Browsing by Author "Cim, Abdullah"
Now showing items 1-9 of 9
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Association between sequence variations of the Mediterranean fever gene and the risk of migraine: a case-control study
Coskun, Salih; Varol, Sefer; Ozdemir, Hasan H.; Celik, Sercan Bulut; Balduz, Metin; Camkurt, Mehmet Akif; Cim, Abdullah (Dove Medical Press Ltd, 2016)Migraine pathogenesis involves a complex interaction between hormones, neurotransmitters, and inflammatory pathways, which also influence the migraine phenotype. The Mediterranean fever gene (MEFV) encodes the pyrin protein. ... -
Association of polymorphisms in the vitamin D receptor gene and serum 25-hydroxyvitamin D levels in children with autism spectrum disorder
Coskun, Salih; Simsek, Seref; Camkurt, Mehmet Akif; Cim, Abdullah; Celik, Sercan Bulut (Elsevier Science Bv, 2016)Vitamin D is implicated in several aspects of human physiology, and polymorphisms in the vitamin D receptor gene (VDR) are associated with a variety of neuropsychiatric disorders. The aims of this study are to determine ... -
Association of Polymorphisms within the Serotonin Receptor Genes 5-HTR1A, 5-HTR1B, 5-HTR2A and 5-HTR2C and Migraine Susceptibility in a Turkish Population
Yucel, Yavuz; Coskun, Salih; Cengiz, Beyhan; Ozdemir, Hasan H.; Uzar, Ertugrul; Cim, Abdullah; Camkurt, M. Akif (Korean Coll Neuropsychopharmacology, 2016)Objective: Migraine, a highly prevelant headache disorder, is regarded as a polygenic multifactorial disease. Serotonin (5 HT) and their respective receptors have been implicated in the patogenesis. Methods: We investigated ... -
Contribution of polymorphisms in ESR1, ESR2, FSHR, CYP19A1, SHBG and NRIP1 genes to migraine susceptibility in Turkish population
Coskun, Salih; Yucel, Yavuz; Cim, Abdullah; Cengiz, Beyhan; Oztuzcu, Serdar; Varol, Sefer; Ozdemir, Hasan H. (Indian Acad Sciences, 2016)Migraine, a highly prevalent headache disorder, is regarded as a polygenic multifactorial disease, Single-nucleotide polymorphisms (SNPs) in the genes that involved in sex hormone metabolism may comprise risk for migraine, ... -
Factors influencing insulin usage among type 2 diabetes mellitus patients: A study in Turkish primary care
Yilmaz, Ahmet; Ak, Muharrem; Cim, Abdullah; Palanci, Yilmaz; Kilinc, Faruk (Taylor & Francis Ltd, 2016)Background: DM (diabetes mellitus) patients with poorly regulated blood glucose levels are at risk of increased morbidity and mortality. There are different factors that cause resistance to the initiation of insulin therapy ... -
Increased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats
Firat, Ugur; Kaya, Savas; Cim, Abdullah; Buyukbayram, Huseyin; Gokalp, Osman; Dal, Mehmet Sinan; Tamer, Mehmet Numan (Hindawi Publishing Corporation, 2012)Eryptosis is a term to define apoptosis of erythrocytes. Oxidative stress and hyperglycemia, both of which exist in the diabetic intravascular environment, can trigger eryptosis of erythrocytes. In this experimental study, ... -
Rhizomelic Chondrodysplasia Punctata Type 1 Caused by a Novel Mutation in the PEX7 Gene
Cim, Abdullah; Coskun, Salih; Gorukmez, Orhan; Yuksel, Hatice; Uluca, Unal; Di Pietro, Erminia; Plourde, Francois (Galenos Yayincilik, 2015)Peroxisomes are involved in various metabolic reactions. Rhizomelic chondrodysplasia punctata (RCDP) type 1 is one of the peroxisomal biogenesis disorders caused by mutations in the PEX7 gene and is inherited in an autosomal ... -
Serum IL-4 and IL-10 Levels Correlate with the Symptoms of the Drug-Naive Adolescents with First Episode, Early Onset Schizophrenia
Simsek, Seref; Yildirim, Veli; Cim, Abdullah; Kaya, Savas (Mary Ann Liebert, Inc, 2016)Objective: In this study, it was aimed to understand the underlying possible immunopathogenesis of first episode, early onset schizophrenia (EOS) through profiling the T helper 1 (Th-1) cell cytokines TNF-, IFN-, and IL-2, ... -
The spectrum of MEFV gene mutations and genotypes in Van province, the eastern region of Turkey, and report of a novel mutation (R361T)
Coskun, Salih; Ustyol, Lokman; Bayram, Yasemin; Bektas, M. Selcuk; Gulsen, Suleyman; Cim, Abdullah; Uluca, Unal (Elsevier, 2015)Familial Mediterranean fever (FMF) is the most common hereditary inflammatory periodic disease, characterized by recurrent episodes of fever and abdominal pain, synovitis, and pleuritis. The aim of this study was to determine ...
