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Öğe Effect of different doses pmsg on estrus synchronization andfertility in awassi ewes synchronized with progesterone duringthe transition period(2011) Zonturlu A.K.; Özyurtlu N.; Kaçar C.The aim of the present study was to evaluate different of doses PMSG on estrus synchronization and fertility in Awassi ewessynchronized with progesterone during The transition period. A total of 92 ewes were used in this experiment. All ewes were treated witha vaginal sponge containing 30 mg fluorogestone acetate (FGA) inserted into the vagina of the ewes for 12 days. All animals were dividedinto four groups randomly and a single intramuscular (IM) dose of PMSG (group 1, 300 IU, n=21; group 2, 400 IU, n=27; group 3, 500 IU,n= 25), group 4 (n=19) was injected with 1 ml normal saline solution and as served control group at time of sponge removal. The intervalbetween the withdrawal of the sponges and estrus was observed 40.82±1.21 h, 40.20±1.14 h, 38.7±1.07 h and 41.79±1.72 h in groups 1, 2, 3 and the control group, respectively. Estrus responses were similar in all groups (group 1, 81.0%; group 2, 92.6%; group 3, 92.0%;control group, 73.78%). There were no statistically significant differences (P>0.05) between the treatment groups and the control groupfor the onset of estrus or estrus response. The duration of estrus was shorter in group 1, compared to the control group (24.9±0.85 hrvs. 29.07±1.31hr), and that this difference was statistically significant (P<0.05). Pregnancy rates were 82.35%, 80.0%, 82.60% and 78.5% ingroups 1, 2, 3 and the control group, respectively. Lambing rates were obtained 100.0% among all the groups, or litter size (1.07 to 1.21)did not differ between the treatment groups and the control group. As a result, different doses of PMSG in Awassi ewes synchronized withprogesterone during the transition period had similar effect on estrus synchronization and fertility parameters.Öğe Immunohistochemical localisation of oestrogen and epidermal growth factor receptors of the bitch uterus in the sexual cycle(2010) Ozyurtlu N.; Sagsoz H.; Saruhan B.G.; Zonturlu A.K.; Ketani M.A.; Akbalik M.E.The localisation of oestrogen (ER) and epidermal growth factor receptors (EGFR) in the various cell types of the bitch uterine was determined. In this study, 23 adult, healthy crossbred bitches brought to the clinic for ovariohisterectomy were used. ER and EGFR positive staining was detected in all cell types of the uterus. A distinct staining was seen in the luminal and glandular epithelium; while stromal and myometrial cells showed weak or moderate staining. The endothelial and smooth muscle cells of the vessels in the endometrium and myometrium sometimes appeared positive. No staining was observed in the mesothelium. The results of this study suggested that ER and EGFR were expressed at various levels in different cell types of bitch uterus. In light of the previous studies, and data of the presented investigations, it may be necesssary to elicit the harmonious proliferation and differentiation of epithelial and stromal cells that are considered essential for the preparation of the uterus for implantation.Öğe Synchronization of estrus using FGA and CIDR intravaginal pessaries during the transition period in Awassi ewes(2008) Zonturlu A.K.; Aral F.; Ozyurtlu N.; Yavuzer U.The objective of this study was to investigate the efficiency of synchronization using different progesterone treatments during transition period from the non-breeding to the natural breeding season. Thirty-four non-lactating Awassi ewes were randomly assigned to two groups, treated with fluorogestone acetate (FGA group, n = 19) or controlled internal drug release devices (CIDR group, n = 15) for 12 days. After pessary and sponges removal, all ewes received an intramuscular injection of 300 IU. eCG. There was no significant differences between treatments for ewes in estrus (FGA: 84.2%, CIDR: 86.6%). The onset of estrus from progestagen treatments, FGA and CIDR groups was (mean±SD.) 45.00±1.00 and 36.00±3.40, respectively. Interval from the cessation of treatment to the onset of estrus was significantly (p<0.05) longer in FGA, compared to the CIDR. The duration of the induced estrus period did not differ significantly between in 2 treatment groups. Pregnacy rate did not differ (p>0.05) between FGA (52.63%) and CIDR (60.00%). As a result, Estrus synchronization with FGA and CIDR is found to be similar, although the onset time of estrus varies with the use of FGA or CIDR. © Medwell Journals, 2008.