Browsing by Author "Akil, Esref"
Now showing items 1-20 of 24
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ACUTE TOXIC EFFECTS OF METHYL ALCOHOL ON THE RAT BRAIN: THE PROTECTIVE EFFECTS OF CAFFEIC ACID PHENETHYL ESTER
Cevik, Mehmet Ugur; Varol, Sefer; Yucel, Yavuz; Akil, Esref; Uzar, E.; Kaplan, I; Can, Yazgan Umit (Carbone Editore, 2014)Background: Efficiency of caffeic acid phenethyl ester (CAPE) in reducing free radicals generated by oxidative stress has been previously reported. In the present study, the protective effect of CAPE on methyl alcohol ... -
Changes in serum albumin levels and neutrophil-lymphocyte ratio in patients with convulsive status epilepticus
Ozdemir, Hasan H.; Akil, Esref; Acar, Abdullah; Tamam, Yusuf; Varol, Sefer; Cevik, Mehmet Ugur; Arikanoglu, Adalet (Taylor & Francis Ltd, 2017)Aim: Inflammation may be involved in the ictogenesis and development of some partial epilepsies. Serum albumin levels and the neutrophil-lymphocyte ratio (NLR) are markers of inflammation. The aim of this study was to ... -
Clinical and Demographic Features of Pseudotumor Cerebri Syndrome Diagnosed in a University Hospital
Arslan, Demet; Arikanoglu, Adalet; Akil, Esref (Turkish Neurological Soc, 2017)Objective: Pseudotumor cerebri syndrome (PTCS) is characterized by symptoms and signs of increased intracranial pressure without ventriculomegaly, intracranial tumor or mass. This study aimed to explore and analyze 34 ... -
Double Filtration Plasmapheresis in the Treatment of a Case with Acute Disseminated Encephalomyelitis
Cevik, Mehmet Ugur; Cetincakmak, Mehmet Guli; Varol, Sefer; Akil, Esref (Turkish Neurological Soc, 2013)Acute disseminated encephalomyelitis (ADEM), is a monophasic autoimmune demyelinating disease of the central nervous system. Although high-dose steroid management has been considered the mainstay of treatment for ADEM, ... -
Echocardiographic Epicardial Fat Thickness and Neutrophil to Lymphocyte Ratio Are Novel Inflammatory Predictors of Cerebral Ischemic Stroke
Akil, Esref; Akil, Mehmet Ata; Varol, Sefer; Ozdemir, Hasan Huseyin; Yucel, Yavuz; Arslan, Demet; Akyuz, Abdurahman (Elsevier Science Bv, 2014)Background: The role of epicardial fat thickness (EFT) in ischemic stroke (IS) has not been previously investigated. The aim of the present study was to evaluate EFT and neutrophil/lymphocyte ratio (NLR) among patients ... -
Effects of Ecballium elaterium on brain in a rat model of sepsis-associated encephalopathy
Arslan, Demet; Ekinci, Aysun; Arici, Akgul; Bozdemir, Eda; Akil, Esref; Ozdemir, Hasan Huseyin (Taylor & Francis Ltd, 2017)Despite recent advances in antibiotic therapy, sepsis remains a major clinical challenge in intensive care units. Here we examined the anti-inflammatory and antioxidant effects of Ecballium elaterium (EE) on brain, and ... -
The effects of needle deformation during lumbar puncture
Ozdemir, Hasan Huseyin; Demir, Caner F.; Varol, Sefer; Arslan, Demet; Yildiz, Mustafa; Akil, Esref (Wolters Kluwer Medknow Publications, 2015)Objective: The aim of this study is to assess deformation of the tip and deflection from the axis of 22-gauge Quincke needles when they are used for diagnostic lumbar puncture (LP). Thus, it can be determined whether ... -
Evaluation of cerebral venous thrombosis secondary to oral contraceptive use in adolescents
Ozdemir, Hasan H.; Varol, Sefer; Akil, Esref; Acar, Abdullah; Demir, Caner F. (Springer-Verlag Italia Srl, 2015)Our goal was to evaluate the clinical patterns, additional risk factors, treatment and outcome of cerebral venous thrombosis (CVT) related to adolescent oral contraceptive pill (OCP) usage. We evaluated 22 patients with ... -
Facial diplegia: etiology, clinical manifestations, and diagnostic evaluation
Varol, Sefer; Ozdemir, Hasan Huseyin; Akil, Esref; Arslan, Demet; Aluclu, M. Ufuk; Demir, Caner F.; Yucel, Yavuz (Assoc Arquivos Neuro- Psiquiatria, 2015)Objective: Facial diplegia (FD) is a rare neurological manifestation with diverse causes. This article aims to systematically evaluate the etiology, diagnostic evaluation and treatment of FD. Method: The study was performed ... -
High-sensitivity C-reactive protein and high mobility group box-1 levels in Parkinson's disease
Baran, Aslihan; Bulut, Mahmut; Kaya, Mehmet Cemal; Demirpence, Ozlem; Sevim, Bunyamin; Akil, Esref; Varol, Sefer (Springer-Verlag Italia Srl, 2019)Various immunologic and inflammatory factors are contributed to pathogenesis of Parkinson's disease (PD). High mobility group box-1 (HMGB1) is a protein that plays certain roles in inflammation, DNA repair, transcription, ... -
Identifying autonomic nervous system dysfunction in acute cerebrovascular attack by assessments of heart rate variability and catecholamine levels
Akil, Esref; Tamam, Yusuf; Akil, Mehmet Ata; Kaplan, Ibrahim; Bilik, Mehmet Zihni; Acar, Abdullah; Tamam, Banu (Georg Thieme Verlag Kg, 2015)Objective: This study aimed to evaluate changes in the autonomic nervous system caused by cerebral lesions due to acute stroke. We assessed heart rate variability and catecholamine levels in lieu of stroke lesion localization. ... -
The increase of carcinoembryonic antigen (CEA), high-sensitivity C-reactive protein, and neutrophil/lymphocyte ratio in Parkinson's disease
Akil, Esref; Bulut, Aslihan; Kaplan, Ibrahim; Ozdemir, Hasan Huseyin; Arslan, Demet; Aluclu, Mehmet Ufuk (Springer-Verlag Italia Srl, 2015)The role of carcinoembryonic antigen (CEA) in Parkinson's disease (PD) has not been previously investigated. The aim of the present study was to evaluate the serum level of carcinoembryonic antigen, high-sensitivity ... -
The Increase of The Mean Platelet Volume in Patients With Intracerebral Haemorrhage
Arikanoglu, Adalet; Cevik, Mehmet Ugur; Uzar, Ertugrul; Acar, Abdullah; Akil, Esref; Ekici, Faysal; Tasdemir, Nebahat (Galenos Publ House, 2012)Objective: The mean platelet volume (MPV) is a biomarker of platelet function and activity. The influence of platelet function disorders on the aetiology of intracerebral haemorrhages (ICH) and mortality is not clear yet. ... -
Increased fibrinogen, D-dimer and galectin-3 levels in patients with migraine
Yucel, Yavuz; Tanriverdi, Halis; Arikanoglu, Adalet; Varol, Sefer; Kaplan, Ibrahim; Akil, Esref; Celepkolu, Tahsin (Springer-Verlag Italia Srl, 2014)There are limited studies evaluating the fibrinogen levels in patients with migraine. It remains unknown whether the levels of the haematological marker of thromboembolism, d-dimer, and the levels of galectin-3, which plays ... -
Investigation of Mean Platelet Volume and Platelet Count in the Blood of Patients with Migraine
Varol, Sefer; Akil, Esref; Cevik, Mehmet Ugur; Celepkolu, Tahsin; Yucel, Yavuz; Tanriverdi, Mehmet Halis; Aluclu, Mehmet Ufuk (Turkish Neurological Soc, 2013)Objective: Mean platelet volume (MPV) is an indicator for platelet function and activation. Studies researching MPV and platelet level on the patients with migraine are insufficient. In this study, we aimed to find a ... -
Investigation of Total Oxidants/Antioxidants in Patients with Intracerebral Haemorrhage
Cevik, Mehmet Ugur; Acar, Abdullah; Yucel, Yavuz; Varol, Sefer; Akil, Esref; Arikanoglu, Adalet; Yuksel, Hatice (Turkish Neurological Soc, 2013)Objective: Although there are numerous studies about oxidants and antioxidants in patients with ischemic stroke, the number of studies on this subject in patients with intracerebral hemorrhage (ICH) is limited. Malondialdehyde ... -
Just Get Headache... Isolated Transverse Sinus Venous Thrombosis
Ozhasenekler, Ayhan; Durgun, Hasan Mansur; Kacmaz, Omer; Tunc, Ibrahim; Akil, Esref; oner, Hakan (Aves, 2013)Cerebral venous thrombosis is a rare condition than arterial oclusive disease of brain. While sagittal and cavernous sinus thrombosis are frequently seen, transverse sinus thrombosis is rare. Clinically, headache is the ... -
Low fetuin-A level in migraine: a case-control study
Tanriverdi, Mehmet Halis; Varol, Sefer; Arikanoglu, Adalet; Bucaktepe, Pakize Gamze Erten; Celepkolu, Tahsin; Akil, Esref; Yuksel, Hatice (Springer-Verlag Italia Srl, 2014)Migraine is a type of primary headache which is caused by the alterations in trigeminovascular system. Migraine attacks are associated with neurovascular inflammation of the cerebral and extracerebral vessels, but its ... -
Oxidative Damage is Ameliorated by Curcumin Treatment in Brain and Sciatic Nerve of Diabetic Rats
Acar, Abdullah; Akil, Esref; Alp, Harun; Evliyaoglu, Osman; Kibrisli, Erkan; Inal, Ali; Unan, Fatma (Taylor & Francis Ltd, 2012)To date, there have not been enough studies about the effects of curcumin against oxidative stress on sciatic nerves caused by streptozotocin (STZ) in diabetic rats. Therefore, this study was undertaken to determine whether ... -
THE PLASMA LEVEL OF PARATHORMON AND HOMOCYSTEINE IN MIGRAINE PATIENTS; ANOTHER ASPECT ON MIGRAINE-STROKE ASSOCIATON
Varol, Sefer; Akil, Esref; Yunce, Muharrem; Kaplan, Brahim; Ozdemir, Hasan Huseyin; Arslan, Demet; Yilmaz, Ahmet (Carbone Editore, 2015)The pathogenesis of migraine has been well studied and it is associated with oxidative stress, neurogenic inflammation, and endothelial dysfunction. To the best of our knowledge, no studies have focused on the impact of ...