Browsing by Author "Aşır, Fırat"

ADM and SFLT-1 Eexpression in placentas with gestational diabetes mellitus

Arslan, Necat; Söker, Sevda İpek; Başaran, Süreyya Özdemir; Kaplan, Özge; Aşır, Fırat; Deveci, Engin; Şeker, Uğur (Merthan Tunay, 2023)

Aim: In this study, we aimed to examine the expression levels of Adrenomedullin (ADM) and soluble fms-like tyrosine kinase-1 (sFlt-1), two novel proteins found to be involved in vascular regulation in gestational diabetes ...

The changes in Hoffbauer and syncytiotrophoblast cells in serious preeclampsia complicated with hellp syndrome (Ultrastructural and immunohistochemical study)

Nergiz, Yusuf; Nergiz, Şebnem; Aşır, Fırat; Deveci, Engin; Sak, Erdal; Evsen, Sıddık; Tunik, Selçuk; Şeker, Uğur (INESEG Yayıncılık, 2022)

HELLP syndrome is a syndrome characterized by hemolytic anemia, increased liver enzymes, and thrombopenia and can be seen in 1% of all pregnancies, 10-20% of pregnancies with pain, preeclampsia, and eclampsia. HELLP syndrome ...

Effect of aloe vera on Mmp-1 and Timp-1 expression on diabetic wound healing

Seyrek, Rohlat; Söker, Sevda; Kaplan, Özge; Başaran, Süreyya Özdemir; Aşır, Fırat; Deveci, Engin; Şeker, Uğur (Merthan Tunay, 2023)

Aim: The aim of this study is to investigate the healing aspect of aloe vera in diabetes mellitus, which inhibits wound healing. Methods: Diabetes model was created with streptozotocin. At the end of the 14-day experiment, ...

Effect of ellagic acid on damage caused by hepatic ischemia reperfusion in rats

Durgun, Cemalettin; Aşır, Fırat (Verduci Editore s.r.l, 2022)

OBJECTIVE: Ischemia (I) causes lack of oxygen delivery to the tissues, leading to hypoxia and cellular damage. Reperfusion (R) is the re-blooded of the tissue; however, it may cause more tissue damage than ischemia alone ...

The effects of ellagic acid on experimental corrosive esophageal burn injury

Keşim, Dilek Aygün; Aşır, Fırat; Ayaz, Hayat; Korak, Tuğcan (Multidisciplinary Digital Publishing Institute (MDPI), 2024)

This study aimed to investigate the antioxidant effect of Ellagic acid (EA) on wound healing in sodium hydroxide (NaOH)-induced corrosive esophageal burn injury. The interaction networks and functional annotations were ...

Effects of quince gel and hesperidin mixture on experimental endometriosis

Ermiş, Işılay Sezen; Deveci, Engin; Aşır, Fırat (Multidisciplinary Digital Publishing Institute (MDPI), 2023)

Objectives: Endometriosis (EM) is the presence of endometrial tissue outside the uterus. This study aimed to examine the effects of quince gel and hesperidin treatment on uterine tissue in an experimental endometriosis ...

Efficacy of taxifolin in the prevention of renal injury due to liver ischemia and reperfusion

Ülger, Burak Veli; Durgun, Hasan Mansur; Aşır, Fırat; Varlı, Metin; Gündüz, Ercan (2023)

Aim: During surgical procedures such as liver resection and transplantation, ischemia/reperfusion (I/R) injury and related complications may occur at a rate of approximately 10%. Our study, we planned to investigate ...

EXAMINATION OF APOPTOTIC CHANGES IN AROMATIC HYDROCARBON BENZENEADMINISTERED RAT TESTICULAR TISSUE WITH HISTOPATHOLOGICAL METHODS

Aşır, Fırat; Özkorkmaz, Ebru Gökalp; Yıldızhan, Eda; Akkuş, Murat; Kaya, Nalan; Koyutürk, Leyla Canpolat (2021)

Benzene is an aromatic hydrocarbon and a colorless and odorous liquid. It is used in the production of plastics, detergents, pesticides, and other chemicals. Serious deterioration is seen in sperm production of men who are ...

Ganoderma lucidum alleviates ischemia- reperfusion-induced renal injury in wistar rats

Dönder, Ahmet; Aşır, Fırat (SCI Printers & Publication INC, 2021)

OBJECTIVE: To investigate effects of Ganoderma lucidum (G. lucidum) kidney sections of rats induced by ischemia-reperfusion (I/R) injury. STUDY DESIGN: A total of 40 rats were assigned to 4 groups: control (Sham), I/R, ...

Hesperidin may protect gastric tissue against immobilization stress

Beskisiz, Songül; Aşır, Fırat (SCI Printers & Publication INC, 2021)

OBJECTIVE: To investigate antioxidant properties of hesperidin against gastric lesions in immobilized rats with immunostaining of caspase-3 and IL-10. STUDY DESIGN: Thirty male Wistar albino rats were assigned to control, ...

Immune activity of Ki-67 during nasal polyp development

Haznedar, Berzan; Kaplan, Özge; Aşır, Fırat; Ermiş, Işılay Sezen (Verduci Editore s.r.l, 2023)

OBJECTIVE: Nasal polyps are non-cancerous, soft painless growth of nasal mucosa. In this study, our aim was to investigate the Ki-67 expression level in nasal polyps by immunohistochemical method. PATIENTS AND METHODS: 30 ...

Immunohistochemical analysis of vimentin and Zonula Occludens-1 in placentas of patients with PPROM

Zaman, Fuat; Aşır, Fırat; Ermiş, Işılay Sezen; Tuncer, Mehmet Cudi; Deveci, Engin; Oğlak, Süleyman Cemil (IMR Press Limited, 2024)

Background: We aimed to investigate the immunohistochemical staining of vimentin and zonula occludens-1 (ZO-1) expression in the placentas of pregnant women with preterm premature rupture of membranes (PPROM). Methods: ...

Investigation of Beclin 1 and TNF-? expressions in preeclampsia placentas: Immunohistochemical study

Öcal, Ece; Toprak, Veysel; Akalın, Senem Alkan; Aşır, Fırat; Deveci, Engin (Lippincott Williams and Wilkins, 2023)

Background: Preeclampsia is a pregnancy complication Aim of this study was to investigate expression of Beclin1 and tumor necrosis factor (TNF)-α in normotensive and preeclamptic placentas of pregnant women patients. ...

INVESTIGATION OF GLOBOZOOSPERMIA’S MORPHOLOGICAL STRUCTURE AND DNA FRAGMENTATION IN OLIGOZOOSPERMIA CASES IN INFERTILE MALES

Yıldızhan, Eda; Çankırı, Zuhal; Akıncı, Dilara; Aşır, Fırat; Afşin, Muhamet; Akkuş, Murat; Dede, Onur (2022)

Total globozoospermia is diagnosed by the presence of 100% round-headed spermatozoa without acrosomes. It is still unclear whether patients whose ejaculate contains both normal and globozoospermic cells (partial globozoospermia) ...

Investigation of placental hofbauer cells byimmunohistochemistry methods in complicated pregnancies

Nergiz, Yusuf; Nergiz, Şebnem; Aşır, Fırat; Şahin, Ayşe; Ağaçayak, Elif (International Engineering, Science and Education Group, 2021)

Development of the placenta without any complication is essential for normal pregnancy.The placenta is a multifunctional organ that plays a vital role in fetal development. Hofbauer cells areone of the most important groups ...

Investigation of the effects of carvacrol on experimental ischemia/reperfusion model of rat ovaries by immunohistochemistry

Peker, Nurullah; Değer, Uğur; Aşır, Fırat (SCI Printers & Publication INC, 2020)

Abstract OBJECTIVE: Ovarian torsion is a gynecologic problem that presents as acute lower abdominal pain. As a result, blood flow to the ovaries decreases and ischemia develops. Many medications have been used to treat ...