; Ertaş, Abdulselam; Temel, Hamdi; Topçu, Gülaçtı; Kandemir, Sevgi İrtegün; Kolak, Ufuk (2018)Arazi çalışmaları sonucu toplanan 6 Salvia türünün ön biyolojik aktivite deneylerinde kullanılmak üzere kloroform ve etanol ekstreleri hazırlandı. Bu 12 ekstreden aktif çıkan etanol ekstrelerinden saf madde izolasyonuna ... -
Biological and chemical comparison of natural and cultivated samples of satureja macrantha C.A.Mey
Akdeniz, Mehmet; Yener, İsmail; Ertaş, Abdulselam; Fırat, Mehmet; Reşitoğlu, Barış; Haşimi, Nesrin; Kandemir, Sevgi İrtegün; Yılmaz, Mustafa Abdullah; Demirköz, Aslı Barla; Kolak, Ufuk; Öksuz, Sevil (ACG Publications, 2021)Abstract: In this study, investigation on the essential oils and ethanol extracts of naturally grown and cultivated Satureja macrantha samples were reported. The essential oil, flavour and terpenoid-steroid-flavonoid ... -
Biosynthesis, characterization, and investigation of antimicrobial and cytotoxic activities of silver nanoparticles using Solanum tuberosum peel aqueous extract
Xu, Jiajun; Yıldıztekin, Mahmut; Han, Dayong; Keskin, Cumali; Baran, Ayşe; Baran, Mehmet Fırat; Ava, Canan Aytuğ; Kandemir, Sevgi İrtegün (Elsevier Ltd., 2023)Metallic nanoparticle biosynthesis is thought to offer opportunities for a wide range of biological uses. The green process of turning biological waste into utilizable products gaining attention due to its economical and ... -
Diyabetik Sıçanların Testis Dokusunda VEGF ve Bcl-2 Ekspresyon Düzeylerinin İmmünohistokimya ve Western Blot Yöntemleri İle İncelenmesi
Deveci, Engin; Kandemir, Sevgi İrtegün (2016)Amaç: Bu çalışmada diyabetik sıçanların tetis dokusunda anjiogenezi ve vasküler geçirgenliği stimule eden vasküler endotel büyüme faktörünün (VEGF) ve apoptozis regülasyonunda önemli bir rol oynayan B-cell lymphoma-2' nin ... -
Ecofriendly synthesis of silver nanoparticles using ananas comosus fruit peels: Anticancer and antimicrobial activities
Baran, Ayşe; Keskin, Cumali; Baran, Mehmet Fırat; Huseynova, Irada; Khalilov, Rovshan; Eftekhari, Aziz; Kandemir, Sevgi İrtegün; Kavak, Deniz Evrim (Hindawi LTD, 2022)Metallic nanoparticles are valuable materials and have a range of uses. Nanoparticles synthesized from plant wastes by environment-friendly methods have attracted the attention of researchers in recent years. Also, the ... -
Ecofriendly/Rapid synthesis of silver nanoparticles using extract of waste parts of artichoke (Cynara scolymus L.) and evaluation of their cytotoxic and antibacterial activities
Baran, Ayşe; Baran, Mehmet Fırat; Keskin, Cumali; Kandemir, Sevgi İrtegün; Valiyeva, Mahbuba; Mehraliyeva, Sevil; Khalilov, Rovshan; Eftekhari, Aziz (Hindawi Limited, 2021)Recycling wastes and providing their use in useful fields attract attention every day. In our study, with the extract prepared from the parts of the Cynara scolymus L. (artichoke) plant that is not suitable for human ... -
Effects of electroporation on anticancer activity of 5-FU and newly synthesized zinc(II) complex in chemotherapy-resistance human brain tumor cells
Alkış, Mehmet Eşref; Turan, Nevin; Alan, Yusuf; Kandemir, Sevgi İrtegün; Buldurun, Kenan (Humana Press INC, 2021)Zn(II) complex of Schiff base derived from the condensation of 4-aminopyrimidine-2(1H)-one with salicylaldehyde was prepared and characterized by various physico-chemical and spectral methods for structure determination. ... -
Green synthesis, characterization of gold nanomaterials using gundelia tournefortii leaf extract, and determination of their nanomedicinal (Antibacterial, antifungal, and cytotoxic) potential
Keskin, Cumali; Baran, Ayşe; Baran, Mehmet Fırat; Hatipoğlu, Abdulkerim; Adican, Mehmet Tevfik; Atalar, Mehmet Nuri; Yavuz, Ömer; Kandemir, Sevgi İrtegün (Hindawi LTD, 2022)Introduction. Fighting against cancer and antibiotic resistance are important challenges of healthcare systems, and developing new treatment methods has become the most concentrated area of researchers. Method and Materials. ... -
Influence of extremely low-frequency magnetic field on chemotherapy and electrochemotherapy efficacy in human Caco-2 colon cancer cells
Alkış, Mehmet Eşref; Akdağ, Mehmet Zülküf; Kandemir, Sevgi İrtegün (Taylor & Francis, 2022)Although chemotherapy (CT) has some adverse effects on healthy tissues and cells, it is widely preferred for treating patients with cancer. Drug resistance is one of the major impediments to successful cancer treatment. ... -
Investigation of antimicrobial and cytotoxic properties and specification of silver nanoparticles (AgNPs) derived from cicer arietinum L. green leaf extract
Baran, Ayşe; Baran, Mehmet Fırat; Keskin, Cumali; Hatipoğlu, Abdulkerim; Yavuz, Ömer; Kandemir, Sevgi İrtegün (Frontiers Media SA, 2022)Using biological materials to synthesize metallic nanoparticles has become a frequently preferred method by researchers. This synthesis method is both fast and inexpensive. In this study, an aqueous extract obtained from ... -
Investigation of cytotoxic and apoptotic effects of 63 compounds obtained from Salvia species: Promising anticancer agents
Kandemir, Sevgi İrtegün; Fidan, Hilal Saruhan; Yener, İsmail; Mete, Nuriye; Ertaş, Abdulselam; Topçu, Gülaçtı; Kolak, Ufuk (Wiley, 2022)Since ancient time, Salvia L. species have been commonly used to treat colds, bronchitis, tuberculosis, heart diseases, and menstrual and digestive disorders in traditional medicine all around the world. They have been ... -
The nephroprotective effect of Quercetin in Cyclophosphamide-induced renal toxicity might be associated with MAPK/ERK and NF-κB signal modulation activity
Şeker, Uğur; Kavak, Deniz Evrim; Dokumacı, Fatma Zehra; Kızıldağ, Sefa; Kandemir, Sevgi İrtegün (Taylor and Francis Ltd., 2024)The present study aimed to examine the protective effect of quercetin (QUE) on cyclophosphamide (CTX)-induced nephrotoxicity. For that purpose, 24 mice were divided into four groups (Control, QUE, CTX, and CTX + QUE). The ... -
Phytochemical analysis and biological activity of Corchorus olitorius L.: Quantitative analysis of bioactive compounds by LC–MS/MS, antibacterial, enzyme inhibition, and cytotoxic activities
Atalar, Mehmet Nuri; Erenler, Ramazan; Turkan, Fikret; Alma, Mehmet Hakkı; Demirtaş, İbrahim; Baran, Ayşe; Kandemir, Sevgi İrtegün (Elsevier GmbH, 2023)Introduction: Corchorus olitorius L. is a significant plant in folk medicine, therefore, research on phytochemistry with biological activity may reveal its potential use in drug development. Medicinal plants are valuable ... -
Rapid biosynthesis of silver nanoparticles by Celtis tournefortii LAM. Leaf Extract; investigation of antimicrobial and anticancer activities
Baran, Ayşe; Keskin, Cumali; Kandemir, Sevgi İrtegün (Kahramanmaraş Sütçü İmam Üniversitesi, 2022)The usage of metallic nanoparticles are very common. Environmentally friendly approaches in obtaining nanoparticles attract a lot of attention because of their advantages. In this study, an easy and economical biosynthesis ... -
Serum level of ADAMTS4 and ADAMTS8 in patients with psoriatic arthritis
Taşkın, Irmak İçen; Kandemir, Sevgi İrtegün; Nas, Kemal; Dağlı, Abdullah Zübeyir (Erciyes University School of Medicine, 2021)Objective: Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis. A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) is a large family of proteoglycanase enzymes that ... -
Targeting soluble guanylate cyclase with Riociguat has potency to alleviate testicular ischaemia reperfusion injury via regulating various cellular pathways
Şeker, Uğur; Kavak, Deniz Evrim; Güzel, Barış Can; Baygeldi, Saime Betül; Yüksel, Meral; Kandemir, Sevgi İrtegün; Şener, Dila; Demirel, Özlem Unay (John Wiley and Sons Inc, 2022)Testicular ischaemia reperfusion (I/R) injury results with serious dysfunctions in testis. This study aims to explore effects of soluble guanylate cyclase (sGC) stimulator Riociguat on experimental testicular I/R injury ...
