Browsing by Author "Akdeniz, Mehmet"
Now showing items 1-20 of 31
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Bioguided isolation of secondary metabolites from Salvia cerino-pruinosa Rech. f. var. cerino-pruinosa
Ertaş, Abdulselam; Çakırca, Hatice; Yener, İsmail; Akdeniz, Mehmet; Fırat, Mehmet; Topçu, Gülaçtı; Kolak, Ufuk (ACG Publications, 2021)Abstract: In the current study, the ethanol extracts prepared from the aerial parts and roots of an endemic species, Salvia cerino-pruinosa Rech. f. var. cerino-pruinosa were fractionated on silica gel columns and tested for ... -
Bioguided Isolation of Secondary Metabolites fromSalvia cerino-pruinosa Rech. f. var. cerino-pruinosa
Kolak, Ufuk; Ertas, Abdulselam; Firat, Mehmet; Cakirca, Hatice; Topcu, Gulacti; Yener, Ismail; Akdeniz, Mehmet (2021)In the current study, the ethanol extracts prepared from the aerial parts and roots of an endemicspecies, Salvia cerino-pruinosa Rech. f. var. cerino-pruinosa were fractionated on silica gel columns and testedfor determination ... -
Biological and chemical comparison of natural and cultivated samples of satureja macrantha C.A.Mey
Akdeniz, Mehmet; Yener, İsmail; Ertaş, Abdulselam; Fırat, Mehmet; Reşitoğlu, Barış; Haşimi, Nesrin; Kandemir, Sevgi İrtegün; Yılmaz, Mustafa Abdullah; Demirköz, Aslı Barla; Kolak, Ufuk; Öksuz, Sevil (ACG Publications, 2021)Abstract: In this study, investigation on the essential oils and ethanol extracts of naturally grown and cultivated Satureja macrantha samples were reported. The essential oil, flavour and terpenoid-steroid-flavonoid ... -
Biological and Chemical Comparison of Natural and CultivatedSamples of Satureja macrantha C.A.Mey.
Akdeniz, Mehmet; Hasimi, Nesrin; Ertas, Abdulselam; Oksuz, Sevil; Demirkoz, Asli Barla; Resitoglu, Baris; Yener, Ismail (2021)In this study, investigation on the essential oils and ethanol extracts of naturally grown and cultivatedSatureja macrantha samples were reported. The essential oil, flavour and terpenoid-steroid-flavonoid contents of ... -
Chemical compositions by LC-MS/MS and GC-MS and biological activities of Chenopodium album subsp. album var. microphyllum
Yilmaz, Pelin Koseoglu; Ertas, Abdulselam; Akdeniz, Mehmet; Avci, Mine Kocyigit; Kolak, Ufuk (Elsevier, 2019)Chenopodium species have been used in folk medicine and as vegetable for years. In the present study, the total phenolic and flavonoid contents, biological activities, phenolic constituents and fatty acid profile of ... -
Comparison of chemical and biological properties of in vivo and in vitro samples of Salvia siirtica Kahraman, Celep & Dogan extracts prepared with different solvents
Fidan, Hilal Saruhan; Kilinc, Fatih Mehmet; Yilmaz, Mustafa Abdullah; Akdeniz, Mehmet; Yener, Ismail; Firat, Mehmet; Onay, Ahmet (Elsevier, 2021)The use of Salvia species among the public and their importance in the scientific world increase due to their numerous pharmacological and biological activities on a daily basis. In this study, the phytochemical contents ... -
A comprehensive LC-MS/MS method validation for the quantitative investigation of 37 fingerprint phytochemicals in Achillea species: A detailed examination of A. coarctata and A. monocephala
Yilmaz, Mustafa Abdullah; Ertas, Abdulselam; Yener, Ismail; Akdeniz, Mehmet; Cakir, Oguz; Altun, Muhammed; Demirtas, Ibrahim (Elsevier Science Bv, 2018)The current study aims to optimize and validate a comprehensive LC-MS/MS method for the quantification of 37 phytochemicals (15 phenolic acids, 17 flavonoids, 3 non-phenolic organic acids, 1 phenolic aldehyde and 1 ... -
Comprehensive study of chemical composition and biological activity of Thymus pubescens Boiss. et Kotschy ex Celak
Yigitkan, Serkan; Akdeniz, Mehmet; Yener, Ismail; Seker, Zeki; Yilmaz, Mustafa Abdullah; Firat, Mehmet; Kavak, Deniz Evrim (Elsevier, 2022)The use of Thymus species amongst the public and their importance in the scientific world is increasing day by day. In addition to being consumed as tea and spice, Thymus species are used as folk medicine for respiratory, ... -
A comprehensive study on chemical and biological investigation of thymus brachychilus jalas: A rich source of ursolic and oleanolic acids
Akdeniz, Mehmet; Yiğitkan, Serkan; Yılmaz, Mustafa Abdullah; Yener, İsmail; Varhan Oral, Elif; Fırat, Mehmet; Orhan, İlkay Erdoğan (Taylor & Francis Inc, 2023)The significance of Thymus species in the scientific community is growing steadily due to their extensive utilization in traditional medicine, food industry, and pharmaceutical sector, owing to their abundance in essential ... -
Content analysis, nanoparticle forming potential and acaricidal effects on Tick (Hyalomma marginatum) of essential oils from two common Thymbra species
Kaya, Eda Cavus; Akdeniz, Mehmet; Ugurlu, Pelin; Yener, Ismail; Firat, Mehmet; Ertas, Abdulselam (Taylor & Francis Ltd, 2024)In this study, the fatty acid, essential oil and aroma composition of Thymbra sintenisii Bornm. & Aznav. subsp. sintenisii Bornm. & Aznav (TSS) and Thymbra sintenisii Bornm. & Azn. subsp. isaurica P.H.Davis (TSI) were ... -
Cream production and biological in vivo/in vitro activity assessment of a novel boron-based compound derived from quercetin and phenyl boronic acid
Temel, Hamdi; Atlan, Metin; Ertaş, Abdulselam; Yener, İsmail; Akdeniz, Mehmet; Yazan, Zehra; Yılmaz, Mustafa Abdullah (Elsevier GmbH, 2022)Boronic acids constitute an important class of synthetic intermediates due to their high chemical stability, ease of use, moderate organic Lewis acid properties, reduced reactivity profiles and numerous biological activities ... -
A detailed biological and chemical investigation of sixteen schillea species' essential oils via chemometric approach
Yener, İsmail; Yılmaz, Mustafa Abdullah; Ölmez, Özge Tokul; Akdeniz, Mehmet; Tekin, Fetullah; Haşimi, Nesrin; Alkan, Mehmet Hüseyin; Öztürk, Mehmet; Ertaş, Abdülselam (Wiley-V C H Verlag Gmbh, 2020)Representatives of the Achillea genus are widely used as foods or nutraceuticals. Considering the increasing demand for herbal dietary supplements with health promoting effects, the objective of this research was to evaluate ... -
Determination of enzyme inhibition potential and anticancer effects of pistacia khinjuk stocks raised in in vitro and in vivo conditions
Tilkat, Emine Ayaz; Batıbay, Hayri; Yener, İsmail; Yılmaz, Pelin Köseoğlu; Akdeniz, Mehmet; Kaplan, Alevcan; Ercişli, Sezai; Ertas, Abdulselam; Holubec, Vojtech (MDPI, 2021)In this study, antihypertensive, anticholinesterase, antiurease, antityrosinase and antielastase enzyme inhibition and anticancer activities of in vivo (male and female) and in vitro samples (root, stem and leaf parts) of ... -
Determination of essential oil and biological activities of Hypericum ternatum Poulter and H. scabrum L. species collected from different localities: is H. scabrum an alternative to multifunctional species ST JOHN'S WORT (H. perforatum)?
Akdeniz, Mehmet; Yener, Ismail; Irtegun Kandemir, Sevgi; Ozhan Kocakaya, Safak; Firat, Mehmet; Yigitkan, Serkan; Hasimi, Nesrin (Tubitak Scientific & Technological Research Council Turkey, 2022)The importance of Hypericum L. species, being used in traditional medicine, in the scientific world is increasing day by day. Hypericum species are plants that have been used in the treatment of many diseases for a long ... -
Determination of fingerprints contents of different extracts and parts of six endemic Salvia taxa by GC-MS: Source species for valuable compounds with drug or drug potential
Akdeniz, Mehmet; Yener, İsmail; Dinçel, Demet; Fırat, Mehmet; Değirmenci, Dilek Karataş; Ertaş, Abdulselam (Wiley, 2022)Public use of Salvia species and their importance in the scientific world is continually increasing. It is known that this use and the importance of Salvia species are mostly due to the terpenoid compounds that they contain. ... -
Essential oil content, in-vitro and in-silico activities of Hypericum triquetrifolium Turra, H. empetrifolium subsp. empetrifolium Willd., and H. pruinatum Boiss. & Balansa species
Akdeniz, Mehmet; Yener, Ismail; Kocakaya, Safak Ozhan; Yolcu, Murat; Yigitkan, Serkan; Aydin, Firat; Turkmenoglu, Fatma Pinar (Istanbul Univ, Fac Pharmacy, 2023)Background and Aims: The importance of Hypericum species that are used traditionally against many diseases is increasing day by day.Methods: In this study, the essential oil contents of Hypericum triquetrifolium, H. ... -
Essential oil contents of Hypericum linarioides , H. helianthemoides, and H. lydium with their biological activities: Importance of Hypericum genus in the cosmeceutical and pharmaceutical industries
Akdeniz, Mehmet; Yener, İsmail; Ertaş, Abdülselam; Dincel, Demet; Fırat, Mehmet; Kocakaya, Şafak Özhan; Yigitkan, Serkan; Türkmenoğlu, Fatma Pınar; Aydın, Fırat; Kolak, Ufuk (Springer, 2023)In the literature, more than 3000 studies have been carried out on species in the Hypericum genus in the last ten years, especially for H. perforatum. The importance of Hypericum species in traditional medicine and modern ... -
Essential oil, aroma, and fatty acid profiles of five endemic Salvia taxa from Turkey with chemometric analysis
Ertaş, Abdulselam; Akdeniz, Mehmet; Yener, İsmail; Öztürk, Mehmet; Ölmez, Özge Tokul; Fırat, Mehmet; Kolak, Ufuk (Wiley-V C H Verlag GMBH, 2022)The essential oil, aroma, and fatty acid compositions of Salvia cerino-pruinosa var. cerino-pruinosa, S. cerino-pruinosa var. elazigensis, S. pseudeuphratica, S. rosifolia, and S. kurdica collected in 2015, 2016, and 2017 ... -
A GC-MS method validation for quantitative investigation of some chemical markers inSalvia hypargeiaFisch. & CA Mey. of Turkey: Enzyme inhibitory potential of ferruginol
Bakir, Derya; Akdeniz, Mehmet; Ertas, Abdulselam; Yilmaz, Mustafa A.; Yener, Ismail; Firat, Mehmet; Kolak, Ufuk (Wiley, 2020)In the present study, a GC-MS method used for quantitative screening of 26 compounds (sclareolide, sclareol, ferruginol, cryptanol, 6,7-dehydroroyleanone, suginal, 9,10-dihydro-7,8-dimethyl-2-(1-methylethyl) phenanthren-3-ol, ... -
Isolation of secondary metabolites of two endemic species: Salvia rosifolia Sm. and Salvia cerino-pruinosa Rech. f. var. elazigensis (Lamiaceae)
Yarış, Esra; Adsız, Leyla Balur; Yener, İsmail; Tuncay, Eyyüp; Yılmaz, Mustafa Abdullah; Akdeniz, Mehmet; Kaplaner, Erhan; Fırat, Mehmet; Ertaş, Abdulselam; Kolak, Ufuk (Springer, 2021)In the present study, activity-guided isolation and structural elucidation of antioxidant secondary metabolites of ethanol extracts prepared from the root and aerial parts of Salvia rosifolia and Salvia cerino-pruinosa ...
